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Murcko scaffold

5-[(1,3-Diphenylpyrazol-4-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one scaffold

485 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 25
Chemicals: 485
With full pages: 168

Scaffold SMILES

O=C1NC(=S)SC1=Cc1cn(-c2ccccc2)nc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 5-[(1,3-Diphenylpyrazol-4-yl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one page

Murcko scaffold O=C1NC(=S)SC1=Cc1cn(-c2ccccc2)nc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 485 chemicals

((5Z)-5-((3-(4-Ethoxy-3-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid chemical structure, C23H18FN3O4S2, CAS 623934-98-5

((5Z)-5-((3-(4-Ethoxy-3-fluorophenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid

CAS 623934-98-5C₂₃H₁₈FN₃O₄S₂

(5Z)-5-{[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C21H17N3O3S2, CAS 882218-76-0

(5Z)-5-{[3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-sulfanylidene-1,3-thiazolidin-4-one

CAS 882218-76-0C₂₁H₁₇N₃O₃S₂

3-[(5Z)-5-[[3-(4-Ethoxy-3-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid chemical structure, C25H23N3O4S2, CAS 381708-52-7

3-[(5Z)-5-[[3-(4-Ethoxy-3-methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid

CAS 381708-52-7C₂₅H₂₃N₃O₄S₂

(5Z)-5-({3-[3-Methyl-4-(2-methylpropoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C24H23N3O2S2, CAS 955963-12-9

(5Z)-5-({3-[3-Methyl-4-(2-methylpropoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one

CAS 955963-12-9C₂₄H₂₃N₃O₂S₂

(5Z)-5-{[3-(4-Methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-methyl-2-thioxo-1,3-thiazolidin-4-one chemical structure, C22H19N3O2S2, CAS 955896-12-5

(5Z)-5-{[3-(4-Methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-methyl-2-thioxo-1,3-thiazolidin-4-one

CAS 955896-12-5C₂₂H₁₉N₃O₂S₂

(5Z)-3-Methyl-5-({3-[4-(2-methylpropoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C24H23N3O2S2, CAS 955961-85-0

(5Z)-3-Methyl-5-({3-[4-(2-methylpropoxy)phenyl]-1-phenyl-1H-pyrazol-4-yl}methylidene)-2-thioxo-1,3-thiazolidin-4-one

CAS 955961-85-0C₂₄H₂₃N₃O₂S₂

(5Z)-3-Methyl-5-[[1-phenyl-3-(4-propan-2-yloxyphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C23H21N3O2S2, CAS 378755-92-1

(5Z)-3-Methyl-5-[[1-phenyl-3-(4-propan-2-yloxyphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

CAS 378755-92-1C₂₃H₂₁N₃O₂S₂

(5Z)-5-{[3-(3-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C21H17N3O2S2, CAS 1002008-30-1

(5Z)-5-{[3-(3-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one

CAS 1002008-30-1C₂₁H₁₇N₃O₂S₂

(5Z)-5-{[3-(3-Methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C20H15N3O2S2, CAS 1002008-32-3

(5Z)-5-{[3-(3-Methoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one

CAS 1002008-32-3C₂₀H₁₅N₃O₂S₂

(5Z)-5-{[3-(3-Chloro-4-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C21H16ClN3O2S2, CAS 956706-02-8

(5Z)-5-{[3-(3-Chloro-4-ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one

CAS 956706-02-8C₂₁H₁₆ClN₃O₂S₂

(5Z)-5-{[3-(4-Methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(2-methylpropyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C24H23N3OS2, CAS 313273-00-6

(5Z)-5-{[3-(4-Methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(2-methylpropyl)-2-thioxo-1,3-thiazolidin-4-one

CAS 313273-00-6C₂₄H₂₃N₃OS₂

2-[(5Z)-5-[[3-(4-Methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid chemical structure, C22H17N3O3S2, CAS 312746-15-9

2-[(5Z)-5-[[3-(4-Methylphenyl)-1-phenylpyrazol-4-yl]methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]acetic acid

CAS 312746-15-9C₂₂H₁₇N₃O₃S₂

(5E)-5-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C19H12ClN3OS2, CAS 955962-02-4

