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Murcko scaffold

Ring system with 3 rings and 21 atoms

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
20
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2c(=O)[nH]c(=O)[nH]c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc2c(=O)[nH]c(=O)[nH]c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

N-(3,4-Difluorophenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H19F2N3O3, CAS 892289-01-9
N-(3,4-Difluorophenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892289-01-9C20H19F2N3O3
N-(4-Fluorophenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H20FN3O3, CAS 892289-09-7
N-(4-Fluorophenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892289-09-7C20H20FN3O3
3-(2-Methoxyethyl)-N-(4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C19H19N3O5, CAS 892290-60-7
3-(2-Methoxyethyl)-N-(4-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892290-60-7C19H19N3O5
N-(3-Acetylphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H19N3O5, CAS 892259-78-8
N-(3-Acetylphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892259-78-8C20H19N3O5
N-(3,4-Dimethoxyphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O5, CAS 892260-66-1
N-(3,4-Dimethoxyphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-66-1C22H25N3O5
N-(3,5-Dimethylphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O3, CAS 892260-82-1
N-(3,5-Dimethylphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-82-1C22H25N3O3
N-(3,5-Dimethoxyphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O5, CAS 892260-90-1
N-(3,5-Dimethoxyphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-90-1C22H25N3O5
N-(3,4-Dimethylphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O3, CAS 892260-74-1
N-(3,4-Dimethylphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-74-1C22H25N3O3
N-(3-Chloro-4-methoxyphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C19H18ClN3O5, CAS 892260-10-5
N-(3-Chloro-4-methoxyphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-10-5C19H18ClN3O5
N-(3,4-Dimethylphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H21N3O4, CAS 958584-78-6
N-(3,4-Dimethylphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 958584-78-6C20H21N3O4
N-(3,4-Dimethoxyphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H21N3O6, CAS 892260-02-5
N-(3,4-Dimethoxyphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-02-5C20H21N3O6
N-(3,5-Dimethoxyphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H21N3O6, CAS 931722-21-3
N-(3,5-Dimethoxyphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 931722-21-3C20H21N3O6
N-(3,5-Dimethylphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H21N3O4, CAS 892260-18-3
N-(3,5-Dimethylphenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-18-3C20H21N3O4
3-(2-Methoxyethyl)-2,4-dioxo-N-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C21H23N3O7, CAS 892290-52-7
3-(2-Methoxyethyl)-2,4-dioxo-N-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892290-52-7C21H23N3O7
N-(4-Methoxyphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C21H23N3O4, CAS 892289-25-7
N-(4-Methoxyphenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892289-25-7C21H23N3O4
2,4-Dioxo-3-pentyl-N-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C23H27N3O6, CAS 892289-17-7
2,4-Dioxo-3-pentyl-N-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892289-17-7C23H27N3O6
3-(2-Methoxyethyl)-N-(3-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C19H19N3O5, CAS 892260-42-3
3-(2-Methoxyethyl)-N-(3-methoxyphenyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-42-3C19H19N3O5
N-(3,4-Difluorophenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C18H15F2N3O4, CAS 892260-50-3
N-(3,4-Difluorophenyl)-3-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-50-3C18H15F2N3O4
N-(3-Fluorophenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C20H20FN3O3, CAS 892260-98-9
N-(3-Fluorophenyl)-2,4-dioxo-3-pentyl-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 892260-98-9C20H20FN3O3
N-(2,5-Dimethylphenyl)-3-ethyl-N-isopropyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide chemical structure, C22H25N3O3, CAS 1423778-04-4
N-(2,5-Dimethylphenyl)-3-ethyl-N-isopropyl-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
CAS 1423778-04-4C22H25N3O3