Murcko scaffold
3-Phenylpyrrolidine scaffold
4,373 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 11
- Chemicals
- 4,373
- With full pages
- 8
Scaffold SMILES
c1ccc(C2CCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,729 to 1,776 of 4,373 chemicals
3-(2-Bromophenyl)pyrrolidine hydrochloride
CAS 1203682-28-3C10H13BrClN
![3-Fluoro-3-[3-(trifluoromethoxy)phenyl]pyrrolidine hydrochloride chemical structure, C11H12ClF4NO, CAS 1803593-44-3](/s/IPABLFIXZLQOJS-UHFFFAOYSA-N.svg)
3-Fluoro-3-[3-(trifluoromethoxy)phenyl]pyrrolidine hydrochloride
CAS 1803593-44-3C11H12ClF4NO
![3-Fluoro-3-[3-(trifluoromethoxy)phenyl]pyrrolidine chemical structure, C11H11F4NO, CAS 1713334-02-1](/s/FCIKGJCKPHSFMF-UHFFFAOYSA-N.svg)
3-Fluoro-3-[3-(trifluoromethoxy)phenyl]pyrrolidine
CAS 1713334-02-1C11H11F4NO
![3-Fluoro-3-[4-(trifluoromethyl)phenyl]pyrrolidine hydrochloride chemical structure, C11H12ClF4N, CAS 1803602-12-1](/s/NRDHTUPRMRJFSP-UHFFFAOYSA-N.svg)
3-Fluoro-3-[4-(trifluoromethyl)phenyl]pyrrolidine hydrochloride
CAS 1803602-12-1C11H12ClF4N
![3-Fluoro-3-[4-(trifluoromethyl)phenyl]pyrrolidine chemical structure, C11H11F4N, CAS 1565454-25-2](/s/YGMYKGYDSIXSJJ-UHFFFAOYSA-N.svg)
3-Fluoro-3-[4-(trifluoromethyl)phenyl]pyrrolidine
CAS 1565454-25-2C11H11F4N
3-Fluoro-3-(4-fluorophenyl)pyrrolidine hydrochloride
CAS 1803589-76-5C10H12ClF2N
3-Fluoro-3-(2-fluorophenyl)pyrrolidine hydrochloride
CAS 1803561-18-3C10H12ClF2N
trans-Ethyl 1-methyl-4-phenylpyrrolidine-3-carboxylate
CAS 652972-72-0C14H19NO2
(3S,4R)-1-(2,2-Difluoroethyl)-4-phenylpyrrolidin-3-amine
CAS 1972618-10-2C12H16F2N2
(R)-3-(3,4-Difluorophenyl)pyrrolidine
CAS 1335886-75-3C10H11F2N
(r)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid
CAS 2361926-06-7C16H21NO4
(s)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)benzoic acid
CAS 2361923-36-4C16H21NO4
Methyl 3-(pyrrolidin-3-yl)benzoate hydrochloride
CAS 1166820-45-6C12H16ClNO2
Methyl 2-(pyrrolidin-3-yl)benzoate hydrochloride
CAS 1166820-44-5C12H16ClNO2
tert-Butyl 3-(hydroxymethyl)-4-(3-methoxyphenyl)pyrrolidine-1-carboxylate
CAS 1823978-63-7C17H25NO4
tert-Butyl 3-(hydroxymethyl)-4-(p-tolyl)pyrrolidine-1-carboxylate
CAS 1367102-93-9C17H25NO3
Sodium 2-(1-(tert-butoxycarbonyl)-3-phenylpyrrolidin-3-yl)acetate
CAS 1956308-02-3C17H22NNaO4
rel-tert-Butyl (3R,4S)-3-amino-4-(3-(trifluoromethyl)phenyl)pyrrolidine-1-carboxylate
CAS 1357073-25-6C16H21F3N2O2
rel-tert-Butyl (3R,4S)-3-amino-4-(4-(trifluoromethyl)phenyl)pyrrolidine-1-carboxylate
