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Murcko scaffold

Ring system with 3 rings and 19 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
8
With full pages
5
Scaffold SMILES

O=C(c1conc1-c1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1conc1-c1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

(4-Ethyl-piperazin-1-yl)-(5-methyl-3-phenyl-isoxazol-4-yl)-methanone chemical structure, C17H21N3O2, CAS 420844-89-9
(4-Ethyl-piperazin-1-yl)-(5-methyl-3-phenyl-isoxazol-4-yl)-methanone
CAS 420844-89-9C17H21N3O2
1-Methyl-4-[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]piperazine chemical structure, C16H19N3O2, CAS 313393-57-6
1-Methyl-4-[(5-methyl-3-phenyl-4-isoxazolyl)carbonyl]piperazine
CAS 313393-57-6C16H19N3O2
1-[(5-Methyl-3-phenyl-4-isoxazolyl)carbonyl]piperazine chemical structure, C15H17N3O2, CAS 124953-38-4
1-[(5-Methyl-3-phenyl-4-isoxazolyl)carbonyl]piperazine
CAS 124953-38-4C15H17N3O2
[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]-(4-methylpiperazin-1-yl)methanone chemical structure, C16H17Cl2N3O2, CAS 349131-47-1
[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]-(4-methylpiperazin-1-yl)methanone
CAS 349131-47-1C16H17Cl2N3O2
3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl 4-ethylpiperazinyl ketone chemical structure, C17H19Cl2N3O2, CAS 354536-83-7
3-(2,6-Dichlorophenyl)-5-methylisoxazol-4-yl 4-ethylpiperazinyl ketone
CAS 354536-83-7C17H19Cl2N3O2
4-[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]piperazine-1-carbaldehyde chemical structure, C16H16ClN3O3, CAS 866152-61-6
4-[3-(2-Chlorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]piperazine-1-carbaldehyde
CAS 866152-61-6C16H16ClN3O3
3-(2-Chlorophenyl)-5-methylisoxazol-4-yl 4-prop-2-enylpiperazinyl ketone chemical structure, C18H20ClN3O2, CAS 915917-03-2
3-(2-Chlorophenyl)-5-methylisoxazol-4-yl 4-prop-2-enylpiperazinyl ketone
CAS 915917-03-2C18H20ClN3O2
5-Methyl-3-phenylisoxazol-4-yl 4-prop-2-enylpiperazinyl ketone chemical structure, C18H21N3O2, CAS 915898-51-0
5-Methyl-3-phenylisoxazol-4-yl 4-prop-2-enylpiperazinyl ketone
CAS 915898-51-0C18H21N3O2