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Murcko scaffold

Ring system with 3 rings and 19 atoms

277 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
277
With full pages
16
Scaffold SMILES

O=C(Cn1ccc2ccccc21)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cn1ccc2ccccc21)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 277 chemicals

2-{3-[(Carbamothioylamino)imino]-2-oxo-2,3-dihydro-1H-indol-1-yl}-N-phenylacetamide chemical structure, C17H15N5O2S, CAS 302968-28-1
2-{3-[(Carbamothioylamino)imino]-2-oxo-2,3-dihydro-1H-indol-1-yl}-N-phenylacetamide
CAS 302968-28-1C17H15N5O2S
2-(5-Bromo-3-formyl-1H-indol-1-yl)-N-(3-chloro-2-methylphenyl)acetamide chemical structure, C18H14BrClN2O2, CAS 499111-50-1
2-(5-Bromo-3-formyl-1H-indol-1-yl)-N-(3-chloro-2-methylphenyl)acetamide
CAS 499111-50-1C18H14BrClN2O2
2-(5-Bromo-3-formyl-1H-indol-1-yl)-N-(3,5-dimethylphenyl)acetamide chemical structure, C19H17BrN2O2, CAS 499111-60-3
2-(5-Bromo-3-formyl-1H-indol-1-yl)-N-(3,5-dimethylphenyl)acetamide
CAS 499111-60-3C19H17BrN2O2
2-(3-Acetyl-1H-indol-1-yl)-N-(2,5-dimethoxyphenyl)acetamide chemical structure, C20H20N2O4, CAS 717836-90-3
2-(3-Acetyl-1H-indol-1-yl)-N-(2,5-dimethoxyphenyl)acetamide
CAS 717836-90-3C20H20N2O4
Methyl 4-{[(5-bromo-3-formyl-1H-indol-1-yl)acetyl]amino}benzoate chemical structure, C19H15BrN2O4, CAS 593235-61-1
Methyl 4-{[(5-bromo-3-formyl-1H-indol-1-yl)acetyl]amino}benzoate
CAS 593235-61-1C19H15BrN2O4
Methyl 2-{[(3-formyl-2-methyl-1H-indol-1-yl)acetyl]amino}benzoate chemical structure, C20H18N2O4, CAS 592550-48-6
Methyl 2-{[(3-formyl-2-methyl-1H-indol-1-yl)acetyl]amino}benzoate
CAS 592550-48-6C20H18N2O4
N-(4-Bromophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide chemical structure, C17H13BrN2O2, CAS 384352-97-0
N-(4-Bromophenyl)-2-(3-formyl-1H-indol-1-yl)acetamide
CAS 384352-97-0C17H13BrN2O2
2-[3-(Hydroxymethyl)-1H-indol-1-yl]-N-phenylacetamide chemical structure, C17H16N2O2, CAS 680585-14-2
2-[3-(Hydroxymethyl)-1H-indol-1-yl]-N-phenylacetamide
CAS 680585-14-2C17H16N2O2
2-(3-Formylindol-1-yl)-N-(4-nitrophenyl)acetamide chemical structure, C17H13N3O4, CAS 592546-61-7
2-(3-Formylindol-1-yl)-N-(4-nitrophenyl)acetamide
CAS 592546-61-7C17H13N3O4
N-(5-Chloro-2-methoxyphenyl)-2-(1H-indol-1-yl)acetamide chemical structure, C17H15ClN2O2, CAS 768380-23-0
N-(5-Chloro-2-methoxyphenyl)-2-(1H-indol-1-yl)acetamide
CAS 768380-23-0C17H15ClN2O2
2-(3-Acetylindol-1-yl)-N-(2-methoxyphenyl)acetamide chemical structure, C19H18N2O3, CAS 830349-93-4
2-(3-Acetylindol-1-yl)-N-(2-methoxyphenyl)acetamide
CAS 830349-93-4C19H18N2O3
