CompoundList
Sign in
Murcko scaffold

3-Benzyl-2-mercapto-3H-quinazolin-4-one scaffold

66 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
66
With full pages
11
Scaffold SMILES

O=c1c2ccccc2[nH]c(=S)n1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Benzyl-2-mercapto-3H-quinazolin-4-one page
Murcko scaffold O=c1c2ccccc2[nH]c(=S)n1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

3-Benzyl-2-mercapto-3H-quinazolin-4-one chemical structure, C15H12N2OS, CAS 13906-05-3
3-Benzyl-2-mercapto-3H-quinazolin-4-one
CAS 13906-05-3C15H12N2OS
4-(4-Oxo-2-thioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl)-benzoic acid chemical structure, C16H12N2O3S, CAS 431906-56-8
4-(4-Oxo-2-thioxo-1,4-dihydro-2H-quinazolin-3-ylmethyl)-benzoic acid
CAS 431906-56-8C16H12N2O3S
3-(3-Methoxybenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one chemical structure, C16H14N2O2S, CAS 503425-25-0
3-(3-Methoxybenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
CAS 503425-25-0C16H14N2O2S
3-(2-Chlorobenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one chemical structure, C15H11ClN2OS, CAS 36120-41-9
3-(2-Chlorobenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
CAS 36120-41-9C15H11ClN2OS
3-[(4-Fluorophenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one chemical structure, C15H11FN2OS, CAS 431980-10-8
3-[(4-Fluorophenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS 431980-10-8C15H11FN2OS
2-Mercapto-3-(4-methoxybenzyl)quinazolin-4(3H)-one chemical structure, C16H14N2O2S, CAS 343618-41-7
2-Mercapto-3-(4-methoxybenzyl)quinazolin-4(3H)-one
CAS 343618-41-7C16H14N2O2S
3-[(2-Methoxyphenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one chemical structure, C16H14N2O2S, CAS 343618-27-9
3-[(2-Methoxyphenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS 343618-27-9C16H14N2O2S
3-(3-Chlorobenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one chemical structure, C15H11ClN2OS, CAS 35976-97-7
3-(3-Chlorobenzyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one
CAS 35976-97-7C15H11ClN2OS
Methyl 3-[(2-chlorophenyl)methyl]-4-oxo-2-sulfanyl-3,4-dihydroquinazoline-7-carboxylate chemical structure, C17H13ClN2O3S, CAS 361150-59-6
Methyl 3-[(2-chlorophenyl)methyl]-4-oxo-2-sulfanyl-3,4-dihydroquinazoline-7-carboxylate
CAS 361150-59-6C17H13ClN2O3S
Methyl 3-benzyl-2-mercapto-4-oxo-3,4-dihydroquinazoline-7-carboxylate chemical structure, C17H14N2O3S, CAS 310448-89-6
Methyl 3-benzyl-2-mercapto-4-oxo-3,4-dihydroquinazoline-7-carboxylate
CAS 310448-89-6C17H14N2O3S
Methyl 3-(3-methoxybenzyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate chemical structure, C18H16N2O4S, CAS 725691-84-9
Methyl 3-(3-methoxybenzyl)-4-oxo-2-thioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylate
CAS 725691-84-9C18H16N2O4S
3-[(4-Methylphenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one chemical structure, C16H14N2OS, CAS 35977-05-0
3-[(4-Methylphenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS 35977-05-0C16H14N2OS
3-Benzyl-7-chloro-2-sulfanyl-3,4-dihydroquinazolin-4-one chemical structure, C15H11ClN2OS, CAS 422274-69-9
3-Benzyl-7-chloro-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS 422274-69-9C15H11ClN2OS
3-[(3,4-Dimethoxyphenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one chemical structure, C17H16N2O3S, CAS 723332-67-0
3-[(3,4-Dimethoxyphenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS 723332-67-0C17H16N2O3S
3-(4-Chloro-benzyl)-2-mercapto-3H-quinazolin-4-one chemical structure, C15H11ClN2OS, CAS 35976-99-9
3-(4-Chloro-benzyl)-2-mercapto-3H-quinazolin-4-one
CAS 35976-99-9C15H11ClN2OS
3-Benzyl-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylic acid chemical structure, C16H12N2O3S, CAS 309940-71-4
3-Benzyl-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylic acid
CAS 309940-71-4C16H12N2O3S
6-Bromo-3-[(2-chlorophenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one chemical structure, C15H10BrClN2OS, CAS 35977-19-6
6-Bromo-3-[(2-chlorophenyl)methyl]-2-sulfanyl-3,4-dihydroquinazolin-4-one
CAS 35977-19-6C15H10BrClN2OS
3-[(4-Chlorophenyl)methyl]-6,7-diethoxy-2-sulfanylidene-1H-quinazolin-4-one chemical structure, C19H19ClN2O3S, CAS 689769-67-3
3-[(4-Chlorophenyl)methyl]-6,7-diethoxy-2-sulfanylidene-1H-quinazolin-4-one
CAS 689769-67-3C19H19ClN2O3S
3-[(3-Chlorophenyl)methyl]-6-fluoro-2-sulfanylidene-1H-quinazolin-4-one chemical structure, C15H10ClFN2OS, CAS 422274-43-9
3-[(3-Chlorophenyl)methyl]-6-fluoro-2-sulfanylidene-1H-quinazolin-4-one
CAS 422274-43-9C15H10ClFN2OS
6-Chloro-3-[(2-methoxyphenyl)methyl]-2-sulfanylidene-1H-quinazolin-4-one chemical structure, C16H13ClN2O2S, CAS 422527-22-8
6-Chloro-3-[(2-methoxyphenyl)methyl]-2-sulfanylidene-1H-quinazolin-4-one
CAS 422527-22-8C16H13ClN2O2S
N-(3-Methylbutyl)-4-[(4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)methyl]benzamide chemical structure, C21H23N3O2S, CAS 422282-11-9
N-(3-Methylbutyl)-4-[(4-oxo-2-sulfanylidene-1H-quinazolin-3-yl)methyl]benzamide
CAS 422282-11-9C21H23N3O2S
Methyl 3-[(3-chlorophenyl)methyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylate chemical structure, C17H13ClN2O3S, CAS 361150-60-9
Methyl 3-[(3-chlorophenyl)methyl]-4-oxo-2-sulfanylidene-1H-quinazoline-7-carboxylate
CAS 361150-60-9C17H13ClN2O3S
6-Chloro-3-[(4-fluorophenyl)methyl]-2-sulfanylidene-1H-quinazolin-4-one chemical structure, C15H10ClFN2OS, CAS 422527-16-0
6-Chloro-3-[(4-fluorophenyl)methyl]-2-sulfanylidene-1H-quinazolin-4-one
CAS 422527-16-0C15H10ClFN2OS
3-[(2-Chlorophenyl)methyl]-4-oxo-2-sulfanyl-3,4-dihydroquinazoline-7-carboxylic acid chemical structure, C16H11ClN2O3S, CAS 361150-31-4
3-[(2-Chlorophenyl)methyl]-4-oxo-2-sulfanyl-3,4-dihydroquinazoline-7-carboxylic acid
CAS 361150-31-4C16H11ClN2O3S