Murcko scaffold
Ring system with 2 rings and 18 atoms
37 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 18
- Chemicals
- 37
- With full pages
- 4
Scaffold SMILES
O=C(COC(=O)c1ccco1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 37 of 37 chemicals
![{[4-(Ethoxycarbonyl)phenyl]carbamoyl}methyl furan-2-carboxylate chemical structure, C16H15NO6, CAS 380191-77-5](/s/UEZVFOFZESYCKL-UHFFFAOYSA-N.svg)
{[4-(Ethoxycarbonyl)phenyl]carbamoyl}methyl furan-2-carboxylate
CAS 380191-77-5C16H15NO6
![[2-(3-Chloro-4-methoxyanilino)-2-oxoethyl] 5-nitrofuran-2-carboxylate chemical structure, C14H11ClN2O7, CAS 385404-16-0](/s/ZDNUXKIAIPOJLN-UHFFFAOYSA-N.svg)
[2-(3-Chloro-4-methoxyanilino)-2-oxoethyl] 5-nitrofuran-2-carboxylate
CAS 385404-16-0C14H11ClN2O7
![[2-(3,4-Dimethylanilino)-2-oxoethyl] furan-2-carboxylate chemical structure, C15H15NO4, CAS 380184-62-3](/s/OMKCEEUSBRJWOY-UHFFFAOYSA-N.svg)
[2-(3,4-Dimethylanilino)-2-oxoethyl] furan-2-carboxylate
CAS 380184-62-3C15H15NO4
![[2-(4-Bromo-2-fluoroanilino)-2-oxoethyl] 5-nitrofuran-2-carboxylate chemical structure, C13H8BrFN2O6, CAS 380484-05-9](/s/IQYHFAFWNQQSAZ-UHFFFAOYSA-N.svg)
[2-(4-Bromo-2-fluoroanilino)-2-oxoethyl] 5-nitrofuran-2-carboxylate
CAS 380484-05-9C13H8BrFN2O6
![[2-(5-Chloro-2-methoxyanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate chemical structure, C14H11BrClNO5, CAS 380563-30-4](/s/LPMYKJKGISGJIA-UHFFFAOYSA-N.svg)
[2-(5-Chloro-2-methoxyanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate
CAS 380563-30-4C14H11BrClNO5
2-(Mesitylamino)-2-oxoethyl 2-furoate
CAS 378226-52-9C16H17NO4
![[2-(2,6-Dimethylanilino)-2-oxoethyl] 5-nitrofuran-2-carboxylate chemical structure, C15H14N2O6, CAS 385403-50-9](/s/KUCGIUUNNMUQSL-UHFFFAOYSA-N.svg)
[2-(2,6-Dimethylanilino)-2-oxoethyl] 5-nitrofuran-2-carboxylate
CAS 385403-50-9C15H14N2O6
![2-[(2,6-Difluorophenyl)amino]-2-oxoethyl 5-nitro-2-furancarboxylate chemical structure, C13H8F2N2O6, CAS 385404-10-4](/s/WQCZFZINSMTMHN-UHFFFAOYSA-N.svg)
2-[(2,6-Difluorophenyl)amino]-2-oxoethyl 5-nitro-2-furancarboxylate
CAS 385404-10-4C13H8F2N2O6
![[(4-Ethoxyphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C15H14BrNO5, CAS 733006-15-0](/s/UAYVHCGYZPZNDW-UHFFFAOYSA-N.svg)
[(4-Ethoxyphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 733006-15-0C15H14BrNO5
![[(4-Chloro-2-fluorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C13H8BrClFNO4, CAS 436111-09-0](/s/AVQPOVXDIABVIW-UHFFFAOYSA-N.svg)
[(4-Chloro-2-fluorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 436111-09-0C13H8BrClFNO4
![[(3,4-Dimethoxyphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C15H14BrNO6, CAS 733007-18-6](/s/YHJCSMNRODVJGP-UHFFFAOYSA-N.svg)
[(3,4-Dimethoxyphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 733007-18-6C15H14BrNO6
![[(3-Chlorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C13H9BrClNO4, CAS 386277-95-8](/s/SXIMTWZXEHKJRL-UHFFFAOYSA-N.svg)
[(3-Chlorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386277-95-8C13H9BrClNO4
![[(3-Fluoro-4-methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C14H11BrFNO4, CAS 733025-22-4](/s/DNDIHXNSVYBFIX-UHFFFAOYSA-N.svg)
[(3-Fluoro-4-methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 733025-22-4C14H11BrFNO4
![[Methyl(phenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C14H12BrNO4, CAS 386276-93-3](/s/NMVKWWLTZNYJOV-UHFFFAOYSA-N.svg)
[Methyl(phenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386276-93-3C14H12BrNO4
![[2-(3-Chloro-4-fluoroanilino)-2-oxoethyl] 5-methylfuran-2-carboxylate chemical structure, C14H11ClFNO4, CAS 848228-05-7](/s/KMYNVKRIFHJCGA-UHFFFAOYSA-N.svg)
[2-(3-Chloro-4-fluoroanilino)-2-oxoethyl] 5-methylfuran-2-carboxylate
CAS 848228-05-7C14H11ClFNO4
![[(2,3-Dimethylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C15H14BrNO4, CAS 386276-98-8](/s/BACFWXJOCVVYDA-UHFFFAOYSA-N.svg)
