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Murcko scaffold

1-(2-Phenoxyethyl)piperazine scaffold

238 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
238
With full pages
14
Scaffold SMILES

c1ccc(OCCN2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Phenoxyethyl)piperazine page
Murcko scaffold c1ccc(OCCN2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 238 chemicals

tert-Butyl 4-[2-(5-chloro-4-methyl-2-nitrophenoxy)ethyl]piperazine-1-carboxylate chemical structure, C18H26ClN3O5, CAS 862874-10-0
tert-Butyl 4-[2-(5-chloro-4-methyl-2-nitrophenoxy)ethyl]piperazine-1-carboxylate
CAS 862874-10-0C18H26ClN3O5
tert-Butyl 4-[2-(2-amino-5-chloro-4-methylphenoxy)ethyl]piperazine-1-carboxylate chemical structure, C18H28ClN3O3, CAS 862874-16-6
tert-Butyl 4-[2-(2-amino-5-chloro-4-methylphenoxy)ethyl]piperazine-1-carboxylate
CAS 862874-16-6C18H28ClN3O3
tert-Butyl 4-{2-[2-amino-4-(trifluoromethyl)phenoxy]ethyl}piperazine-1-carboxylate chemical structure, C18H26F3N3O3, CAS 862873-93-6
tert-Butyl 4-{2-[2-amino-4-(trifluoromethyl)phenoxy]ethyl}piperazine-1-carboxylate
CAS 862873-93-6C18H26F3N3O3
tert-Butyl 4-(2-(4-aminophenoxy)ethyl)piperazine-1-carboxylate chemical structure, C17H27N3O3, CAS 862874-77-9
tert-Butyl 4-(2-(4-aminophenoxy)ethyl)piperazine-1-carboxylate
CAS 862874-77-9C17H27N3O3
1-(2-(4-Bromo-3-fluorophenoxy)ethyl)-4-methylpiperazine chemical structure, C13H18BrFN2O, CAS 897017-01-5
1-(2-(4-Bromo-3-fluorophenoxy)ethyl)-4-methylpiperazine
CAS 897017-01-5C13H18BrFN2O
(3-(2-(4-Methylpiperazin-1-yl)ethoxy)phenyl)boronic acid chemical structure, C13H21BN2O3, CAS 1170697-43-4
(3-(2-(4-Methylpiperazin-1-yl)ethoxy)phenyl)boronic acid
CAS 1170697-43-4C13H21BN2O3
4-(2-(4-Methylpiperazin-1-yl)ethoxy)-2-nitroaniline chemical structure, C13H20N4O3, CAS 1018895-62-9
4-(2-(4-Methylpiperazin-1-yl)ethoxy)-2-nitroaniline
CAS 1018895-62-9C13H20N4O3
4-(2-(4-Methylpiperazin-1-yl)ethoxy)benzene-1,2-diamine chemical structure, C13H22N4O, CAS 1018895-63-0
4-(2-(4-Methylpiperazin-1-yl)ethoxy)benzene-1,2-diamine
CAS 1018895-63-0C13H22N4O
tert-Butyl 4-(2-(3,4-diaminophenoxy)ethyl)piperazine-1-carboxylate chemical structure, C17H28N4O3, CAS 1018895-56-1
tert-Butyl 4-(2-(3,4-diaminophenoxy)ethyl)piperazine-1-carboxylate
CAS 1018895-56-1C17H28N4O3
1-(2-Ethoxyethyl)-4-{2-[3-(trifluoromethyl)phenoxy]ethyl}piperazine chemical structure, C17H25F3N2O2, CAS 918481-68-2
1-(2-Ethoxyethyl)-4-{2-[3-(trifluoromethyl)phenoxy]ethyl}piperazine
CAS 918481-68-2C17H25F3N2O2
