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Murcko scaffold

1-(2-Phenoxyethyl)piperazine scaffold

238 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
238
With full pages
14
Scaffold SMILES

c1ccc(OCCN2CCNCC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-(2-Phenoxyethyl)piperazine page
Murcko scaffold c1ccc(OCCN2CCNCC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 145 to 192 of 238 chemicals

Piperazine, 1-[1-methyl-2-(4-methylphenoxy)ethyl]-, hydrochloride (1:2) chemical structure, C14H24Cl2N2O, CAS 1177346-04-1
Piperazine, 1-[1-methyl-2-(4-methylphenoxy)ethyl]-, hydrochloride (1:2)
CAS 1177346-04-1C14H24Cl2N2O
Piperazine, 1-[2-(2-ethoxyphenoxy)-1-methylethyl]-, hydrochloride (1:2) chemical structure, C15H26Cl2N2O2, CAS 1177321-31-1
Piperazine, 1-[2-(2-ethoxyphenoxy)-1-methylethyl]-, hydrochloride (1:2)
CAS 1177321-31-1C15H26Cl2N2O2
3-(2-Piperazin-1-ylethoxy)aniline chemical structure, C12H19N3O, CAS 1211825-18-1
3-(2-Piperazin-1-ylethoxy)aniline
CAS 1211825-18-1C12H19N3O
2-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-(trifluoromethyl)benzenamine chemical structure, C14H20F3N3O, CAS 1174295-89-6
2-[2-(4-Methyl-1-piperazinyl)ethoxy]-5-(trifluoromethyl)benzenamine
CAS 1174295-89-6C14H20F3N3O
3-Methoxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoic acid chemical structure, C15H22N2O4, CAS 1548432-85-4
3-Methoxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoic acid
CAS 1548432-85-4C15H22N2O4
4-Methoxy-3-(2-(4-methylpiperazin-1-yl)ethoxy)aniline chemical structure, C14H23N3O2, CAS 1413919-90-0
4-Methoxy-3-(2-(4-methylpiperazin-1-yl)ethoxy)aniline
CAS 1413919-90-0C14H23N3O2
3,5-Dibromo-4-[2-(4-methylpiperazin-1-yl)ethoxy]aniline chemical structure, C13H19Br2N3O, CAS 744961-77-1
3,5-Dibromo-4-[2-(4-methylpiperazin-1-yl)ethoxy]aniline
CAS 744961-77-1C13H19Br2N3O
4-Methyl-3-[2-(4-methylpiperazin-1-yl)ethoxy]aniline chemical structure, C14H23N3O, CAS 1453213-92-7
4-Methyl-3-[2-(4-methylpiperazin-1-yl)ethoxy]aniline
CAS 1453213-92-7C14H23N3O
1-[2-(4-Bromo-3-methylphenoxy)ethyl]piperazine chemical structure, C13H19BrN2O, CAS 401801-50-1
1-[2-(4-Bromo-3-methylphenoxy)ethyl]piperazine
CAS 401801-50-1C13H19BrN2O
1-[2-(4-Nitrophenoxy)ethyl]-4-prop-2-ynylpiperazine chemical structure, C15H19N3O3, CAS 1465336-47-3
1-[2-(4-Nitrophenoxy)ethyl]-4-prop-2-ynylpiperazine
CAS 1465336-47-3C15H19N3O3
1-[2-(2-Bromo-5-chlorophenoxy)ethyl]-4-methylpiperazine chemical structure, C13H18BrClN2O, CAS 1611444-68-8
1-[2-(2-Bromo-5-chlorophenoxy)ethyl]-4-methylpiperazine
CAS 1611444-68-8C13H18BrClN2O
(3-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)phenyl)boronic acid chemical structure, C17H27BN2O5, CAS 1704063-53-5
(3-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)phenyl)boronic acid
CAS 1704063-53-5C17H27BN2O5
3-Fluoro-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenylboronic acid chemical structure, C13H20BFN2O3, CAS 1704064-12-9
3-Fluoro-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenylboronic acid
CAS 1704064-12-9C13H20BFN2O3
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-fluorophenylboronic acid chemical structure, C14H22BFN2O3, CAS 1704064-13-0
4-(2-(4-Ethylpiperazin-1-yl)ethoxy)-3-fluorophenylboronic acid
CAS 1704064-13-0C14H22BFN2O3
4-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)-3-fluorophenylboronic acid chemical structure, C17H26BFN2O5, CAS 1704064-14-1
4-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)-3-fluorophenylboronic acid
CAS 1704064-14-1C17H26BFN2O5
(3-Chloro-4-(2-(piperazin-1-yl)ethoxy)phenyl)boronic acid chemical structure, C12H18BClN2O3, CAS 1704074-12-3
(3-Chloro-4-(2-(piperazin-1-yl)ethoxy)phenyl)boronic acid
CAS 1704074-12-3C12H18BClN2O3
(4-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)-3-chlorophenyl)boronic acid chemical structure, C17H26BClN2O5, CAS 1704074-18-9
(4-(2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)ethoxy)-3-chlorophenyl)boronic acid
CAS 1704074-18-9C17H26BClN2O5
(3-Chloro-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)boronic acid chemical structure, C13H20BClN2O3, CAS 1704074-20-3
(3-Chloro-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)boronic acid
CAS 1704074-20-3C13H20BClN2O3
(3-Chloro-4-(2-(4-ethylpiperazin-1-yl)ethoxy)phenyl)boronic acid chemical structure, C14H22BClN2O3, CAS 1704074-31-6
(3-Chloro-4-(2-(4-ethylpiperazin-1-yl)ethoxy)phenyl)boronic acid
CAS 1704074-31-6C14H22BClN2O3
1-(2-(4-Bromo-2-chlorophenoxy)ethyl)-4-methylpiperazine chemical structure, C13H18BrClN2O, CAS 401801-83-0
1-(2-(4-Bromo-2-chlorophenoxy)ethyl)-4-methylpiperazine
CAS 401801-83-0C13H18BrClN2O
tert-Butyl 4-(2-(4-bromo-2-chlorophenoxy)ethyl)piperazine-1-carboxylate chemical structure, C17H24BrClN2O3, CAS 1704074-14-5
tert-Butyl 4-(2-(4-bromo-2-chlorophenoxy)ethyl)piperazine-1-carboxylate
CAS 1704074-14-5C17H24BrClN2O3
2-(4-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperazin-1-yl)ethanol chemical structure, C14H20BrFN2O2, CAS 1704081-70-8
2-(4-(2-(4-Bromo-2-fluorophenoxy)ethyl)piperazin-1-yl)ethanol
CAS 1704081-70-8C14H20BrFN2O2
2-(4-(2-(4-Bromo-2-chlorophenoxy)ethyl)piperazin-1-yl)ethanol chemical structure, C14H20BrClN2O2, CAS 1704074-29-2
2-(4-(2-(4-Bromo-2-chlorophenoxy)ethyl)piperazin-1-yl)ethanol
CAS 1704074-29-2C14H20BrClN2O2
1-(2-(4-Bromo-2-fluorophenoxy)ethyl)-4-methylpiperazine chemical structure, C13H18BrFN2O, CAS 1704081-41-3
1-(2-(4-Bromo-2-fluorophenoxy)ethyl)-4-methylpiperazine
CAS 1704081-41-3C13H18BrFN2O