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Murcko scaffold

2-(Pyrrolidin-1-yl)pyrimidine scaffold

431 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
431
With full pages
17
Scaffold SMILES

c1cnc(N2CCCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(Pyrrolidin-1-yl)pyrimidine page
Murcko scaffold c1cnc(N2CCCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 431 chemicals

2-(Pyrrolidinyl)pyrimidin-4-amine chemical structure, C8H12N4, CAS 33851-99-9
2-(Pyrrolidinyl)pyrimidin-4-amine
CAS 33851-99-9C8H12N4
1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid chemical structure, C9H11N3O2, CAS 1009282-26-1
1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid
CAS 1009282-26-1C9H11N3O2
4,6-Dimethyl-2-pyrrolidin-1-ylpyrimidine chemical structure, C10H15N3, CAS 24306-25-0
4,6-Dimethyl-2-pyrrolidin-1-ylpyrimidine
CAS 24306-25-0C10H15N3
(S)-1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid chemical structure, C9H11N3O2, CAS 1165543-55-4
(S)-1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid
CAS 1165543-55-4C9H11N3O2
(R)-1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid chemical structure, C9H11N3O2, CAS 1821832-73-8
(R)-1-(Pyrimidin-2-yl)pyrrolidine-2-carboxylic acid
CAS 1821832-73-8C9H11N3O2
5-Chloro-2-(pyrrolidin-1-yl)pyrimidine-4-carboxylic acid chemical structure, C9H10ClN3O2, CAS 327064-06-2
5-Chloro-2-(pyrrolidin-1-yl)pyrimidine-4-carboxylic acid
CAS 327064-06-2C9H10ClN3O2
5-(tert-Butylsulfonyl)-2-tetrahydro-1H-pyrrol-1-ylpyrimidin-4-amine chemical structure, C12H20N4O2S, CAS 175202-10-5
5-(tert-Butylsulfonyl)-2-tetrahydro-1H-pyrrol-1-ylpyrimidin-4-amine
CAS 175202-10-5C12H20N4O2S
4-Amino-2-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile chemical structure, C9H11N5, CAS 55441-53-7
4-Amino-2-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile
CAS 55441-53-7C9H11N5
5-(Isopropylsulfonyl)-2-(pyrrolidin-1-yl)pyrimidin-4-amine chemical structure, C11H18N4O2S, CAS 175202-04-7
5-(Isopropylsulfonyl)-2-(pyrrolidin-1-yl)pyrimidin-4-amine
CAS 175202-04-7C11H18N4O2S
1-(4,6-Dimethylpyrimidin-2-yl)pyrrolidine-2-carboxylic acid chemical structure, C11H15N3O2, CAS 956614-59-8
1-(4,6-Dimethylpyrimidin-2-yl)pyrrolidine-2-carboxylic acid
CAS 956614-59-8C11H15N3O2
2-((6-Amino-5-nitro-2-(pyrrolidin-1-yl)pyrimidin-4-yl)amino)ethanol chemical structure, C10H16N6O3, CAS 674329-06-7
2-((6-Amino-5-nitro-2-(pyrrolidin-1-yl)pyrimidin-4-yl)amino)ethanol
CAS 674329-06-7C10H16N6O3
5-Fluoro-N-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine chemical structure, C9H13FN4, CAS 880063-38-7
5-Fluoro-N-methyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine
CAS 880063-38-7C9H13FN4
5-Bromo-2-(pyrrolidin-1-yl)pyrimidine chemical structure, C8H10BrN3, CAS 446286-61-9
5-Bromo-2-(pyrrolidin-1-yl)pyrimidine
CAS 446286-61-9C8H10BrN3
2-Pyrrolidin-1-ylpyrimidine-5-carboxylic acid chemical structure, C9H11N3O2, CAS 253315-06-9
2-Pyrrolidin-1-ylpyrimidine-5-carboxylic acid
CAS 253315-06-9C9H11N3O2
1-(4,6-Dimethyl-2-pyrimidinyl)-D-proline chemical structure, C11H15N3O2, CAS 1217817-21-4
1-(4,6-Dimethyl-2-pyrimidinyl)-D-proline
CAS 1217817-21-4C11H15N3O2
4-Chloro-2-(pyrrolidin-1-yl)pyrimidine chemical structure, C8H10ClN3, CAS 33852-01-6
4-Chloro-2-(pyrrolidin-1-yl)pyrimidine
CAS 33852-01-6C8H10ClN3
2-(Pyrrolidin-1-yl)pyrimidine chemical structure, C8H11N3, CAS 192197-34-5
2-(Pyrrolidin-1-yl)pyrimidine
CAS 192197-34-5C8H11N3
1-(4-Methyl-2-pyrrolidin-1-ylpyrimidin-5-yl)ethanone chemical structure, C11H15N3O, CAS 66373-32-8
1-(4-Methyl-2-pyrrolidin-1-ylpyrimidin-5-yl)ethanone
CAS 66373-32-8C11H15N3O
N-Ethyl-2-(1-pyrrolidinyl)-4-pyrimidinamine chemical structure, C10H16N4, CAS 80957-69-3
N-Ethyl-2-(1-pyrrolidinyl)-4-pyrimidinamine
CAS 80957-69-3C10H16N4
4-Methyl-2-(1-pyrrolidinyl)-5-pyrimidinol chemical structure, C9H13N3O, CAS 92635-41-1
4-Methyl-2-(1-pyrrolidinyl)-5-pyrimidinol
CAS 92635-41-1C9H13N3O
Ethyl4-chloro-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylate chemical structure, C11H14ClN3O2, CAS 34750-25-9
Ethyl4-chloro-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylate
CAS 34750-25-9C11H14ClN3O2
6-Methyl-5-octyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine chemical structure, C17H30N4, CAS 113081-65-5
6-Methyl-5-octyl-2-(pyrrolidin-1-yl)pyrimidin-4-amine
CAS 113081-65-5C17H30N4
Methyl 4-methyl-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylate chemical structure, C11H15N3O2, CAS 924862-97-5
Methyl 4-methyl-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylate
CAS 924862-97-5C11H15N3O2
Ethyl 4-methyl-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylate chemical structure, C12H17N3O2, CAS 637003-39-5
Ethyl 4-methyl-2-(pyrrolidin-1-yl)pyrimidine-5-carboxylate
CAS 637003-39-5C12H17N3O2