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Murcko scaffold

Ring system with 3 rings and 18 atoms

18 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
18
With full pages
1
Scaffold SMILES

c1ccc(CCN2CCc3ccccc3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CCN2CCc3ccccc3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 18 of 18 chemicals

Veradoline chemical structure, C20H26N2O2, CAS 79201-80-2
Veradoline
CAS 79201-80-2C20H26N2O2
Ethanol, 2-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinolin-2-yl)-1-(3-nitrophenyl)- chemical structure, C20H24N2O5, CAS 374704-73-1
Ethanol, 2-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-methylisoquinolin-2-yl)-1-(3-nitrophenyl)-
CAS 374704-73-1C20H24N2O5
Veradoline hydrochloride chemical structure, C20H28Cl2N2O2, CAS 76448-47-0
Veradoline hydrochloride
CAS 76448-47-0C20H28Cl2N2O2
2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylethanol chemical structure, C19H23NO3, CAS 790998-23-1
2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-phenylethanol
CAS 790998-23-1C19H23NO3
Isoquinoline, 1,2,3,4-tetrahydro-2-(p-chlorophenethyl)-6,7-dimethoxy-1-methyl-, fumarate chemical structure, C24H28ClNO6, CAS 1872-81-7
Isoquinoline, 1,2,3,4-tetrahydro-2-(p-chlorophenethyl)-6,7-dimethoxy-1-methyl-, fumarate
CAS 1872-81-7C24H28ClNO6
4-(2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)benzenamine chemical structure, C19H24N2O2, CAS 82925-02-8
4-(2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)benzenamine
CAS 82925-02-8C19H24N2O2
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[2-(4-nitrophenyl)ethyl]isoquinoline chemical structure, C19H22N2O4, CAS 82925-01-7
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[2-(4-nitrophenyl)ethyl]isoquinoline
CAS 82925-01-7C19H22N2O4
I+/--(4-Fluorophenyl)-3,4-dihydro-2(1H)-isoquinolineethanamine chemical structure, C17H19FN2, CAS 953905-90-3
I+/--(4-Fluorophenyl)-3,4-dihydro-2(1H)-isoquinolineethanamine
CAS 953905-90-3C17H19FN2
3,4-Dihydro-I+/--(4-methoxyphenyl)-2(1H)-isoquinolineethanamine chemical structure, C18H22N2O, CAS 954253-22-6
3,4-Dihydro-I+/--(4-methoxyphenyl)-2(1H)-isoquinolineethanamine
CAS 954253-22-6C18H22N2O
Veradoline monohydrochloride chemical structure, C20H27ClN2O2, CAS 82924-70-7
Veradoline monohydrochloride
CAS 82924-70-7C20H27ClN2O2
2-Phenethyl-3,4-dihydro-1H-isoquinoline hydrochloride chemical structure, C17H20ClN, CAS 7467-63-2
2-Phenethyl-3,4-dihydro-1H-isoquinoline hydrochloride
CAS 7467-63-2C17H20ClN
2-(3,4-Dihydro-1H-isoquinolin-2-yl)-1-phenyl-ethanol chemical structure, C17H20ClNO, CAS 7505-78-4
2-(3,4-Dihydro-1H-isoquinolin-2-yl)-1-phenyl-ethanol
CAS 7505-78-4C17H20ClNO
Antidepressant agent 5 chemical structure, C20H25NO3, CAS 1071049-42-7
Antidepressant agent 5
CAS 1071049-42-7C20H25NO3
4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]benzenamine-d4 chemical structure, C19H24N2O2, CAS 1794883-59-2
4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]benzenamine-d4
CAS 1794883-59-2C19H24N2O2
2-(4-Chlorophenethyl)-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol chemical structure, C18H20ClNO2, CAS 1395084-80-6
2-(4-Chlorophenethyl)-7-methoxy-1,2,3,4-tetrahydroisoquinolin-6-ol
CAS 1395084-80-6C18H20ClNO2
2-[1-(4-Hydroxyphenyl)propan-2-yl]-3,4-dihydro-1H-isoquinoline-4,6,8-triol chemical structure, C18H21NO4, CAS 161040-25-1
2-[1-(4-Hydroxyphenyl)propan-2-yl]-3,4-dihydro-1H-isoquinoline-4,6,8-triol
CAS 161040-25-1C18H21NO4
N-{2-[2-(3-Chlorophenyl)ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}acetamide hydrochloride chemical structure, C19H22Cl2N2O, CAS 2624129-92-4
N-{2-[2-(3-Chlorophenyl)ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}acetamide hydrochloride
CAS 2624129-92-4C19H22Cl2N2O
N-{2-[2-(3-Chloro-4-fluorophenyl)ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}acetamide chemical structure, C19H20ClFN2O, CAS 2624139-59-7
N-{2-[2-(3-Chloro-4-fluorophenyl)ethyl]-1,2,3,4-tetrahydroisoquinolin-6-yl}acetamide
CAS 2624139-59-7C19H20ClFN2O