2-(Methyloxy)-4-{[2-(4-methyl-1-piperazinyl)ethyl]oxy}aniline chemical structure, C14H23N3O2, CAS 1021432-13-2
2-(Methyloxy)-4-{[2-(4-methyl-1-piperazinyl)ethyl]oxy}aniline
CAS 1021432-13-2C14H23N3O2
1-Methyl-4-(2-{[3-(methyloxy)-4-nitrophenyl]oxy}ethyl)piperazine chemical structure, C14H21N3O4, CAS 1116231-70-9
1-Methyl-4-(2-{[3-(methyloxy)-4-nitrophenyl]oxy}ethyl)piperazine
CAS 1116231-70-9C14H21N3O4
1-(2-(4-Bromophenoxy)ethyl)-4-ethylpiperazine chemical structure, C14H21BrN2O, CAS 1293203-47-0
1-(2-(4-Bromophenoxy)ethyl)-4-ethylpiperazine
CAS 1293203-47-0C14H21BrN2O
1-(2-(3-Bromophenoxy)ethyl)-4-methylpiperazine chemical structure, C13H19BrN2O, CAS 1308596-49-7
1-(2-(3-Bromophenoxy)ethyl)-4-methylpiperazine
CAS 1308596-49-7C13H19BrN2O
(3-(2-(4-Ethylpiperazin-1-yl)ethoxy)phenyl)boronic acid chemical structure, C14H23BN2O3, CAS 1334331-78-0
(3-(2-(4-Ethylpiperazin-1-yl)ethoxy)phenyl)boronic acid
CAS 1334331-78-0C14H23BN2O3
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)phenylboronic acid chemical structure, C14H23BN2O3, CAS 1313736-64-9
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)phenylboronic acid
CAS 1313736-64-9C14H23BN2O3
4-(2-(4-Methylpiperazin-1-yl)ethoxy)phenylboronic acid chemical structure, C13H21BN2O3, CAS 1312921-38-2
4-(2-(4-Methylpiperazin-1-yl)ethoxy)phenylboronic acid
CAS 1312921-38-2C13H21BN2O3
1-[2-(4-Bromophenoxy)ethyl]-2-methylpiperazine chemical structure, C13H19BrN2O, CAS 1240570-59-5
1-[2-(4-Bromophenoxy)ethyl]-2-methylpiperazine
CAS 1240570-59-5C13H19BrN2O
1-[2-(4-Fluorophenoxy)ethyl]-2-methylpiperazine chemical structure, C13H19FN2O, CAS 1240571-12-3
1-[2-(4-Fluorophenoxy)ethyl]-2-methylpiperazine
CAS 1240571-12-3C13H19FN2O
2-Methyl-1-(2-phenoxyethyl)piperazine chemical structure, C13H20N2O, CAS 1240573-26-5
2-Methyl-1-(2-phenoxyethyl)piperazine
CAS 1240573-26-5C13H20N2O
3-[2-(4-Methylsulfonylpiperazin-1-yl)ethoxy]aniline chemical structure, C13H21N3O3S, CAS 1211821-10-1
3-[2-(4-Methylsulfonylpiperazin-1-yl)ethoxy]aniline
CAS 1211821-10-1C13H21N3O3S
2-tert-Butyl-1-(2-phenoxyethyl)piperazine chemical structure, C16H26N2O, CAS 1379065-77-6
2-tert-Butyl-1-(2-phenoxyethyl)piperazine
CAS 1379065-77-6C16H26N2O
1-[2-(3-Bromophenoxy)ethyl]-2,5,5-trimethylpiperazine chemical structure, C15H23BrN2O, CAS 1378511-59-1
1-[2-(3-Bromophenoxy)ethyl]-2,5,5-trimethylpiperazine
CAS 1378511-59-1C15H23BrN2O
tert-Butyl 4-(2-(4-amino-3-nitrophenoxy)ethyl)piperazine-1-carboxylate chemical structure, C17H26N4O5, CAS 1018895-55-0
tert-Butyl 4-(2-(4-amino-3-nitrophenoxy)ethyl)piperazine-1-carboxylate
CAS 1018895-55-0C17H26N4O5