[(2,3-Dimethylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386276-98-8C15H14BrNO4
![[(3-Methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C14H12BrNO4, CAS 386277-07-2](/s/FFWALDLXMBCWBG-UHFFFAOYSA-N.svg)
[(3-Methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386277-07-2C14H12BrNO4
![[(2-Methoxy-5-methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C15H14BrNO5, CAS 386277-08-3](/s/HOXYKBUKIDGYRZ-UHFFFAOYSA-N.svg)
[(2-Methoxy-5-methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386277-08-3C15H14BrNO5
2-((2,6-Dimethylphenyl)amino)-2-oxoethyl 5-bromofuran-2-carboxylate
CAS 386277-09-4C15H14BrNO4
![[(2-Chlorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C13H9BrClNO4, CAS 386277-12-9](/s/VAGJROBAWVJGLV-UHFFFAOYSA-N.svg)
[(2-Chlorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386277-12-9C13H9BrClNO4
![[2-(2,4-Dimethoxyanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate chemical structure, C15H14BrNO6, CAS 1003272-84-1](/s/VPYRIHRVUKMRER-UHFFFAOYSA-N.svg)
[2-(2,4-Dimethoxyanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate
CAS 1003272-84-1C15H14BrNO6
![[(2-Methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate chemical structure, C14H12BrNO4, CAS 386277-16-3](/s/BJDHPUYHPKUSJY-UHFFFAOYSA-N.svg)
[(2-Methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate
CAS 386277-16-3C14H12BrNO4
2-Oxo-2-(p-tolylamino)ethyl 5-bromofuran-2-carboxylate
CAS 386277-18-5C14H12BrNO4
![[2-(4-Fluoroanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate chemical structure, C13H9BrFNO4, CAS 386277-85-6](/s/LGILSQUFHJPXJO-UHFFFAOYSA-N.svg)
[2-(4-Fluoroanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate
CAS 386277-85-6C13H9BrFNO4
- 2-((4-Ethylphenyl)amino)-2-oxoethyl 5-bromofuran-2-carboxylate386277-99-2C15H14BrNO4
- [(2,5-Dimethylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate386278-02-0C15H14BrNO4
- [2-(2-Methoxyanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate474272-94-1C14H12BrNO5
- {[2-(Trifluoromethyl)phenyl]carbamoyl}methyl 5-bromofuran-2-carboxylate848597-50-2C14H9BrF3NO4
- [2-(4-Fluoro-2-nitroanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate733007-33-5C13H8BrFN2O6
- {[2-(Methoxycarbonyl)phenyl]carbamoyl}methyl 5-bromofuran-2-carboxylate438032-83-8C15H12BrNO6
- [2-(2-Chloro-4-fluoroanilino)-2-oxoethyl] 5-bromofuran-2-carboxylate386277-40-3C13H8BrClFNO4
- [(2-Fluorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate437725-78-5C13H9BrFNO4
- [(3-Chloro-4-methoxyphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate386277-55-0C14H11BrClNO5
- [(2-Ethylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate1210746-45-4C15H14BrNO4
- [Ethyl(phenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate436117-67-8C15H14BrNO4
- [(2-Chloro-5-fluorophenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate1794798-79-0C13H8BrClFNO4
- [Methyl(3-methylphenyl)carbamoyl]methyl 5-bromofuran-2-carboxylate1794988-54-7C15H14BrNO4
Related scaffolds
Same ring framework with different atoms or bond orders
C(=CC1CCCC1)CCOc1ccccc137 chemicals
O=C(NCCCn1ccnc1)c1ccccc122 chemicals
O=S(=O)(NCCCn1ccnc1)c1ccccc120 chemicals
O=C(COC(=O)c1ccccc1)NC1CCCC117 chemicals
O=C(COc1ccccc1)NCC1CCCO117 chemicals
S=C(NCCc1ccccc1)Nc1nccs116 chemicals
O=C(CCS(=O)(=O)c1ccccc1)Nc1cccs113 chemicals![Scaffold O=C(CSc1ncn[nH]1)NCc1ccccc1](/scaffold/ZBSYLOJDGBMFAD-UHFFFAOYSA-N/structure.svg)
O=C(CSc1ncn[nH]1)NCc1ccccc113 chemicals
O=C(Cn1cccn1)NN=Cc1ccccc112 chemicals
O=C(NCC1CCCO1)C(=O)Nc1ccccc112 chemicals![Scaffold O=C(Cc1ccc[nH]1)NN=Cc1ccccc1](/scaffold/XCXHYNVYLRCCIP-UHFFFAOYSA-N/structure.svg)
O=C(Cc1ccc[nH]1)NN=Cc1ccccc112 chemicals![Scaffold O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n1](/scaffold/GFTUZBZNWRQYBL-UHFFFAOYSA-N/structure.svg)
O=C(NNC(=S)Nc1ccccc1)c1cc[nH]n111 chemicals