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Murcko scaffold

Ring system with 2 rings and 13 atoms

70 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
70
With full pages
9
Scaffold SMILES

O=c1ccn(C2CCCO2)c(=S)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ccn(C2CCCO2)c(=S)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 70 chemicals

2-Thiothymidine chemical structure, C10H14N2O4S, CAS 28585-51-5
2-Thiothymidine
CAS 28585-51-5C10H14N2O4S
5-Ethyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one chemical structure, C11H16N2O4S, CAS 27089-52-7
5-Ethyl-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one
CAS 27089-52-7C11H16N2O4S
2'-Deoxy-5-propyl-2-thiouridine chemical structure, C12H18N2O4S, CAS 344410-45-3
2'-Deoxy-5-propyl-2-thiouridine
CAS 344410-45-3C12H18N2O4S
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-5-vinyl-pyrimidin-4-one chemical structure, C11H14N2O4S, CAS 613216-46-9
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-5-vinyl-pyrimidin-4-one
CAS 613216-46-9C11H14N2O4S
[[(2R,3S,5R)-3-Fluoro-5-(5-methyl-4-oxo-2-thioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate chemical structure, C10H16FN2O12P3S, CAS 667426-99-5
[[(2R,3S,5R)-3-Fluoro-5-(5-methyl-4-oxo-2-thioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate
CAS 667426-99-5C10H16FN2O12P3S
1-[(2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one chemical structure, C10H14N2O5S, CAS 875302-27-5
1-[(2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-2-sulfanylidenepyrimidin-4-one
CAS 875302-27-5C10H14N2O5S
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one chemical structure, C9H12N2O4S, CAS 35059-12-2
1-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one
CAS 35059-12-2C9H12N2O4S
5-Fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one chemical structure, C9H11FN2O4S, CAS 152310-66-2
5-Fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one
CAS 152310-66-2C9H11FN2O4S
5-Chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one chemical structure, C9H11ClN2O4S, CAS 169557-05-5
5-Chloro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-thioxo-pyrimidin-4-one
CAS 169557-05-5C9H11ClN2O4S
5-Fluoro-2-thio-2'-deoxyuridylate chemical structure, C9H12FN2O7PS, CAS 151134-50-8
5-Fluoro-2-thio-2'-deoxyuridylate
CAS 151134-50-8C9H12FN2O7PS
2-Thiouridine chemical structure, C9H12N2O5S, CAS 20235-78-3
2-Thiouridine
CAS 20235-78-3C9H12N2O5S
5-Methylaminomethyl-2-thiouridine chemical structure, C11H17N3O5S, CAS 32860-54-1
5-Methylaminomethyl-2-thiouridine
CAS 32860-54-1C11H17N3O5S
2-Thio-5-carboxymethyluridine chemical structure, C11H14N2O7S, CAS 58479-77-9
2-Thio-5-carboxymethyluridine
CAS 58479-77-9C11H14N2O7S
5-Carboxymethylaminomethyl-2-thiouridine chemical structure, C12H17N3O7S, CAS 78173-95-2
5-Carboxymethylaminomethyl-2-thiouridine
CAS 78173-95-2C12H17N3O7S
1-(beta-D-Ribofuranosyl)-2-thio-uracil-5'-phosphate chemical structure, C9H13N2O8PS, CAS 41686-01-5
1-(beta-D-Ribofuranosyl)-2-thio-uracil-5'-phosphate
CAS 41686-01-5C9H13N2O8PS
5-Methyl-2-thiouridine chemical structure, C10H14N2O5S, CAS 32738-09-3
5-Methyl-2-thiouridine
CAS 32738-09-3C10H14N2O5S
1-[(2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one chemical structure, C9H12N2O4S, CAS 455951-69-6
1-[(2R,3R,5S)-3-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-sulfanylidenepyrimidin-4-one
CAS 455951-69-6C9H12N2O4S
2-Thiothymidine triphosphate chemical structure, C10H17N2O13P3S, CAS 322728-17-6
2-Thiothymidine triphosphate
CAS 322728-17-6C10H17N2O13P3S
2'-O-Methyl-2-thiouridine chemical structure, C10H14N2O5S, CAS 113886-72-9
2'-O-Methyl-2-thiouridine
CAS 113886-72-9C10H14N2O5S
2',3'-Dideoxy-2-thiouridine chemical structure, C9H12N2O3S, CAS 162894-46-4
2',3'-Dideoxy-2-thiouridine
CAS 162894-46-4C9H12N2O3S
5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine chemical structure, C13H16F3N3O6S, CAS 89128-99-4
5-(N-Methyl-N-trifluoroacetyl-aminomethyl)-2-thiouridine
CAS 89128-99-4C13H16F3N3O6S
Ctk2A3325 chemical structure, C12H18N2O6S, CAS 647839-20-1
Ctk2A3325
CAS 647839-20-1C12H18N2O6S
Ctk2A3326 chemical structure, C11H16N2O6S, CAS 647839-15-4
Ctk2A3326
CAS 647839-15-4C11H16N2O6S
Ctk2A3328 chemical structure, C12H16N2O5S, CAS 647839-07-4
Ctk2A3328
CAS 647839-07-4C12H16N2O5S