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Murcko scaffold

3-Phenyl-1,2,4-thiadiazole scaffold

213 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
213
With full pages
42
Scaffold SMILES

c1ccc(-c2ncsn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1,2,4-thiadiazole page
Murcko scaffold c1ccc(-c2ncsn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 213 of 213 chemicals

5-Chloro-3-[4-(difluoromethyl)-3-fluorophenyl]-1,2,4-thiadiazole chemical structure, C9H4ClF3N2S, CAS 2172117-52-9
5-Chloro-3-[4-(difluoromethyl)-3-fluorophenyl]-1,2,4-thiadiazole
CAS 2172117-52-9C9H4ClF3N2S
5-Chloro-3-[4-(difluoromethyl)-3,5-dimethylphenyl]-1,2,4-thiadiazole chemical structure, C11H9ClF2N2S, CAS 2172273-28-6
5-Chloro-3-[4-(difluoromethyl)-3,5-dimethylphenyl]-1,2,4-thiadiazole
CAS 2172273-28-6C11H9ClF2N2S
3-(4-Methylphenyl)-1,2,4-thiadiazole-5-carbohydrazide chemical structure, C10H10N4OS, CAS 2138564-93-7
3-(4-Methylphenyl)-1,2,4-thiadiazole-5-carbohydrazide
CAS 2138564-93-7C10H10N4OS
5-Chloro-3-[4-(difluoromethyl)phenyl]-1,2,4-thiadiazole chemical structure, C9H5ClF2N2S, CAS 2171939-09-4
5-Chloro-3-[4-(difluoromethyl)phenyl]-1,2,4-thiadiazole
CAS 2171939-09-4C9H5ClF2N2S
tert-Butyl N-[3-(3-hydroxyphenyl)-1,2,4-thiadiazol-5-yl]carbamate chemical structure, C13H15N3O3S, CAS 2413903-92-9
tert-Butyl N-[3-(3-hydroxyphenyl)-1,2,4-thiadiazol-5-yl]carbamate
CAS 2413903-92-9C13H15N3O3S
tert-Butyl N-[3-(4-hydroxyphenyl)-1,2,4-thiadiazol-5-yl]carbamate chemical structure, C13H15N3O3S, CAS 2413867-87-3
tert-Butyl N-[3-(4-hydroxyphenyl)-1,2,4-thiadiazol-5-yl]carbamate
CAS 2413867-87-3C13H15N3O3S
3-(4-Ethylphenyl)-1,2,4-thiadiazole-5-carboxylic acid chemical structure, C11H10N2O2S, CAS 2138518-34-8
3-(4-Ethylphenyl)-1,2,4-thiadiazole-5-carboxylic acid
CAS 2138518-34-8C11H10N2O2S
tert-Butyl N-[3-(4-bromophenyl)-1,2,4-thiadiazol-5-yl]carbamate chemical structure, C13H14BrN3O2S, CAS 2680683-73-0
tert-Butyl N-[3-(4-bromophenyl)-1,2,4-thiadiazol-5-yl]carbamate
CAS 2680683-73-0C13H14BrN3O2S
3-(5-Amino-1,2,4-thiadiazol-3-yl)phenol hydrochloride chemical structure, C8H8ClN3OS, CAS 2680534-18-1
3-(5-Amino-1,2,4-thiadiazol-3-yl)phenol hydrochloride
CAS 2680534-18-1C8H8ClN3OS
1-(3-Phenyl-1,2,4-thiadiazol-5-yl)methanamine hydrochloride chemical structure, C9H10ClN3S, CAS 1226866-75-6
1-(3-Phenyl-1,2,4-thiadiazol-5-yl)methanamine hydrochloride
CAS 1226866-75-6C9H10ClN3S
3-(2-Bromophenyl)-1,2,4-thiadiazole-5-carbohydrazide chemical structure, C9H7BrN4OS, CAS 2138118-63-3
3-(2-Bromophenyl)-1,2,4-thiadiazole-5-carbohydrazide
CAS 2138118-63-3C9H7BrN4OS
3-(3-Fluorophenyl)-1,2,4-thiadiazole-5-carbohydrazide chemical structure, C9H7FN4OS, CAS 2138585-72-3
3-(3-Fluorophenyl)-1,2,4-thiadiazole-5-carbohydrazide
CAS 2138585-72-3C9H7FN4OS
2-Chloro-N-[3-(3-chlorophenyl)-1,2,4-thiadiazol-5-yl]acetamide chemical structure, C10H7Cl2N3OS, CAS 2770494-28-3
2-Chloro-N-[3-(3-chlorophenyl)-1,2,4-thiadiazol-5-yl]acetamide
CAS 2770494-28-3C10H7Cl2N3OS
Sodium 2-(3-phenyl-1,2,4-thiadiazol-5-yl)acetate chemical structure, C10H7N2NaO2S, CAS 2866319-38-0
Sodium 2-(3-phenyl-1,2,4-thiadiazol-5-yl)acetate
CAS 2866319-38-0C10H7N2NaO2S
4-(5-(Methylsulfonyl)-1,2,4-thiadiazol-3-yl)benzoic acid chemical structure, C10H8N2O4S2, CAS 3040077-89-9
4-(5-(Methylsulfonyl)-1,2,4-thiadiazol-3-yl)benzoic acid
CAS 3040077-89-9C10H8N2O4S2
5-[(2-Methylprop-2-en-1-yl)sulfanyl]-3-phenyl-1,2,4-thiadiazole chemical structure, C12H12N2S2, CAS 3030778-66-3
5-[(2-Methylprop-2-en-1-yl)sulfanyl]-3-phenyl-1,2,4-thiadiazole
CAS 3030778-66-3C12H12N2S2
5-Propylsulfanyl-3-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazole chemical structure, C12H11F3N2S2, CAS 3054534-07-2
5-Propylsulfanyl-3-[3-(trifluoromethyl)phenyl]-1,2,4-thiadiazole
CAS 3054534-07-2C12H11F3N2S2
[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]methanol chemical structure, C9H7BrN2OS, CAS 2995277-34-2
[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]methanol
CAS 2995277-34-2C9H7BrN2OS
3-(4-Bromophenyl)-5-(chloromethyl)-1,2,4-thiadiazole chemical structure, C9H6BrClN2S, CAS 2995290-08-7
3-(4-Bromophenyl)-5-(chloromethyl)-1,2,4-thiadiazole
CAS 2995290-08-7C9H6BrClN2S
1-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]methanamine hydrochloride chemical structure, C9H9BrClN3S, CAS 3017264-92-2
1-[3-(4-Bromophenyl)-1,2,4-thiadiazol-5-yl]methanamine hydrochloride
CAS 3017264-92-2C9H9BrClN3S
Potassium 3-(4-bromophenyl)-1,2,4-thiadiazole-5-carboxylate chemical structure, C9H4BrKN2O2S, CAS 2995274-73-0
Potassium 3-(4-bromophenyl)-1,2,4-thiadiazole-5-carboxylate
CAS 2995274-73-0C9H4BrKN2O2S