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Murcko scaffold

1-Cyclopentylpyrimidine-2,4(1H,3H)-dione scaffold

77 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
77
With full pages
7
Scaffold SMILES

O=c1ccn(C2CCCC2)c(=O)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Cyclopentylpyrimidine-2,4(1H,3H)-dione page
Murcko scaffold O=c1ccn(C2CCCC2)c(=O)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 77 chemicals

5-Fluoro-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione chemical structure, C10H13FN2O4, CAS 78336-03-5
5-Fluoro-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione
CAS 78336-03-5C10H13FN2O4
Carbocyclic 2'-deoxy-5-ethyluridine chemical structure, C12H18N2O4, CAS 98736-93-7
Carbocyclic 2'-deoxy-5-ethyluridine
CAS 98736-93-7C12H18N2O4
Carbocyclic 2'-deoxy-5-ethynyluridine chemical structure, C12H14N2O4, CAS 98736-95-9
Carbocyclic 2'-deoxy-5-ethynyluridine
CAS 98736-95-9C12H14N2O4
Carbathymidine chemical structure, C11H16N2O4, CAS 114884-15-0
Carbathymidine
CAS 114884-15-0C11H16N2O4
N(1)-Cyclopentyl-5-nitropyrimidine-2,4-dione chemical structure, C9H11N3O4, CAS 137487-63-9
N(1)-Cyclopentyl-5-nitropyrimidine-2,4-dione
CAS 137487-63-9C9H11N3O4
1-((1,2,3,4)-2-Fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-5-methyl-2,4-(1H,3H)-pyrimidinedione chemical structure, C11H15FN2O4, CAS 110864-91-0
1-((1,2,3,4)-2-Fluoro-3-hydroxy-4-(hydroxymethyl)cyclopentyl)-5-methyl-2,4-(1H,3H)-pyrimidinedione
CAS 110864-91-0C11H15FN2O4
Uracil, 5-bromo-1-cyclopentyl-3,6-dimethyl- chemical structure, C11H15BrN2O2, CAS 31991-90-9
Uracil, 5-bromo-1-cyclopentyl-3,6-dimethyl-
CAS 31991-90-9C11H15BrN2O2
Uracil, 1-cyclopentyl-3,6-dimethyl-5-dimethylamino- chemical structure, C13H21N3O2, CAS 32150-44-0
Uracil, 1-cyclopentyl-3,6-dimethyl-5-dimethylamino-
CAS 32150-44-0C13H21N3O2
1-[2-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C11H16N2O4, CAS 78795-26-3
1-[2-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-methylpyrimidine-2,4(1H,3H)-dione
CAS 78795-26-3C11H16N2O4
1-[(1R,3S,4R)-3-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-methyl-pyrimidine-2,4-dione chemical structure, C11H16N2O4, CAS 61849-27-2
1-[(1R,3S,4R)-3-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-methyl-pyrimidine-2,4-dione
CAS 61849-27-2C11H16N2O4
1-[3-Hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione chemical structure, C10H14N2O4, CAS 62102-28-7
1-[3-Hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione
CAS 62102-28-7C10H14N2O4
1-[2,3-Dihydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione chemical structure, C10H14N2O5
1-[2,3-Dihydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione
C10H14N2O5
1-[2,3-Dihydroxy-4-(hydroxymethyl)cyclopentyl]-5-methylpyrimidine-2,4(1H,3H)-dione chemical structure, C11H16N2O5, CAS 78795-27-4
1-[2,3-Dihydroxy-4-(hydroxymethyl)cyclopentyl]-5-methylpyrimidine-2,4(1H,3H)-dione
CAS 78795-27-4C11H16N2O5
1-[2-Hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione chemical structure, C10H14N2O4, CAS 62102-31-2
1-[2-Hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione
CAS 62102-31-2C10H14N2O4
5-Fluoro-1-[2-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione chemical structure, C10H13FN2O4, CAS 78336-04-6
5-Fluoro-1-[2-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione
CAS 78336-04-6C10H13FN2O4
1-[2,3-Dihydroxy-4-(hydroxymethyl)cyclopentyl]-5-fluoropyrimidine-2,4-dione chemical structure, C10H13FN2O5, CAS 78336-05-7
1-[2,3-Dihydroxy-4-(hydroxymethyl)cyclopentyl]-5-fluoropyrimidine-2,4-dione
CAS 78336-05-7C10H13FN2O5
5-Bromo-1-[(1S,2S,4R)-2-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione chemical structure, C10H13BrN2O4, CAS 83983-96-4
5-Bromo-1-[(1S,2S,4R)-2-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4(1H,3H)-dione
CAS 83983-96-4C10H13BrN2O4
5-Bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione chemical structure, C10H13BrN2O4, CAS 83967-02-6
5-Bromo-1-[3-hydroxy-4-(hydroxymethyl)cyclopentyl]pyrimidine-2,4-dione
CAS 83967-02-6C10H13BrN2O4
1-[3-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-(methylamino)pyrimidine-2,4-dione chemical structure, C11H17N3O4, CAS 83967-05-9
1-[3-Hydroxy-4-(hydroxymethyl)cyclopentyl]-5-(methylamino)pyrimidine-2,4-dione
CAS 83967-05-9C11H17N3O4
F-carbocyclic-AZT chemical structure, C11H14FN5O3, CAS 127530-13-6
F-carbocyclic-AZT
CAS 127530-13-6C11H14FN5O3
1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate chemical structure, C11H17FN5O12P3, CAS 127753-53-1
1-(4-Azido-2-fluoro-3-methoxycyclopentyl)thymine-triphosphate
CAS 127753-53-1C11H17FN5O12P3
F'-dd-carbo-T chemical structure, C11H15FN2O3, CAS 127530-14-7
F'-dd-carbo-T
CAS 127530-14-7C11H15FN2O3
2-F-3-MeOCyclopentylTTP chemical structure, C11H18FN2O12P3, CAS 137767-64-7
2-F-3-MeOCyclopentylTTP
CAS 137767-64-7C11H18FN2O12P3
Carbocyclic-3'-deoxythymidine chemical structure, C11H16N2O3, CAS 117957-63-8
Carbocyclic-3'-deoxythymidine
CAS 117957-63-8C11H16N2O3