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Murcko scaffold

Ring system with 4 rings and 26 atoms

37 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
37
With full pages
1
Scaffold SMILES

O=c1c(S(=O)(=O)c2ccccc2)c[nH]c2cc(N3CCOCC3)ccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(S(=O)(=O)c2ccccc2)c[nH]c2cc(N3CCOCC3)ccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

1-Ethyl-6-fluoro-7-morpholino-3-tosylquinolin-4(1H)-one chemical structure, C22H23FN2O4S, CAS 892762-58-2
1-Ethyl-6-fluoro-7-morpholino-3-tosylquinolin-4(1H)-one
CAS 892762-58-2C22H23FN2O4S
3-((2,5-Dimethylphenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one chemical structure, C24H27FN2O4S, CAS 892781-59-8
3-((2,5-Dimethylphenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one
CAS 892781-59-8C24H27FN2O4S
1-Butyl-6-fluoro-7-morpholino-3-(m-tolylsulfonyl)quinolin-4(1H)-one chemical structure, C24H27FN2O4S, CAS 892785-83-0
1-Butyl-6-fluoro-7-morpholino-3-(m-tolylsulfonyl)quinolin-4(1H)-one
CAS 892785-83-0C24H27FN2O4S
3-((3,5-Dimethylphenyl)sulfonyl)-1-ethyl-6-fluoro-7-morpholinoquinolin-4(1H)-one chemical structure, C23H25FN2O4S, CAS 892788-71-5
3-((3,5-Dimethylphenyl)sulfonyl)-1-ethyl-6-fluoro-7-morpholinoquinolin-4(1H)-one
CAS 892788-71-5C23H25FN2O4S
3-((3-Chlorophenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one chemical structure, C22H22ClFN2O4S, CAS 892757-96-9
3-((3-Chlorophenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one
CAS 892757-96-9C22H22ClFN2O4S
3-((4-Ethylphenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one chemical structure, C22H23FN2O4S, CAS 892768-71-7
3-((4-Ethylphenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one
CAS 892768-71-7C22H23FN2O4S
1-Ethyl-3-((4-ethylphenyl)sulfonyl)-6-fluoro-7-morpholinoquinolin-4(1H)-one chemical structure, C23H25FN2O4S, CAS 892769-52-7
1-Ethyl-3-((4-ethylphenyl)sulfonyl)-6-fluoro-7-morpholinoquinolin-4(1H)-one
CAS 892769-52-7C23H25FN2O4S
1-Butyl-3-(4-ethylbenzenesulfonyl)-6-fluoro-7-(morpholin-4-yl)-1,4-dihydroquinolin-4-one chemical structure, C25H29FN2O4S, CAS 892771-18-5
1-Butyl-3-(4-ethylbenzenesulfonyl)-6-fluoro-7-(morpholin-4-yl)-1,4-dihydroquinolin-4-one
CAS 892771-18-5C25H29FN2O4S
6-Fluoro-3-(4-methoxybenzenesulfonyl)-1-methyl-7-(morpholin-4-yl)-1,4-dihydroquinolin-4-one chemical structure, C21H21FN2O5S, CAS 892772-06-4
6-Fluoro-3-(4-methoxybenzenesulfonyl)-1-methyl-7-(morpholin-4-yl)-1,4-dihydroquinolin-4-one
CAS 892772-06-4C21H21FN2O5S
1-Butyl-6-fluoro-3-((4-methoxyphenyl)sulfonyl)-7-morpholinoquinolin-4(1H)-one chemical structure, C24H27FN2O5S, CAS 892774-33-3
1-Butyl-6-fluoro-3-((4-methoxyphenyl)sulfonyl)-7-morpholinoquinolin-4(1H)-one
CAS 892774-33-3C24H27FN2O5S
3-((4-Chlorophenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one chemical structure, C20H18ClFN2O4S, CAS 892774-97-9
3-((4-Chlorophenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one
CAS 892774-97-9C20H18ClFN2O4S
