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Murcko scaffold

Ring system with 3 rings and 26 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
26
Chemicals
7
With full pages
3
Scaffold SMILES

O=C(C(Cc1ccccc1)NS(=O)(=O)c1ccccc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(C(Cc1ccccc1)NS(=O)(=O)c1ccccc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Piperidine, 1-(3-(3-(aminoiminomethyl)phenyl)-2-(((4-methylphenyl)sulfonyl)amino)-1-oxopropyl)- chemical structure, C22H28N4O3S, CAS 73438-63-8
Piperidine, 1-(3-(3-(aminoiminomethyl)phenyl)-2-(((4-methylphenyl)sulfonyl)amino)-1-oxopropyl)-
CAS 73438-63-8C22H28N4O3S
N(alpha)-(4-Toluenesulfonyl)-4-guanidinophenylalanylpiperidine chemical structure, C22H29N5O3S, CAS 137623-46-2
N(alpha)-(4-Toluenesulfonyl)-4-guanidinophenylalanylpiperidine
CAS 137623-46-2C22H29N5O3S
4-Tapap chemical structure, C22H28N4O3S, CAS 73438-62-7
4-Tapap
CAS 73438-62-7C22H28N4O3S
3-[(2s)-2-{[(4-Methylphenyl)sulfonyl]amino}-3-Oxo-3-Piperidin-1-Ylpropyl]benzenecarboximidamide chemical structure, C22H28N4O3S, CAS 80457-09-6
3-[(2s)-2-{[(4-Methylphenyl)sulfonyl]amino}-3-Oxo-3-Piperidin-1-Ylpropyl]benzenecarboximidamide
CAS 80457-09-6C22H28N4O3S
Benzenesulfonamide, p-amidino-N-(alpha-(piperidinocarbonyl)phenethyl)- chemical structure, C21H26N4O3S, CAS 92953-62-3
Benzenesulfonamide, p-amidino-N-(alpha-(piperidinocarbonyl)phenethyl)-
CAS 92953-62-3C21H26N4O3S
p-Toluenesulfonamide, N-(p-amino-alpha-(piperidinocarbonyl)phenethyl)- chemical structure, C21H27N3O3S, CAS 109006-04-4
p-Toluenesulfonamide, N-(p-amino-alpha-(piperidinocarbonyl)phenethyl)-
CAS 109006-04-4C21H27N3O3S
(1-(Tosyl-L-phenylalanyl)piperidine-4-carbonyl)glycine chemical structure, C24H29N3O6S, CAS 956942-46-4
(1-(Tosyl-L-phenylalanyl)piperidine-4-carbonyl)glycine
CAS 956942-46-4C24H29N3O6S