CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 26 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
21
With full pages
3
Scaffold SMILES

O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

Ethyl 4-[N-(4-chlorobenzyl)-N-(phenylsulfonyl)glycyl]piperazine-1-carboxylate chemical structure, C22H26ClN3O5S, CAS 433244-76-9
Ethyl 4-[N-(4-chlorobenzyl)-N-(phenylsulfonyl)glycyl]piperazine-1-carboxylate
CAS 433244-76-9C22H26ClN3O5S
N-(2-Fluorobenzyl)-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H26FN3O3S, CAS 499112-67-3
N-(2-Fluorobenzyl)-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 499112-67-3C21H26FN3O3S
N-Benzyl-4-bromo-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H24BrN3O3S, CAS 433241-31-7
N-Benzyl-4-bromo-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 433241-31-7C20H24BrN3O3S
N-Benzyl-4-methoxy-3-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C22H29N3O4S, CAS 823825-49-6
N-Benzyl-4-methoxy-3-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 823825-49-6C22H29N3O4S
N-[(2-Chloro-6-fluorophenyl)methyl]-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H25ClFN3O3S, CAS 444778-26-1
N-[(2-Chloro-6-fluorophenyl)methyl]-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 444778-26-1C21H25ClFN3O3S
N-[(4-Chlorophenyl)methyl]-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H26ClN3O3S, CAS 593243-76-6
N-[(4-Chlorophenyl)methyl]-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 593243-76-6C21H26ClN3O3S
N-[(3-Chlorophenyl)methyl]-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H26ClN3O3S, CAS 446249-79-2
N-[(3-Chlorophenyl)methyl]-4-methyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 446249-79-2C21H26ClN3O3S
4-Chloro-N-(2-methylbenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C21H26ClN3O3S, CAS 693254-11-4
4-Chloro-N-(2-methylbenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 693254-11-4C21H26ClN3O3S
N-Benzyl-2,5-dichloro-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23Cl2N3O3S, CAS 431885-25-5
N-Benzyl-2,5-dichloro-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 431885-25-5C20H23Cl2N3O3S
4-Chloro-N-(2-chlorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23Cl2N3O3S, CAS 431930-44-8
4-Chloro-N-(2-chlorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 431930-44-8C20H23Cl2N3O3S
N-[(4-Bromophenyl)methyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H24BrN3O3S, CAS 432019-19-7
N-[(4-Bromophenyl)methyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 432019-19-7C20H24BrN3O3S
N-(2,4-Dichlorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23Cl2N3O3S, CAS 431908-12-2
N-(2,4-Dichlorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 431908-12-2C20H23Cl2N3O3S
Ethyl 4-[N-(4-bromobenzyl)-N-(phenylsulfonyl)glycyl]piperazine-1-carboxylate chemical structure, C22H26BrN3O5S, CAS 440098-36-2
Ethyl 4-[N-(4-bromobenzyl)-N-(phenylsulfonyl)glycyl]piperazine-1-carboxylate
CAS 440098-36-2C22H26BrN3O5S
4-Chloro-N-(2-fluorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23ClFN3O3S, CAS 593255-81-3
4-Chloro-N-(2-fluorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 593255-81-3C20H23ClFN3O3S
N-[(3,4-Dichlorophenyl)methyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23Cl2N3O3S, CAS 434294-94-7
N-[(3,4-Dichlorophenyl)methyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 434294-94-7C20H23Cl2N3O3S
Ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-(2-fluorobenzyl)glycyl}piperazine-1-carboxylate chemical structure, C22H25ClFN3O5S, CAS 593255-82-4
Ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-(2-fluorobenzyl)glycyl}piperazine-1-carboxylate
CAS 593255-82-4C22H25ClFN3O5S
4-Chloro-N-(2,6-dichlorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H22Cl3N3O3S, CAS 593256-01-0
4-Chloro-N-(2,6-dichlorobenzyl)-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 593256-01-0C20H22Cl3N3O3S
Ethyl 4-{N-(4-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]glycyl}-1-piperazinecarboxylate chemical structure, C23H28ClN3O5S, CAS 592467-70-4
Ethyl 4-{N-(4-chlorobenzyl)-N-[(4-methylphenyl)sulfonyl]glycyl}-1-piperazinecarboxylate
CAS 592467-70-4C23H28ClN3O5S
4-Chloro-N-[(4-fluorophenyl)methyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide chemical structure, C20H23ClFN3O3S, CAS 510718-14-6
4-Chloro-N-[(4-fluorophenyl)methyl]-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide
CAS 510718-14-6C20H23ClFN3O3S
Ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-(4-fluorobenzyl)glycyl}piperazine-1-carboxylate chemical structure, C22H25ClFN3O5S, CAS 592467-18-0
Ethyl 4-{N-[(4-chlorophenyl)sulfonyl]-N-(4-fluorobenzyl)glycyl}piperazine-1-carboxylate
CAS 592467-18-0C22H25ClFN3O5S
Ethyl 4-{N-benzyl-N-[(4-methoxy-3-methylphenyl)sulfonyl]glycyl}-1-piperazinecarboxylate chemical structure, C24H31N3O6S, CAS 714206-07-2
Ethyl 4-{N-benzyl-N-[(4-methoxy-3-methylphenyl)sulfonyl]glycyl}-1-piperazinecarboxylate
CAS 714206-07-2C24H31N3O6S