3-((4-Chlorophenyl)sulfonyl)-1-ethyl-6-fluoro-7-morpholinoquinolin-4(1H)-one chemical structure, C21H20ClFN2O4S, CAS 892775-77-8
3-((4-Chlorophenyl)sulfonyl)-1-ethyl-6-fluoro-7-morpholinoquinolin-4(1H)-one
CAS 892775-77-8C21H20ClFN2O4S
3-((2,4-Dimethylphenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one chemical structure, C22H23FN2O4S, CAS 892778-16-4
3-((2,4-Dimethylphenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one
CAS 892778-16-4C22H23FN2O4S
6-Fluoro-7-morpholino-1-propyl-3-tosylquinolin-4(1H)-one chemical structure, C23H25FN2O4S, CAS 892763-26-7
6-Fluoro-7-morpholino-1-propyl-3-tosylquinolin-4(1H)-one
CAS 892763-26-7C23H25FN2O4S
6-Fluoro-1-methyl-7-morpholino-3-tosylquinolin-4(1H)-one chemical structure, C21H21FN2O4S, CAS 892761-91-0
6-Fluoro-1-methyl-7-morpholino-3-tosylquinolin-4(1H)-one
CAS 892761-91-0C21H21FN2O4S
6-Fluoro-3-((4-methoxyphenyl)sulfonyl)-7-morpholino-1-propylquinolin-4(1H)-one chemical structure, C23H25FN2O5S, CAS 892773-78-3
6-Fluoro-3-((4-methoxyphenyl)sulfonyl)-7-morpholino-1-propylquinolin-4(1H)-one
CAS 892773-78-3C23H25FN2O5S
1-Butyl-3-((3,5-dimethylphenyl)sulfonyl)-6-fluoro-7-morpholinoquinolin-4(1H)-one chemical structure, C25H29FN2O4S, CAS 931698-24-7
1-Butyl-3-((3,5-dimethylphenyl)sulfonyl)-6-fluoro-7-morpholinoquinolin-4(1H)-one
CAS 931698-24-7C25H29FN2O4S
3-(Benzenesulfonyl)-1-butyl-6-fluoro-7-(morpholin-4-yl)-1,4-dihydroquinolin-4-one chemical structure, C23H25FN2O4S, CAS 892759-63-6
3-(Benzenesulfonyl)-1-butyl-6-fluoro-7-(morpholin-4-yl)-1,4-dihydroquinolin-4-one
CAS 892759-63-6C23H25FN2O4S
1-Butyl-6-fluoro-7-morpholino-3-tosylquinolin-4(1H)-one chemical structure, C24H27FN2O4S, CAS 892764-00-0
1-Butyl-6-fluoro-7-morpholino-3-tosylquinolin-4(1H)-one
CAS 892764-00-0C24H27FN2O4S
3-((3,4-Dimethylphenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one chemical structure, C22H23FN2O4S, CAS 892765-60-5
3-((3,4-Dimethylphenyl)sulfonyl)-6-fluoro-1-methyl-7-morpholinoquinolin-4(1H)-one
CAS 892765-60-5C22H23FN2O4S
3-((3,4-Dimethylphenyl)sulfonyl)-1-ethyl-6-fluoro-7-morpholinoquinolin-4(1H)-one chemical structure, C23H25FN2O4S, CAS 892766-24-4
3-((3,4-Dimethylphenyl)sulfonyl)-1-ethyl-6-fluoro-7-morpholinoquinolin-4(1H)-one
CAS 892766-24-4C23H25FN2O4S
3-((3,4-Dimethylphenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one chemical structure, C24H27FN2O4S, CAS 892767-04-3
3-((3,4-Dimethylphenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one
CAS 892767-04-3C24H27FN2O4S
3-((4-Ethylphenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one chemical structure, C24H27FN2O4S, CAS 892770-31-9
3-((4-Ethylphenyl)sulfonyl)-6-fluoro-7-morpholino-1-propylquinolin-4(1H)-one
CAS 892770-31-9C24H27FN2O4S
1-Ethyl-6-fluoro-3-((4-methoxyphenyl)sulfonyl)-7-morpholinoquinolin-4(1H)-one chemical structure, C22H23FN2O5S, CAS 892772-92-8
1-Ethyl-6-fluoro-3-((4-methoxyphenyl)sulfonyl)-7-morpholinoquinolin-4(1H)-one
CAS 892772-92-8C22H23FN2O5S