(5E)-5-{[3-(4-Chlorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one

CAS 955962-02-4C₁₉H₁₂ClN₃OS₂

5-(1,3-Diphenyl-1H-pyrazol-4-ylmethylene)-2-mercapto-thiazol-4-one chemical structure, C19H13N3OS2, CAS 380155-13-5

5-(1,3-Diphenyl-1H-pyrazol-4-ylmethylene)-2-mercapto-thiazol-4-one

CAS 380155-13-5C₁₉H₁₃N₃OS₂

5-((1,3-Diphenyl-1H-pyrazol-4-yl)methylene)-2-mercaptothiazol-4(5H)-one chemical structure, C19H13N3OS2, CAS 1452310-44-9

5-((1,3-Diphenyl-1H-pyrazol-4-yl)methylene)-2-mercaptothiazol-4(5H)-one

CAS 1452310-44-9C₁₉H₁₃N₃OS₂

(5Z)-5-{[3-(4-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-methyl-2-thioxo-1,3-thiazolidin-4-one chemical structure, C22H19N3O2S2, CAS 313272-62-7

(5Z)-5-{[3-(4-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-methyl-2-thioxo-1,3-thiazolidin-4-one

CAS 313272-62-7C₂₂H₁₉N₃O₂S₂

(5Z)-5-{[3-(4-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(propan-2-yl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C24H23N3O2S2, CAS 312314-55-9

(5Z)-5-{[3-(4-Ethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(propan-2-yl)-2-thioxo-1,3-thiazolidin-4-one

CAS 312314-55-9C₂₄H₂₃N₃O₂S₂

3-(1-Methylethyl)-5-[[3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene]-2-thioxo-4-Thiazolidinone chemical structure, C23H21N3OS2, CAS 312601-82-4

3-(1-Methylethyl)-5-[[3-(4-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene]-2-thioxo-4-Thiazolidinone

CAS 312601-82-4C₂₃H₂₁N₃OS₂

(5Z)-5-{[3-(4-Isobutoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C23H21N3O2S2, CAS 956047-12-4

(5Z)-5-{[3-(4-Isobutoxyphenyl)-1-phenyl-1H-pyrazol-4-yl]methylene}-2-thioxo-1,3-thiazolidin-4-one

CAS 956047-12-4C₂₃H₂₁N₃O₂S₂

4-[(5Z)-5-{[3-(4-Methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid chemical structure, C25H23N3O4S2, CAS 955899-71-5

4-[(5Z)-5-{[3-(4-Methoxy-2-methylphenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]butanoic acid

CAS 955899-71-5C₂₅H₂₃N₃O₄S₂

(5Z)-5-{[1-Phenyl-3-(3-propoxyphenyl)-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one chemical structure, C22H19N3O2S2, CAS 1010871-75-6

(5Z)-5-{[1-Phenyl-3-(3-propoxyphenyl)-1H-pyrazol-4-yl]methylidene}-2-thioxo-1,3-thiazolidin-4-one

CAS 1010871-75-6C₂₂H₁₉N₃O₂S₂

(5Z)-5-[[1-Phenyl-3-(4-prop-2-enoxyphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one chemical structure, C22H17N3O2S2, CAS 380577-95-7

(5Z)-5-[[1-Phenyl-3-(4-prop-2-enoxyphenyl)pyrazol-4-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one

CAS 380577-95-7C₂₂H₁₇N₃O₂S₂

(5Z)-5-{[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(3-methoxypropyl)-2-thioxo-1,3-thiazolidin-4-one chemical structure, C23H20FN3O2S2, CAS 313273-20-0

(5Z)-5-{[3-(4-Fluorophenyl)-1-phenyl-1H-pyrazol-4-yl]methylidene}-3-(3-methoxypropyl)-2-thioxo-1,3-thiazolidin-4-one

CAS 313273-20-0C₂₃H₂₀FN₃O₂S₂

(5-((3-(4-Isobutoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid chemical structure, C25H23N3O4S2, CAS 955972-94-8

(5-((3-(4-Isobutoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl)acetic acid

CAS 955972-94-8C₂₅H₂₃N₃O₄S₂