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Murcko scaffold

3-Phenylpyrrolidine scaffold

4,373 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
4,373
With full pages
197
Scaffold SMILES

c1ccc(C2CCNC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenylpyrrolidine page
Murcko scaffold c1ccc(C2CCNC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 385 to 432 of 4,373 chemicals

(3S,4R)-Ethyl 1-(tert-butyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylate chemical structure, C17H23F2NO2, CAS 915158-39-3
(3S,4R)-Ethyl 1-(tert-butyl)-4-(2,4-difluorophenyl)pyrrolidine-3-carboxylate
CAS 915158-39-3C17H23F2NO2
Methyl (3S,4R)-4-phenylpyrrolidine-3-carboxylate chemical structure, C12H15NO2, CAS 156469-70-4
Methyl (3S,4R)-4-phenylpyrrolidine-3-carboxylate
CAS 156469-70-4C12H15NO2
rac-tert-Butyl (3R,4S)-3-amino-4-phenylpyrrolidine-1-carboxylate chemical structure, C15H22N2O2, CAS 1015070-53-7
rac-tert-Butyl (3R,4S)-3-amino-4-phenylpyrrolidine-1-carboxylate
CAS 1015070-53-7C15H22N2O2
Trans (+/-) 3-amino-4-(4-methylphenyl)pyrrolidine-1-carboxylic acid tert-butyl ester chemical structure, C16H24N2O2, CAS 1212106-36-9
Trans (+/-) 3-amino-4-(4-methylphenyl)pyrrolidine-1-carboxylic acid tert-butyl ester
CAS 1212106-36-9C16H24N2O2
3-(4-Methoxyphenyl)pyrrolidine oxalate chemical structure, C13H17NO5, CAS 96877-34-8
3-(4-Methoxyphenyl)pyrrolidine oxalate
CAS 96877-34-8C13H17NO5
3-(4-Chlorophenyl)pyrrolidine oxalate chemical structure, C12H14ClNO4, CAS 1188263-78-6
3-(4-Chlorophenyl)pyrrolidine oxalate
CAS 1188263-78-6C12H14ClNO4
3-(4-Fluorophenyl)pyrrolidine oxalate chemical structure, C12H14FNO4, CAS 1198416-84-0
3-(4-Fluorophenyl)pyrrolidine oxalate
CAS 1198416-84-0C12H14FNO4
3-(4-Methylphenyl)pyrrolidine oxalate chemical structure, C13H17NO4, CAS 1188264-10-9
3-(4-Methylphenyl)pyrrolidine oxalate
CAS 1188264-10-9C13H17NO4
3-(4-(Trifluoromethyl)phenyl)pyrrolidine hydrochloride chemical structure, C11H13ClF3N, CAS 1095545-12-2
3-(4-(Trifluoromethyl)phenyl)pyrrolidine hydrochloride
CAS 1095545-12-2C11H13ClF3N
3-(2-Chlorophenyl)pyrrolidine oxalate chemical structure, C12H14ClNO4, CAS 1217062-15-1
3-(2-Chlorophenyl)pyrrolidine oxalate
CAS 1217062-15-1C12H14ClNO4
3-(3-Phenylpyrrolidin-1-yl)propanoic acid chemical structure, C13H17NO2, CAS 116786-95-9
3-(3-Phenylpyrrolidin-1-yl)propanoic acid
CAS 116786-95-9C13H17NO2
Ethyl 3-phenylpyrrolidine-2-carboxylate chemical structure, C13H17NO2, CAS 1822420-65-4
Ethyl 3-phenylpyrrolidine-2-carboxylate
CAS 1822420-65-4C13H17NO2
tert-Butyl (3S,4R)-4-phenylpyrrolidin-3-ylcarbamate chemical structure, C15H22N2O2, CAS 351360-61-7
tert-Butyl (3S,4R)-4-phenylpyrrolidin-3-ylcarbamate
CAS 351360-61-7C15H22N2O2
trans (+/-) (4-(4-Methylphenyl)pyrrolidin-3-yl)carbamic acid tert-butyl ester chemical structure, C16H24N2O2, CAS 1212330-34-1
trans (+/-) (4-(4-Methylphenyl)pyrrolidin-3-yl)carbamic acid tert-butyl ester
CAS 1212330-34-1C16H24N2O2
(3S,4R)-Methyl 4-(4-methoxyphenyl)pyrrolidine-3-carboxylate chemical structure, C13H17NO3, CAS 750632-10-1
(3S,4R)-Methyl 4-(4-methoxyphenyl)pyrrolidine-3-carboxylate
CAS 750632-10-1C13H17NO3
Methyl (3S,4R)-4-(4-chlorophenyl)pyrrolidine-3-carboxylate hydrochloride chemical structure, C12H15Cl2NO2, CAS 862283-71-4
Methyl (3S,4R)-4-(4-chlorophenyl)pyrrolidine-3-carboxylate hydrochloride
CAS 862283-71-4C12H15Cl2NO2
Methyl (3S,4R)-4-(4-chlorophenyl)pyrrolidine-3-carboxylate chemical structure, C12H14ClNO2, CAS 862364-67-8
Methyl (3S,4R)-4-(4-chlorophenyl)pyrrolidine-3-carboxylate
CAS 862364-67-8C12H14ClNO2
trans-Methyl 4-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylate chemical structure, C13H14F3NO2, CAS 1212257-11-8
trans-Methyl 4-(4-(trifluoromethyl)phenyl)pyrrolidine-3-carboxylate
CAS 1212257-11-8C13H14F3NO2
Trans (+/-) 4-(2-chlorophenyl)pyrrolidine-3-methylcarboxylate, HCl chemical structure, C12H15Cl2NO2, CAS 1212327-46-2
Trans (+/-) 4-(2-chlorophenyl)pyrrolidine-3-methylcarboxylate, HCl
CAS 1212327-46-2C12H15Cl2NO2
rac-Methyl (3R,4S)-4-(2-chlorophenyl)pyrrolidine-3-carboxylate chemical structure, C12H14ClNO2, CAS 1212078-85-7
rac-Methyl (3R,4S)-4-(2-chlorophenyl)pyrrolidine-3-carboxylate
CAS 1212078-85-7C12H14ClNO2
(3R,4S)-4-(4-Bromophenyl)pyrrolidine-3-carboxylic acid hydrochloride chemical structure, C11H13BrClNO2, CAS 1217832-47-7
(3R,4S)-4-(4-Bromophenyl)pyrrolidine-3-carboxylic acid hydrochloride
CAS 1217832-47-7C11H13BrClNO2
3-[2-(Trifluoromethyl)phenyl]pyrrolidine chemical structure, C11H12F3N, CAS 916831-78-2
3-[2-(Trifluoromethyl)phenyl]pyrrolidine
CAS 916831-78-2C11H12F3N
3-(3-Chlorophenyl)pyrrolidine chemical structure, C10H12ClN, CAS 914299-59-5
3-(3-Chlorophenyl)pyrrolidine
CAS 914299-59-5C10H12ClN
3-[4-(Propan-2-yloxy)phenyl]pyrrolidine chemical structure, C13H19NO, CAS 1247687-64-4
3-[4-(Propan-2-yloxy)phenyl]pyrrolidine
CAS 1247687-64-4C13H19NO