Murcko scaffold
3-Phenylpyrrolidine scaffold
4,373 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 4,373
- With full pages
- 8
Scaffold SMILES
c1ccc(C2CCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,633 to 1,680 of 4,373 chemicals
4-(3,4-Dimethoxyphenyl)-3,3-dimethylpyrrolidine
CAS 1785193-37-4C14H21NO2
4-(2,5-Dimethoxyphenyl)-3,3-dimethylpyrrolidine
CAS 1780080-19-4C14H21NO2
4-(3,5-Dimethoxyphenyl)-3,3-dimethylpyrrolidine
CAS 1782503-83-6C14H21NO2
3-(3-Bromo-phenyl)-1-methyl-pyrrolidine
CAS 1379306-38-3C11H14BrN
3-(3-Bromophenyl)pyrrolidin-3-ol
CAS 1260785-78-1C10H12BrNO
4-(4-Bromophenyl)-3,3-dimethylpyrrolidine
CAS 1784676-60-3C12H16BrN
![1-[3-(4-Bromophenyl)pyrrolidin-1-yl]ethanone chemical structure, C12H14BrNO, CAS 1467060-22-5](/s/FCLZZIJJMSFCOG-UHFFFAOYSA-N.svg)
1-[3-(4-Bromophenyl)pyrrolidin-1-yl]ethanone
CAS 1467060-22-5C12H14BrNO
3-(4-Bromophenyl)-1-(1-methylethyl)pyrrolidine
CAS 1780251-45-7C13H18BrN
Methyl 3-(4-bromophenyl)pyrrolidine-1-carboxylate
CAS 1467060-19-0C12H14BrNO2
3-(4-Bromophenyl)-1-(methylsulfonyl)pyrrolidine
CAS 1467060-25-8C11H14BrNO2S
tert-Butyl 3-(3-bromophenyl)pyrrolidine-1-carboxylate
CAS 1203685-37-3C15H20BrNO2
3-(3-Ethylphenyl)pyrrolidine
CAS 1260822-02-3C12H17N
3-(2-(Difluoromethyl)phenyl)pyrrolidine
CAS 1260864-77-4C11H13F2N
4,5-Difluoro-2-(pyrrolidin-3-yl)phenol
CAS 1260860-79-4C10H11F2NO
3-(2,4,5-Trifluorophenyl)pyrrolidine
CAS 1260814-64-9C10H10F3N
3-(5-Fluoro-2-methoxy-4-methylphenyl)pyrrolidine
CAS 1780750-12-0C12H16FNO
3-(2-Chloro-6-methoxyphenyl)pyrrolidine
CAS 1337309-14-4C11H14ClNO
3-(4,5-Difluoro-2-methoxyphenyl)pyrrolidine
CAS 1260823-21-9C11H13F2NO
3-(3-Chloro-2,6-difluorophenyl)pyrrolidine
CAS 1260753-27-2C10H10ClF2N
![3-[2-Fluoro-3-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C11H11F4N, CAS 1260770-79-3](/s/VHRIURFYUCUNEO-UHFFFAOYSA-N.svg)
3-[2-Fluoro-3-(trifluoromethyl)phenyl]pyrrolidine
CAS 1260770-79-3C11H11F4N
3-(2-Bromo-6-fluorophenyl)pyrrolidine
CAS 1260822-32-9C10H11BrFN
![3-[2-Methoxy-5-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C12H14F3NO, CAS 1260679-97-7](/s/PGZDDYCYHMVUPK-UHFFFAOYSA-N.svg)
3-[2-Methoxy-5-(trifluoromethyl)phenyl]pyrrolidine
CAS 1260679-97-7C12H14F3NO
![3-[4-Methoxy-3-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C12H14F3NO, CAS 1260794-90-8](/s/TZZACZRFTDHTGY-UHFFFAOYSA-N.svg)
3-[4-Methoxy-3-(trifluoromethyl)phenyl]pyrrolidine
CAS 1260794-90-8C12H14F3NO
![3-[2-Methoxy-3-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C12H14F3NO, CAS 1784300-36-2](/s/CGTUVWOAXVGLFA-UHFFFAOYSA-N.svg)
3-[2-Methoxy-3-(trifluoromethyl)phenyl]pyrrolidine
CAS 1784300-36-2C12H14F3NO
- 3-[4-Methoxy-2-(trifluoromethyl)phenyl]pyrrolidine1784959-27-8C12H14F3NO
- 3-[2-Chloro-6-(trifluoromethyl)phenyl]pyrrolidine1785423-28-0C11H11ClF3N
- 3-(2-Bromo-6-methoxyphenyl)pyrrolidine1337362-78-3C11H14BrNO
- 3-(2-Bromo-6-chlorophenyl)pyrrolidine1337444-15-1C10H11BrClN
- tert-Butyl 3-(2-hydroxyphenyl)pyrrolidine-1-carboxylate1784582-80-4C15H21NO3
- tert-Butyl 3-(4-hydroxyphenyl)pyrrolidine-1-carboxylate1782362-27-9C15H21NO3
- 3-(2-Fluoro-6-methylphenyl)pyrrolidine1337297-12-7C11H14FN
- 2-Fluoro-5-(pyrrolidin-3-yl)benzonitrile1260871-33-7C11H11FN2
- 2,6-Dimethyl-4-(pyrrolidin-3-yl)aniline1260683-16-6C12H18N2
- 2,4-Difluoro-6-(pyrrolidin-3-yl)phenol1260857-59-7C10H11F2NO
- 3-(2-tert-Butylphenyl)pyrrolidine1260648-99-4C14H21N
- 3-(3,4-Difluoro-5-methoxyphenyl)pyrrolidine1260814-01-4C11H13F2NO
- 3-(2,4-Difluoro-6-methoxyphenyl)pyrrolidine1337206-59-3C11H13F2NO
- 3-(3-Chloro-2-fluoro-6-methylphenyl)pyrrolidine1260862-87-0C11H13ClFN
- 3-(4-Chloro-2,5-difluorophenyl)pyrrolidine1260781-66-5C10H10ClF2N
- 3-(3-Chloro-2,4-difluorophenyl)pyrrolidine1260682-16-3C10H10ClF2N
- 4-(3-Methoxyphenyl)-1-methylpyrrolidine-3-carboxylic acid1706442-15-0C13H17NO3
- 4-(3-Chlorophenyl)-1-methylpyrrolidine-3-carboxylic acid1706456-11-2C12H14ClNO2
- 3-(2-Bromo-phenyl)-1-methyl-pyrrolidine1379355-06-2C11H14BrN
- 3-[3-Methoxy-4-(trifluoromethyl)phenyl]pyrrolidine1391268-73-7C12H14F3NO
- 3-(3-Bromo-2,4-dimethylphenyl)pyrrolidine1784612-68-5C12H16BrN
- 3-(4-Bromo-3,5-dimethylphenyl)pyrrolidine1780304-24-6C12H16BrN
- 3-(3-Bromo-2,4-difluorophenyl)pyrrolidine1781141-90-9C10H10BrF2N
- 3-(4-Bromo-3,5-dimethoxyphenyl)pyrrolidine1260864-85-4C12H16BrNO2
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