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Murcko scaffold

Ring system with 2 rings and 14 atoms

267 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
267
With full pages
9
Scaffold SMILES

O=C(c1cccnc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1cccnc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 267 chemicals

(2,6-Dichloro-5-fluoropyridin-3-yl)(piperidino)methanone chemical structure, C11H11Cl2FN2O, CAS 680217-87-2
(2,6-Dichloro-5-fluoropyridin-3-yl)(piperidino)methanone
CAS 680217-87-2C11H11Cl2FN2O
2-Chloro-5-(piperidin-1-ylcarbonyl)pyridine chemical structure, C11H13ClN2O, CAS 64614-48-8
2-Chloro-5-(piperidin-1-ylcarbonyl)pyridine
CAS 64614-48-8C11H13ClN2O
(2-Chloro-3-pyridinyl)(4-methyl-1-piperidinyl)-methanone chemical structure, C12H15ClN2O, CAS 353258-80-7
(2-Chloro-3-pyridinyl)(4-methyl-1-piperidinyl)-methanone
CAS 353258-80-7C12H15ClN2O
1-(Pyridine-3-carbonyl)piperidine-4-carboxylic acid chemical structure, C12H14N2O3, CAS 67691-57-0
1-(Pyridine-3-carbonyl)piperidine-4-carboxylic acid
CAS 67691-57-0C12H14N2O3
Piperidino{2-[(3,4,4-trifluoro-3-butenyl)sulfanyl]-3-pyridinyl}methanone chemical structure, C15H17F3N2OS, CAS 339106-90-0
Piperidino{2-[(3,4,4-trifluoro-3-butenyl)sulfanyl]-3-pyridinyl}methanone
CAS 339106-90-0C15H17F3N2OS
4-Methyl-1-(3-pyridinylcarbonyl)piperidine chemical structure, C12H16N2O, CAS 341516-52-7
4-Methyl-1-(3-pyridinylcarbonyl)piperidine
CAS 341516-52-7C12H16N2O
2-Chloro-5-(4-methylpiperidine-1-carbonyl)pyridine chemical structure, C12H15ClN2O, CAS 385407-85-2
2-Chloro-5-(4-methylpiperidine-1-carbonyl)pyridine
CAS 385407-85-2C12H15ClN2O
Ethyl 1-(3-pyridinylcarbonyl)-4-piperidinecarboxylate chemical structure, C14H18N2O3, CAS 189300-75-2
Ethyl 1-(3-pyridinylcarbonyl)-4-piperidinecarboxylate
CAS 189300-75-2C14H18N2O3
Ethyl 1-(2-chloropyridine-3-carbonyl)piperidine-4-carboxylate chemical structure, C14H17ClN2O3, CAS 565168-50-5
Ethyl 1-(2-chloropyridine-3-carbonyl)piperidine-4-carboxylate
CAS 565168-50-5C14H17ClN2O3
[2-Methyl-6-(trifluoromethyl)pyridin-3-yl](piperidino)methanone chemical structure, C13H15F3N2O, CAS 651006-70-1
[2-Methyl-6-(trifluoromethyl)pyridin-3-yl](piperidino)methanone
CAS 651006-70-1C13H15F3N2O
[1-(Pyridine-3-carbonyl)piperidin-3-yl]methanol chemical structure, C12H16N2O2, CAS 349096-78-2
[1-(Pyridine-3-carbonyl)piperidin-3-yl]methanol
CAS 349096-78-2C12H16N2O2
(2-Chloro-3-pyridinyl)(3-methyl-1-piperidinyl)-methanone chemical structure, C12H15ClN2O, CAS 560106-13-0
(2-Chloro-3-pyridinyl)(3-methyl-1-piperidinyl)-methanone
CAS 560106-13-0C12H15ClN2O
(6-Chloropyridin-3-yl)(2-methylpiperidin-1-yl)methanone chemical structure, C12H15ClN2O, CAS 385408-28-6
(6-Chloropyridin-3-yl)(2-methylpiperidin-1-yl)methanone
CAS 385408-28-6C12H15ClN2O
2,6-Dichloro-3-fluoro-5-[(3-methyl-1-piperidinyl)carbonyl]pyridine chemical structure, C12H13Cl2FN2O, CAS 724431-37-2
2,6-Dichloro-3-fluoro-5-[(3-methyl-1-piperidinyl)carbonyl]pyridine
CAS 724431-37-2C12H13Cl2FN2O
(5-Bromopyridin-3-yl)-(4-methylpiperidin-1-yl)methanone chemical structure, C12H15BrN2O, CAS 302953-14-6
(5-Bromopyridin-3-yl)-(4-methylpiperidin-1-yl)methanone
CAS 302953-14-6C12H15BrN2O
(2-Chloropyridin-3-yl)(piperidin-1-yl)methanone chemical structure, C11H13ClN2O, CAS 56149-33-8
(2-Chloropyridin-3-yl)(piperidin-1-yl)methanone
CAS 56149-33-8C11H13ClN2O
2-Chloro-5-(3-methylpiperidine-1-carbonyl)pyridine chemical structure, C12H15ClN2O, CAS 325738-95-2
2-Chloro-5-(3-methylpiperidine-1-carbonyl)pyridine
CAS 325738-95-2C12H15ClN2O
(2-Chloropyridin-3-yl)(2-ethylpiperidin-1-yl)methanone chemical structure, C13H17ClN2O, CAS 573993-66-5
(2-Chloropyridin-3-yl)(2-ethylpiperidin-1-yl)methanone
CAS 573993-66-5C13H17ClN2O
2-Chloro-5-[3-(trifluoromethyl)piperidine-1-carbonyl]pyridine chemical structure, C12H12ClF3N2O, CAS 385407-83-0
2-Chloro-5-[3-(trifluoromethyl)piperidine-1-carbonyl]pyridine
CAS 385407-83-0C12H12ClF3N2O
1-[(2-Chloro-3-pyridinyl)carbonyl]-2,6-dimethylpiperidine chemical structure, C13H17ClN2O, CAS 551911-59-2
1-[(2-Chloro-3-pyridinyl)carbonyl]-2,6-dimethylpiperidine
CAS 551911-59-2C13H17ClN2O
(2-Chloro-3-pyridinyl)(2-methyl-1-piperidinyl)-methanone chemical structure, C12H15ClN2O, CAS 438613-81-1
(2-Chloro-3-pyridinyl)(2-methyl-1-piperidinyl)-methanone
CAS 438613-81-1C12H15ClN2O
Piperidine, 1-[(2-chloro-6-methyl-3-pyridinyl)carbonyl]-2-methyl- chemical structure, C13H17ClN2O, CAS 613660-42-7
Piperidine, 1-[(2-chloro-6-methyl-3-pyridinyl)carbonyl]-2-methyl-
CAS 613660-42-7C13H17ClN2O
Piperidine, 1-[(6-methyl-3-pyridinyl)carbonyl]-4-propyl- chemical structure, C15H22N2O, CAS 613660-27-8
Piperidine, 1-[(6-methyl-3-pyridinyl)carbonyl]-4-propyl-
CAS 613660-27-8C15H22N2O
Piperidine, 2-ethyl-1-[(6-methyl-3-pyridinyl)carbonyl]- chemical structure, C14H20N2O, CAS 613660-25-6
Piperidine, 2-ethyl-1-[(6-methyl-3-pyridinyl)carbonyl]-
CAS 613660-25-6C14H20N2O