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Murcko scaffold

3-Phenylpyrrolidine scaffold

4,373 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
4,373
With full pages
8
Scaffold SMILES

c1ccc(C2CCNC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrrolidine page
Murcko scaffold c1ccc(C2CCNC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1,681 to 1,728 of 4,373 chemicals

4-(4-Isopropylphenyl)pyrrolidin-3-amine chemical structure, C13H20N2, CAS 2098121-40-3
4-(4-Isopropylphenyl)pyrrolidin-3-amine
CAS 2098121-40-3C13H20N2
1-Methyl-3-nitro-4-phenylpyrrolidine chemical structure, C11H14N2O2, CAS 122079-48-5
1-Methyl-3-nitro-4-phenylpyrrolidine
CAS 122079-48-5C11H14N2O2
4-(4-Chlorophenyl)pyrrolidin-2-ol chemical structure, C10H12ClNO, CAS 120418-63-5
4-(4-Chlorophenyl)pyrrolidin-2-ol
CAS 120418-63-5C10H12ClNO
3-(4-Chlorophenyl)-3-pyrrolidinemethanol chemical structure, C11H14ClNO, CAS 52423-66-2
3-(4-Chlorophenyl)-3-pyrrolidinemethanol
CAS 52423-66-2C11H14ClNO
3-(4-Chlorophenyl)proline hydrochloride chemical structure, C11H13Cl2NO2, CAS 851484-36-1
3-(4-Chlorophenyl)proline hydrochloride
CAS 851484-36-1C11H13Cl2NO2
Methyl (3R,4S)-4-(4-chlorophenyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C12H15Cl2NO2, CAS 1630945-13-9
Methyl (3R,4S)-4-(4-chlorophenyl)pyrrolidine-3-carboxylate hydrochloride
CAS 1630945-13-9C12H15Cl2NO2
(r)-4-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid chemical structure, C16H21NO4, CAS 2361922-71-4
(r)-4-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid
CAS 2361922-71-4C16H21NO4
(r)-3-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid chemical structure, C16H21NO4, CAS 2361923-54-6
(r)-3-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid
CAS 2361923-54-6C16H21NO4
(s)-4-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid chemical structure, C16H21NO4, CAS 2361922-29-2
(s)-4-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid
CAS 2361922-29-2C16H21NO4
(s)-3-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid chemical structure, C16H21NO4, CAS 2361918-29-6
(s)-3-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid
CAS 2361918-29-6C16H21NO4
4-Pyrrolidin-3-yl-phenol hydrochloride chemical structure, C10H14ClNO, CAS 1956356-22-1
4-Pyrrolidin-3-yl-phenol hydrochloride
CAS 1956356-22-1C10H14ClNO
rac-tert-Butyl (3R,4S)-3-(4-fluorophenyl)-4-hydroxypyrrolidine-1-carboxylate chemical structure, C15H20FNO3, CAS 849674-13-1
rac-tert-Butyl (3R,4S)-3-(4-fluorophenyl)-4-hydroxypyrrolidine-1-carboxylate
CAS 849674-13-1C15H20FNO3
tert-Butyl 3-(3-chloro-2-fluorophenyl)-3-methoxypyrrolidin-1-carboxylate chemical structure, C16H21ClFNO3, CAS 1227688-65-4
tert-Butyl 3-(3-chloro-2-fluorophenyl)-3-methoxypyrrolidin-1-carboxylate
CAS 1227688-65-4C16H21ClFNO3
rac-1-tert-Butyl 3-methyl (3R,4S)-4-(3-bromophenyl)pyrrolidine-1,3-dicarboxylate chemical structure, C17H22BrNO4, CAS 1354721-10-0
rac-1-tert-Butyl 3-methyl (3R,4S)-4-(3-bromophenyl)pyrrolidine-1,3-dicarboxylate
CAS 1354721-10-0C17H22BrNO4
Methyl (3S,4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C12H14ClF2NO2, CAS 1244781-14-3
Methyl (3S,4R)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylate hydrochloride
CAS 1244781-14-3C12H14ClF2NO2
[1-Allyl-4-amino-4-(3-bromophenyl)pyrrolidin-3-yl]methanol chemical structure, C14H19BrN2O, CAS 1628690-43-6
[1-Allyl-4-amino-4-(3-bromophenyl)pyrrolidin-3-yl]methanol
CAS 1628690-43-6C14H19BrN2O
trans-4-Phenylpyrrolidin-3-ol hemioxalate chemical structure, C22H28N2O6, CAS 1706429-96-0
trans-4-Phenylpyrrolidin-3-ol hemioxalate
CAS 1706429-96-0C22H28N2O6
2-Methyl-4-(4-methylphenyl)pyrrolidine-2-carboxylic acid hydrochloride chemical structure, C13H18ClNO2, CAS 1798775-41-3
2-Methyl-4-(4-methylphenyl)pyrrolidine-2-carboxylic acid hydrochloride
CAS 1798775-41-3C13H18ClNO2
1-(2-Methoxyethyl)-4-phenyl-3-pyrrolidinamine chemical structure, C13H20N2O, CAS 1879233-51-8
1-(2-Methoxyethyl)-4-phenyl-3-pyrrolidinamine
CAS 1879233-51-8C13H20N2O
rel-(3S,4R)-1-(2-Methoxyethyl)-4-phenylpyrrolidin-3-amine dihydrochloride chemical structure, C13H22Cl2N2O, CAS 1414566-62-3
rel-(3S,4R)-1-(2-Methoxyethyl)-4-phenylpyrrolidin-3-amine dihydrochloride
CAS 1414566-62-3C13H22Cl2N2O
(3S,4R)-4-(3-Fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-amine dihydrochloride chemical structure, C13H21Cl2FN2O, CAS 1414567-41-1
(3S,4R)-4-(3-Fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-amine dihydrochloride
CAS 1414567-41-1C13H21Cl2FN2O
tert-Butyl 3-phenyl-4-(trifluoroacetamido)pyrrolidine-1-carboxylate chemical structure, C17H21F3N2O3, CAS 1803599-56-5
tert-Butyl 3-phenyl-4-(trifluoroacetamido)pyrrolidine-1-carboxylate
CAS 1803599-56-5C17H21F3N2O3
rel-(3S,4R)-1-Methyl-4-phenylpyrrolidin-3-amine chemical structure, C11H16N2, CAS 1589806-78-9
rel-(3S,4R)-1-Methyl-4-phenylpyrrolidin-3-amine
CAS 1589806-78-9C11H16N2
(3R)-3-(3,5-Dichlorophenyl)-1-methyl-3-(trifluoromethyl)pyrrolidine chemical structure, C12H12Cl2F3N, CAS 1429624-38-3
(3R)-3-(3,5-Dichlorophenyl)-1-methyl-3-(trifluoromethyl)pyrrolidine
CAS 1429624-38-3C12H12Cl2F3N