CAS 1357073-27-8C16H21F3N2O2
rel-tert-Butyl (3R,4S)-3-amino-4-(3-fluorophenyl)pyrrolidine-1-carboxylate
CAS 1357072-90-2C15H21FN2O2
(S)-3-(3,4-Difluorophenyl)pyrrolidine
CAS 1335947-25-5C10H11F2N
(3R,4R)-4-Phenylpyrrolidin-3-ol
CAS 1932274-33-3C10H13NO
(3S,4S)-4-Phenylpyrrolidin-3-ol
CAS 2165944-46-5C10H13NO
(3S,4S)-4-(2-Cyanophenyl)pyrrolidine-3-carboxylic acid
C12H12N2O2
- (3S,4S)-4-(2-Fluorophenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acidC16H20FNO4
- (3R,4R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-4-(4-nitrophenyl)pyrrolidine-3-carboxylic acidC16H20N2O6
- (3R,4R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-4-(3-nitrophenyl)pyrrolidine-3-carboxylic acidC16H20N2O6
- (3R,4R)-4-(3-Bromophenyl)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-3-carboxylic acidC16H20BrNO4
- trans-Methyl 4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylate765247-28-7C13H14F3NO2
- (S)-3-(3,4,5-Trifluorophenyl)pyrrolidine1336337-14-4C10H10F3N
- rac-Methyl (3R,4S)-4-(4-methylphenyl)pyrrolidine-3-carboxylate1381947-62-1C13H17NO2
- Methyl (3S,4S)-4-(p-tolyl)pyrrolidine-3-carboxylate2351151-10-3C13H17NO2
- rac-(3R,4R)-4-Phenylpyrrolidine-3-carboxylic acid1932037-44-9C11H13NO2
- (S)-3-(2-Bromophenyl)pyrrolidine1336285-72-3C10H12BrN
- (R)-3-(2-Bromophenyl)pyrrolidine1336778-64-3C10H12BrN
- rel-(3S,4R)-4-(2-Fluorophenyl)-1-methylpyrrolidin-3-amine1431721-04-8C11H15FN2
- rac-(3R,4S)-4-(3-Fluoro-4-methoxyphenyl)pyrrolidine-3-carboxylic acid2227753-85-5C12H14FNO3
- rac-(3R,4S)-4-(4-Methoxyphenyl)-1-methylpyrrolidine-3-carboxylic acid2227840-29-9C13H17NO3
- rac-(3R,4S)-4-(2-Methoxy-4-methylphenyl)pyrrolidine-3-carboxylic acid2227790-41-0C13H17NO3
- rac-(3R,4S)-4-[4-(Dimethylamino)phenyl]pyrrolidine-3-carboxylic acid2227842-00-2C13H18N2O2
- rac-[(3R,4R)-1-Methyl-4-phenylpyrrolidin-3-yl]methanamine2307782-86-9C12H18N2
- rel-(3S,4R)-4-(4-Fluorophenyl)-1-methylpyrrolidin-3-amine1431720-07-8C11H15FN2
- rac-(3R,4S)-4-(2-Methoxy-5-methylphenyl)pyrrolidine-3-carboxylic acid2227842-41-1C13H17NO3
- ((3R,4R)-4-(4-Chloro-2-fluorophenyl)pyrrolidin-3-yl)methanol2165827-72-3C11H13ClFNO
- Ethyl (3S,4S)-1-methyl-4-phenylpyrrolidine-3-carboxylateC14H19NO2
- rac-tert-Butyl (2R,3S)-3-phenylpyrrolidine-2-carboxylate153243-97-1C15H21NO2
- 3-Fluoro-3-phenylpyrrolidine hydrochloride1803603-31-7C10H13ClFN
- 1-Methyl-4-[4-(propan-2-yl)phenyl]pyrrolidin-3-amine1706441-81-7C14H22N2
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