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Murcko scaffold

Ring system with 3 rings and 25 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
11
With full pages
4
Scaffold SMILES

O=C(NC(Nc1ccccc1)C(=O)c1ccccc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC(Nc1ccccc1)C(=O)c1ccccc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N-{1-[(4-Bromophenyl)amino]-2-oxo-2-phenylethyl}benzamide chemical structure, C21H17BrN2O2, CAS 302821-83-6
N-{1-[(4-Bromophenyl)amino]-2-oxo-2-phenylethyl}benzamide
CAS 302821-83-6C21H17BrN2O2
4-Methoxy-N-{2-oxo-2-phenyl-1-[(4-sulfamoylphenyl)amino]ethyl}benzamide chemical structure, C22H21N3O5S, CAS 332885-72-0
4-Methoxy-N-{2-oxo-2-phenyl-1-[(4-sulfamoylphenyl)amino]ethyl}benzamide
CAS 332885-72-0C22H21N3O5S
N-{1-[(3,4-Dimethylphenyl)amino]-2-oxo-2-phenylethyl}benzamide chemical structure, C23H22N2O2, CAS 303016-74-2
N-{1-[(3,4-Dimethylphenyl)amino]-2-oxo-2-phenylethyl}benzamide
CAS 303016-74-2C23H22N2O2
4-Chloro-N-{1-[(2-fluorophenyl)amino]-2-oxo-2-phenylethyl}benzamide chemical structure, C21H16ClFN2O2, CAS 324542-65-6
4-Chloro-N-{1-[(2-fluorophenyl)amino]-2-oxo-2-phenylethyl}benzamide
CAS 324542-65-6C21H16ClFN2O2
4-Methyl-N-{1-[(3-methylphenyl)amino]-2-oxo-2-phenylethyl}benzamide chemical structure, C23H22N2O2, CAS 303016-36-6
4-Methyl-N-{1-[(3-methylphenyl)amino]-2-oxo-2-phenylethyl}benzamide
CAS 303016-36-6C23H22N2O2
N-{1-[(2,5-Dimethylphenyl)amino]-2-oxo-2-phenylethyl}-4-methylbenzamide chemical structure, C24H24N2O2, CAS 303016-72-0
N-{1-[(2,5-Dimethylphenyl)amino]-2-oxo-2-phenylethyl}-4-methylbenzamide
CAS 303016-72-0C24H24N2O2
N-{1-[(4-Chlorophenyl)amino]-2-oxo-2-phenylethyl}-4-methoxybenzamide chemical structure, C22H19ClN2O3, CAS 303016-34-4
N-{1-[(4-Chlorophenyl)amino]-2-oxo-2-phenylethyl}-4-methoxybenzamide
CAS 303016-34-4C22H19ClN2O3
N-{1-[(2-Fluorophenyl)amino]-2-oxo-2-phenylethyl}benzamide chemical structure, C21H17FN2O2, CAS 329218-56-6
N-{1-[(2-Fluorophenyl)amino]-2-oxo-2-phenylethyl}benzamide
CAS 329218-56-6C21H17FN2O2
N-(1-Anilino-2-oxo-2-phenylethyl)-4-methoxybenzamide chemical structure, C22H20N2O3, CAS 303016-42-4
N-(1-Anilino-2-oxo-2-phenylethyl)-4-methoxybenzamide
CAS 303016-42-4C22H20N2O3
N-{1-[(2,5-Dichlorophenyl)amino]-2-oxo-2-phenylethyl}-4-methoxybenzamide chemical structure, C22H18Cl2N2O3, CAS 303016-63-9
N-{1-[(2,5-Dichlorophenyl)amino]-2-oxo-2-phenylethyl}-4-methoxybenzamide
CAS 303016-63-9C22H18Cl2N2O3
4-Fluoro-N-{1-[(2-fluorophenyl)amino]-2-oxo-2-phenylethyl}benzamide chemical structure, C21H16F2N2O2, CAS 518349-29-6
4-Fluoro-N-{1-[(2-fluorophenyl)amino]-2-oxo-2-phenylethyl}benzamide
CAS 518349-29-6C21H16F2N2O2