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Murcko scaffold

3-Phenylpyrrolidine scaffold

4,373 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
4,373
With full pages
197
Scaffold SMILES

c1ccc(C2CCNC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrrolidine page
Murcko scaffold c1ccc(C2CCNC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 4,373 chemicals

(3S,4R)-4-(4-Methylphenyl)pyrrolidine-3-carboxylic acid hydrochloride chemical structure, C12H16ClNO2, CAS 1049728-10-0
(3S,4R)-4-(4-Methylphenyl)pyrrolidine-3-carboxylic acid hydrochloride
CAS 1049728-10-0C12H16ClNO2
(3S,4R)-4-p-Tolylpyrrolidine-3-carboxylic acid chemical structure, C12H15NO2, CAS 1049976-10-4
(3S,4R)-4-p-Tolylpyrrolidine-3-carboxylic acid
CAS 1049976-10-4C12H15NO2
(3S,4R)-1-(tert-Butoxycarbonyl)-4-(p-tolyl)pyrrolidine-3-carboxylic acid chemical structure, C17H23NO4, CAS 959577-53-8
(3S,4R)-1-(tert-Butoxycarbonyl)-4-(p-tolyl)pyrrolidine-3-carboxylic acid
CAS 959577-53-8C17H23NO4
(3S,4R)-4-(2-Nitrophenyl)pyrrolidine-3-carboxylic acid hydrochloride chemical structure, C11H13ClN2O4, CAS 1049733-55-2
(3S,4R)-4-(2-Nitrophenyl)pyrrolidine-3-carboxylic acid hydrochloride
CAS 1049733-55-2C11H13ClN2O4
Trans-4-(2-nitrophenyl)pyrrolidine-3-carboxylic acid chemical structure, C11H12N2O4
Trans-4-(2-nitrophenyl)pyrrolidine-3-carboxylic acid
C11H12N2O4
Trans-1-Boc-4-(2-nitrophenyl)pyrrolidine-3-carboxylic acid chemical structure, C16H20N2O6, CAS 959577-51-6
Trans-1-Boc-4-(2-nitrophenyl)pyrrolidine-3-carboxylic acid
CAS 959577-51-6C16H20N2O6
(±)-Trans-4-(3-nitro-phenyl)-pyrrolidine-3-carboxylic acid-HCl chemical structure, C11H13ClN2O4, CAS 1049733-86-9
(±)-Trans-4-(3-nitro-phenyl)-pyrrolidine-3-carboxylic acid-HCl
CAS 1049733-86-9C11H13ClN2O4
Trans-4-(3-nitrophenyl)pyrrolidine-3-carboxylic acid chemical structure, C11H12N2O4, CAS 1049978-19-9
Trans-4-(3-nitrophenyl)pyrrolidine-3-carboxylic acid
CAS 1049978-19-9C11H12N2O4
Trans-1-Boc-4-(3-nitrophenyl)pyrrolidine-3-carboxylic acid chemical structure, C16H20N2O6
Trans-1-Boc-4-(3-nitrophenyl)pyrrolidine-3-carboxylic acid
C16H20N2O6
(±)-Trans-4-(4-nitro-phenyl)-pyrrolidine-3-carboxylic acid-HCl chemical structure, C11H13ClN2O4, CAS 1956321-89-3
(±)-Trans-4-(4-nitro-phenyl)-pyrrolidine-3-carboxylic acid-HCl
CAS 1956321-89-3C11H13ClN2O4
Trans-4-(4-nitrophenyl)pyrrolidine-3-carboxylic acid chemical structure, C11H12N2O4, CAS 1049978-30-4
Trans-4-(4-nitrophenyl)pyrrolidine-3-carboxylic acid
CAS 1049978-30-4C11H12N2O4
trans-1-Boc-4-(4-nitrophenyl)-pyrrolidine-3-carboxylic acid chemical structure, C16H20N2O6
trans-1-Boc-4-(4-nitrophenyl)-pyrrolidine-3-carboxylic acid
C16H20N2O6
(±)-Trans-4-(2,5-dichloro-phenyl)-pyrrolidine-3-carboxylic acid HCl chemical structure, C11H12Cl3NO2
(±)-Trans-4-(2,5-dichloro-phenyl)-pyrrolidine-3-carboxylic acid HCl
C11H12Cl3NO2
(3S,4R)-4-(2,5-Dichlorophenyl)pyrrolidine-3-carboxylic acid chemical structure, C11H11Cl2NO2, CAS 1049978-45-1
(3S,4R)-4-(2,5-Dichlorophenyl)pyrrolidine-3-carboxylic acid
CAS 1049978-45-1C11H11Cl2NO2
Boc-(+/-)-trans-4-(2,5-dichloro-phenyl)-pyrrolidine-3-carboxylic acid chemical structure, C16H19Cl2NO4, CAS 959577-44-7
Boc-(+/-)-trans-4-(2,5-dichloro-phenyl)-pyrrolidine-3-carboxylic acid
CAS 959577-44-7C16H19Cl2NO4
(3S,4R)-4-(2,3-Dichlorophenyl)pyrrolidine-3-carboxylic acid chemical structure, C11H11Cl2NO2
(3S,4R)-4-(2,3-Dichlorophenyl)pyrrolidine-3-carboxylic acid
C11H11Cl2NO2
Boc-(+/-)-trans-4-(2,3-dichloro-phenyl)-pyrrolidine-3-carboxylic acid chemical structure, C16H19Cl2NO4, CAS 959583-07-4
Boc-(+/-)-trans-4-(2,3-dichloro-phenyl)-pyrrolidine-3-carboxylic acid
CAS 959583-07-4C16H19Cl2NO4
(3S,4R)-4-(2-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid hydrochloride chemical structure, C12H13ClF3NO2, CAS 1049734-61-3
(3S,4R)-4-(2-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid hydrochloride
CAS 1049734-61-3C12H13ClF3NO2
Trans-1-Boc-4-(2-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid chemical structure, C17H20F3NO4
Trans-1-Boc-4-(2-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid
C17H20F3NO4
(3S,4R)-4-(3-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid hydrochloride chemical structure, C12H13ClF3NO2, CAS 1049978-65-5
(3S,4R)-4-(3-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid hydrochloride
CAS 1049978-65-5C12H13ClF3NO2
rac-(3R,4S)-4-[3-(Trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid chemical structure, C12H12F3NO2, CAS 2103402-71-5
rac-(3R,4S)-4-[3-(Trifluoromethyl)phenyl]pyrrolidine-3-carboxylic acid
CAS 2103402-71-5C12H12F3NO2
(3S,4R)-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid chemical structure, C17H20F3NO4, CAS 175272-69-2
(3S,4R)-1-(tert-Butoxycarbonyl)-4-(3-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid
CAS 175272-69-2C17H20F3NO4
(±)-Trans-4-(4-trifluoromethyl-phenyl)-pyrrolidine-3-carboxylic acid-HCl chemical structure, C12H13ClF3NO2
(±)-Trans-4-(4-trifluoromethyl-phenyl)-pyrrolidine-3-carboxylic acid-HCl
C12H13ClF3NO2
(3S,4R)-4-(4-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid chemical structure, C12H12F3NO2, CAS 1049978-66-6
(3S,4R)-4-(4-(Trifluoromethyl)phenyl)pyrrolidine-3-carboxylic acid
CAS 1049978-66-6C12H12F3NO2