N-(3-Methylphenyl)-2-[3-(2,2,2-trifluoroacetyl)indol-1-yl]acetamide chemical structure, C19H15F3N2O2, CAS 5178-21-2
N-(3-Methylphenyl)-2-[3-(2,2,2-trifluoroacetyl)indol-1-yl]acetamide
CAS 5178-21-2C19H15F3N2O2
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(2-methoxy-5-methylphenyl)- chemical structure, C21H22N2O3, CAS 593236-77-2
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(2-methoxy-5-methylphenyl)-
CAS 593236-77-2C21H22N2O3
Methyl 4-{[(5-bromo-1H-indol-1-yl)acetyl]amino}benzoate chemical structure, C18H15BrN2O3, CAS 870139-60-9
Methyl 4-{[(5-bromo-1H-indol-1-yl)acetyl]amino}benzoate
CAS 870139-60-9C18H15BrN2O3
2-(7-Ethyl-3-formylindol-1-yl)-N-(4-methoxyphenyl)acetamide chemical structure, C20H20N2O3, CAS 593236-70-5
2-(7-Ethyl-3-formylindol-1-yl)-N-(4-methoxyphenyl)acetamide
CAS 593236-70-5C20H20N2O3
1H-Indole-1-acetamide, 7-ethyl-N-(3-fluoro-2-methylphenyl)-3-formyl- chemical structure, C20H19FN2O2, CAS 593236-37-4
1H-Indole-1-acetamide, 7-ethyl-N-(3-fluoro-2-methylphenyl)-3-formyl-
CAS 593236-37-4C20H19FN2O2
1H-Indole-1-acetamide, 7-ethyl-N-(2-ethylphenyl)-3-formyl- chemical structure, C21H22N2O2, CAS 593236-76-1
1H-Indole-1-acetamide, 7-ethyl-N-(2-ethylphenyl)-3-formyl-
CAS 593236-76-1C21H22N2O2
Ethyl 4-[[2-(3-formylindol-1-yl)acetyl]amino]benzoate chemical structure, C20H18N2O4, CAS 496960-32-8
Ethyl 4-[[2-(3-formylindol-1-yl)acetyl]amino]benzoate
CAS 496960-32-8C20H18N2O4
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(4-nitrophenyl)- chemical structure, C19H17N3O4, CAS 593236-78-3
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(4-nitrophenyl)-
CAS 593236-78-3C19H17N3O4
Methyl 2-[[2-(7-ethyl-3-formylindol-1-yl)acetyl]amino]benzoate chemical structure, C21H20N2O4, CAS 593237-21-9
Methyl 2-[[2-(7-ethyl-3-formylindol-1-yl)acetyl]amino]benzoate
CAS 593237-21-9C21H20N2O4
2-(7-Ethyl-3-formylindol-1-yl)-N-(3-nitrophenyl)acetamide chemical structure, C19H17N3O4, CAS 593236-87-4
2-(7-Ethyl-3-formylindol-1-yl)-N-(3-nitrophenyl)acetamide
CAS 593236-87-4C19H17N3O4
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(2-nitrophenyl)- chemical structure, C19H17N3O4, CAS 593236-80-7
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(2-nitrophenyl)-
CAS 593236-80-7C19H17N3O4
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(2-methyl-5-nitrophenyl)- chemical structure, C20H19N3O4, CAS 593236-68-1
1H-Indole-1-acetamide, 7-ethyl-3-formyl-N-(2-methyl-5-nitrophenyl)-
CAS 593236-68-1C20H19N3O4
1H-Indole-1-acetamide, 7-ethyl-N-(5-fluoro-2-methylphenyl)-3-formyl- chemical structure, C20H19FN2O2, CAS 593236-39-6
1H-Indole-1-acetamide, 7-ethyl-N-(5-fluoro-2-methylphenyl)-3-formyl-
CAS 593236-39-6C20H19FN2O2