Murcko scaffold
3-Phenylpyrrolidine scaffold
4,373 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 4,373
- With full pages
- 8
Scaffold SMILES
c1ccc(C2CCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,585 to 1,632 of 4,373 chemicals
![3-Fluoro-3-[3-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C11H11F4N, CAS 1564461-37-5](/s/RCVAYEMTTGYFMP-UHFFFAOYSA-N.svg)
3-Fluoro-3-[3-(trifluoromethyl)phenyl]pyrrolidine
CAS 1564461-37-5C11H11F4N
(1-Boc-3-phenyl-3-pyrrolidinyl)methanamine
CAS 1782782-30-2C16H24N2O2
4-(1-Methyl-3-pyrrolidinyl)benzaldehyde
CAS 1547119-74-3C12H15NO
4-(3-Methylpyrrolidin-3-yl)phenol
CAS 1557730-41-2C11H15NO
3-(3-Methylpyrrolidin-3-yl)phenol
CAS 1551031-54-9C11H15NO
2-(3-Methylpyrrolidin-3-yl)phenol
CAS 1554483-08-7C11H15NO
![N-[3-(Pyrrolidin-3-yl)phenyl]acetamide chemical structure, C12H16N2O, CAS 1260741-19-2](/s/DSINYGGCOHYQJC-UHFFFAOYSA-N.svg)
N-[3-(Pyrrolidin-3-yl)phenyl]acetamide
CAS 1260741-19-2C12H16N2O
![tert-Butyl N-[4-(pyrrolidin-3-yl)phenyl]carbamate chemical structure, C15H22N2O2, CAS 1260768-56-6](/s/VASPNWBCYYXHFK-UHFFFAOYSA-N.svg)
tert-Butyl N-[4-(pyrrolidin-3-yl)phenyl]carbamate
CAS 1260768-56-6C15H22N2O2
![tert-Butyl N-[3-(pyrrolidin-3-yl)phenyl]carbamate chemical structure, C15H22N2O2, CAS 1260795-93-4](/s/OWJXVLBLQLIQRM-UHFFFAOYSA-N.svg)
tert-Butyl N-[3-(pyrrolidin-3-yl)phenyl]carbamate
CAS 1260795-93-4C15H22N2O2
![tert-Butyl N-[2-(pyrrolidin-3-yl)phenyl]carbamate chemical structure, C15H22N2O2, CAS 1781580-09-3](/s/QFMAVFPMRJYTRU-UHFFFAOYSA-N.svg)
tert-Butyl N-[2-(pyrrolidin-3-yl)phenyl]carbamate
CAS 1781580-09-3C15H22N2O2
3-(2,5-Difluoro-4-methylphenyl)pyrrolidine
CAS 1556558-02-1C11H13F2N
3-(3,4-Difluoro-2-methoxyphenyl)pyrrolidine
CAS 1336969-92-6C11H13F2NO
3-(2,6-Difluoro-4-methoxyphenyl)pyrrolidine
CAS 1337351-26-4C11H13F2NO
3-(3,5-Difluoro-2-methoxyphenyl)pyrrolidine
CAS 1260830-33-8C11H13F2NO
3-(2-Chloro-4,5-difluorophenyl)pyrrolidine
CAS 1260757-49-0C10H10ClF2N
3-(2,5-Dichloro-3-fluorophenyl)pyrrolidine
CAS 1260649-68-0C10H10Cl2FN
3-(4-Bromo-2,6-difluorophenyl)pyrrolidine
CAS 1260781-99-4C10H10BrF2N
4-Bromo-2-methoxy-5-(pyrrolidin-3-yl)phenol
CAS 1260753-81-8C11H14BrNO2
5-Bromo-2-methoxy-4-(pyrrolidin-3-yl)phenol
CAS 1260845-88-2C11H14BrNO2
3-(2-Methoxy-6-methylphenyl)pyrrolidine
CAS 1336967-44-2C12H17NO
![3-[2-(Methylsulfanyl)phenyl]pyrrolidine chemical structure, C11H15NS, CAS 1260794-60-2](/s/BRFUOYSBCZPKGA-UHFFFAOYSA-N.svg)
3-[2-(Methylsulfanyl)phenyl]pyrrolidine
CAS 1260794-60-2C11H15NS
3-(2,6-Difluoro-3-methylphenyl)pyrrolidine
CAS 1260771-28-5C11H13F2N
3-(3,5-Dimethoxy-4-methylphenyl)pyrrolidine
CAS 1897750-48-9C13H19NO2
3-(3-Fluoro-2,6-dimethoxyphenyl)pyrrolidine
CAS 1781667-99-9C12H16FNO2
- 3-[2-Fluoro-4-(trifluoromethyl)phenyl]pyrrolidine1260847-15-1C11H11F4N
- tert-Butyl 3-hydroxy-3-(4-methoxyphenyl)pyrrolidine-1-carboxylate1635405-03-6C16H23NO4
- tert-Butyl 3-hydroxy-3-(3-methoxyphenyl)pyrrolidine-1-carboxylate1784202-19-2C16H23NO4
- tert-Butyl 3-(3-fluorophenyl)-3-hydroxypyrrolidine-1-carboxylate1781663-64-6C15H20FNO3
- 4-(1-Methylpyrrolidin-3-yl)aniline1378584-62-3C11H16N2
- 3,3-Dimethyl-4-(o-tolyl)pyrrolidine1781518-36-2C13H19N
- 3,3-Dimethyl-4-(m-tolyl)pyrrolidine1783464-14-1C13H19N
- 3,3-Dimethyl-4-(4-methylphenyl)pyrrolidine1784325-91-2C13H19N
- 4-(2-Fluorophenyl)-3,3-dimethylpyrrolidine1780156-74-2C12H16FN
- 4-(4-Fluorophenyl)-3,3-dimethylpyrrolidine1779985-88-4C12H16FN
- 4-(3-Fluorophenyl)-3,3-dimethylpyrrolidine1782711-41-4C12H16FN
- 4-(4-Ethylphenyl)-3,3-dimethylpyrrolidine1784670-68-3C14H21N
- 4-(2-Methoxyphenyl)-3,3-dimethylpyrrolidine1781903-04-5C13H19NO
- 4-(3-Methoxyphenyl)-3,3-dimethylpyrrolidine1779800-38-2C13H19NO
- 4-(4-Methoxyphenyl)-3,3-dimethylpyrrolidine1783563-56-3C13H19NO
- 4-(2-Chlorophenyl)-3,3-dimethylpyrrolidine1784800-45-8C12H16ClN
- 4-(3-Chlorophenyl)-3,3-dimethylpyrrolidine1784804-73-4C12H16ClN
- 4-(4-Chlorophenyl)-3,3-dimethylpyrrolidine1784800-49-2C12H16ClN
- 4-(4-Isopropylphenyl)-3,3-dimethylpyrrolidine1783443-97-9C15H23N
- 4-(3-Ethoxyphenyl)-3,3-dimethylpyrrolidine1784473-48-8C14H21NO
- 4-(4-Ethoxyphenyl)-3,3-dimethylpyrrolidine1783528-46-0C14H21NO
- 4-[1-(2-Methoxyethyl)-3-pyrrolidinyl]benzenamine1781817-58-0C13H20N2O
- 4-(1-Acetylpyrrolidin-3-yl)benzoic acid1784670-56-9C13H15NO3
- 3-(1-Acetylpyrrolidin-3-yl)benzoic acid1785014-19-8C13H15NO3
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