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Murcko scaffold

1-(2-Phenoxyethyl)piperazine scaffold

238 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
238
With full pages
1
Scaffold SMILES

c1ccc(OCCN2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Phenoxyethyl)piperazine page
Murcko scaffold c1ccc(OCCN2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 193 to 238 of 238 chemicals

tert-Butyl 4-[2-(2-cyanophenoxy)ethyl]piperazine-1-carboxylate chemical structure, C18H25N3O3, CAS 2680680-99-1
tert-Butyl 4-[2-(2-cyanophenoxy)ethyl]piperazine-1-carboxylate
CAS 2680680-99-1C18H25N3O3
4-(2-(2-Fluorophenoxy)ethyl)piperazine-1-carboximidamide chemical structure, C13H19FN4O, CAS 2819384-01-3
4-(2-(2-Fluorophenoxy)ethyl)piperazine-1-carboximidamide
CAS 2819384-01-3C13H19FN4O
tert-Butyl 4-[2-(4-amino-2-chlorophenoxy)ethyl]piperazine-1-carboxylate chemical structure, C17H26ClN3O3, CAS 3078332-04-1
tert-Butyl 4-[2-(4-amino-2-chlorophenoxy)ethyl]piperazine-1-carboxylate
CAS 3078332-04-1C17H26ClN3O3
tert-Butyl 4-(2-(2-bromo-4-nitrophenoxy)ethyl)-3-methylpiperazine-1-carboxylate chemical structure, C18H26BrN3O5, CAS 3078588-08-3
tert-Butyl 4-(2-(2-bromo-4-nitrophenoxy)ethyl)-3-methylpiperazine-1-carboxylate
CAS 3078588-08-3C18H26BrN3O5
tert-Butyl 4-(2-(4-iodophenoxy)ethyl)-2-methylpiperazine-1-carboxylate chemical structure, C18H27IN2O3, CAS 3078585-56-2
tert-Butyl 4-(2-(4-iodophenoxy)ethyl)-2-methylpiperazine-1-carboxylate
CAS 3078585-56-2C18H27IN2O3
3-(4-(2-(4-(tert-Butoxycarbonyl)-3-methylpiperazin-1-yl)ethoxy)phenyl)propanoic acid chemical structure, C21H32N2O5, CAS 3078352-08-3
3-(4-(2-(4-(tert-Butoxycarbonyl)-3-methylpiperazin-1-yl)ethoxy)phenyl)propanoic acid
CAS 3078352-08-3C21H32N2O5
3-(4-(2-(4-(tert-Butoxycarbonyl)-2-methylpiperazin-1-yl)ethoxy)phenyl)propanoic acid chemical structure, C21H32N2O5, CAS 3078586-11-2
3-(4-(2-(4-(tert-Butoxycarbonyl)-2-methylpiperazin-1-yl)ethoxy)phenyl)propanoic acid
CAS 3078586-11-2C21H32N2O5
3-Methyl-1-(2-(4-nitrophenoxy)ethyl)piperazine dihydrochloride chemical structure, C13H21Cl2N3O3, CAS 3078585-71-1
3-Methyl-1-(2-(4-nitrophenoxy)ethyl)piperazine dihydrochloride
CAS 3078585-71-1C13H21Cl2N3O3
2-Methyl-1-(2-(4-nitrophenoxy)ethyl)piperazine dihydrochloride chemical structure, C13H21Cl2N3O3, CAS 3078352-77-6
2-Methyl-1-(2-(4-nitrophenoxy)ethyl)piperazine dihydrochloride
CAS 3078352-77-6C13H21Cl2N3O3
tert-Butyl 4-(2-(4-aminophenoxy)ethyl)-3-methylpiperazine-1-carboxylate chemical structure, C18H29N3O3, CAS 3078334-75-2
tert-Butyl 4-(2-(4-aminophenoxy)ethyl)-3-methylpiperazine-1-carboxylate
CAS 3078334-75-2C18H29N3O3
tert-Butyl 4-(2-(3-aminophenoxy)ethyl)-2-methylpiperazine-1-carboxylate chemical structure, C18H29N3O3, CAS 3078345-85-1
tert-Butyl 4-(2-(3-aminophenoxy)ethyl)-2-methylpiperazine-1-carboxylate
CAS 3078345-85-1C18H29N3O3
tert-Butyl 4-(2-(3-aminophenoxy)ethyl)-3-methylpiperazine-1-carboxylate chemical structure, C18H29N3O3, CAS 3078346-03-6
tert-Butyl 4-(2-(3-aminophenoxy)ethyl)-3-methylpiperazine-1-carboxylate
CAS 3078346-03-6C18H29N3O3
tert-Butyl 4-(2-(3-bromophenoxy)ethyl)-2-methylpiperazine-1-carboxylate chemical structure, C18H27BrN2O3, CAS 3078335-84-6
tert-Butyl 4-(2-(3-bromophenoxy)ethyl)-2-methylpiperazine-1-carboxylate
CAS 3078335-84-6C18H27BrN2O3
tert-Butyl 4-(2-(3-iodophenoxy)ethyl)-2-methylpiperazine-1-carboxylate chemical structure, C18H27IN2O3, CAS 3078586-09-8
tert-Butyl 4-(2-(3-iodophenoxy)ethyl)-2-methylpiperazine-1-carboxylate
CAS 3078586-09-8C18H27IN2O3
tert-Butyl 4-(2-(3-bromophenoxy)ethyl)-3-methylpiperazine-1-carboxylate chemical structure, C18H27BrN2O3, CAS 3078346-44-5
tert-Butyl 4-(2-(3-bromophenoxy)ethyl)-3-methylpiperazine-1-carboxylate
CAS 3078346-44-5C18H27BrN2O3
tert-Butyl 4-(2-(3-iodophenoxy)ethyl)-3-methylpiperazine-1-carboxylate chemical structure, C18H27IN2O3, CAS 3078335-92-6
tert-Butyl 4-(2-(3-iodophenoxy)ethyl)-3-methylpiperazine-1-carboxylate
CAS 3078335-92-6C18H27IN2O3
tert-Butyl 4-(2-(3-bromo-5-(methoxycarbonyl)phenoxy)ethyl)-2-methylpiperazine-1-carboxylate chemical structure, C20H29BrN2O5, CAS 3078351-25-1
tert-Butyl 4-(2-(3-bromo-5-(methoxycarbonyl)phenoxy)ethyl)-2-methylpiperazine-1-carboxylate
CAS 3078351-25-1C20H29BrN2O5
tert-Butyl 4-(2-(3-bromo-5-(methoxycarbonyl)phenoxy)ethyl)-3-methylpiperazine-1-carboxylate chemical structure, C20H29BrN2O5, CAS 3078586-49-6
tert-Butyl 4-(2-(3-bromo-5-(methoxycarbonyl)phenoxy)ethyl)-3-methylpiperazine-1-carboxylate
CAS 3078586-49-6C20H29BrN2O5
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-methylbenzoic acid chemical structure, C16H24N2O3, CAS 3078411-71-6
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-methylbenzoic acid
CAS 3078411-71-6C16H24N2O3
3-Methyl-4-(2-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)ethoxy)benzoic acid chemical structure, C16H21F3N2O3, CAS 3078397-53-9
3-Methyl-4-(2-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)ethoxy)benzoic acid
CAS 3078397-53-9C16H21F3N2O3
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-fluorobenzoic acid chemical structure, C15H21FN2O3, CAS 3078387-50-2
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-fluorobenzoic acid
CAS 3078387-50-2C15H21FN2O3
3-Fluoro-4-(2-(4-isopropylpiperazin-1-yl)ethoxy)benzoic acid chemical structure, C16H23FN2O3, CAS 3078390-66-3
3-Fluoro-4-(2-(4-isopropylpiperazin-1-yl)ethoxy)benzoic acid
CAS 3078390-66-3C16H23FN2O3
3-Fluoro-4-(2-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)ethoxy)benzoic acid chemical structure, C15H18F4N2O3, CAS 3078387-55-7
3-Fluoro-4-(2-(4-(2,2,2-trifluoroethyl)piperazin-1-yl)ethoxy)benzoic acid
CAS 3078387-55-7C15H18F4N2O3
4-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)-3-methylbenzoic acid chemical structure, C19H28N2O5, CAS 3078408-54-2
4-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)-3-methylbenzoic acid
CAS 3078408-54-2C19H28N2O5