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Murcko scaffold

Ring system with 3 rings and 16 atoms

41 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
41
With full pages
4
Scaffold SMILES

c1ccc(Cn2ccc3cncnc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cn2ccc3cncnc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 41 of 41 chemicals

7-Benzyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine chemical structure, C13H12N4, CAS 14052-84-7
7-Benzyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS 14052-84-7C13H12N4
7-Benzyl-4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C15H14ClN3, CAS 173458-80-5
7-Benzyl-4-chloro-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidine
CAS 173458-80-5C15H14ClN3
7-Benzyl-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidin-4-amine chemical structure, C15H16N4, CAS 56344-53-7
7-Benzyl-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidin-4-amine
CAS 56344-53-7C15H16N4
2-[(7-Benzyl-5,6-dimethylpyrrolo[2,3-d]pyrimidin-4-yl)amino]ethanol chemical structure, C17H20N4O, CAS 903199-73-5
2-[(7-Benzyl-5,6-dimethylpyrrolo[2,3-d]pyrimidin-4-yl)amino]ethanol
CAS 903199-73-5C17H20N4O
7-(2-Fluorobenzyl)-4-chloro-7H-pyrrolo[2,3-D]pyrimidine chemical structure, C13H9ClFN3, CAS 171620-43-2
7-(2-Fluorobenzyl)-4-chloro-7H-pyrrolo[2,3-D]pyrimidine
CAS 171620-43-2C13H9ClFN3
7-Benzyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine chemical structure, C13H11ClN4, CAS 99044-54-9
7-Benzyl-4-chloro-7H-pyrrolo[2,3-d]pyrimidin-2-amine
CAS 99044-54-9C13H11ClN4
7-Benzyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile chemical structure, C14H10N4, CAS 480460-26-2
7-Benzyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS 480460-26-2C14H10N4
7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C14H12ClN3, CAS 26035-89-2
7-Benzyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
CAS 26035-89-2C14H12ClN3
5,6-Dimethyl-7-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine chemical structure, C16H19N5, CAS 111601-18-4
5,6-Dimethyl-7-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine
CAS 111601-18-4C16H19N5
4-Chloro-7-(phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C13H10ClN3, CAS 16019-34-4
4-Chloro-7-(phenylmethyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS 16019-34-4C13H10ClN3
7-Benzyl-4-chloro-6-ethyl-2-(methylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C16H16ClN3S, CAS 253332-25-1
7-Benzyl-4-chloro-6-ethyl-2-(methylsulfanyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS 253332-25-1C16H16ClN3S
7-Benzyl-2-methyl-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C14H13N3, CAS 803611-37-2
7-Benzyl-2-methyl-7H-pyrrolo[2,3-d]pyrimidine
CAS 803611-37-2C14H13N3
7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C13H9ClIN3, CAS 1244855-59-1
7-Benzyl-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
CAS 1244855-59-1C13H9ClIN3
N-[4-(4-Amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-ylmethyl)-phenyl]-methanesulfonamide chemical structure, C14H14IN5O2S, CAS 862729-14-4
N-[4-(4-Amino-5-iodo-pyrrolo[2,3-d]pyrimidin-7-ylmethyl)-phenyl]-methanesulfonamide
CAS 862729-14-4C14H14IN5O2S
7-Benzyl-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C13H9BrClN3, CAS 1244855-70-6
7-Benzyl-5-bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine
CAS 1244855-70-6C13H9BrClN3
7-(3-Fluorobenzyl)-4-chloro-7H-pyrrolo[2,3-D]pyrimidine chemical structure, C13H9ClFN3, CAS 1380310-97-3
7-(3-Fluorobenzyl)-4-chloro-7H-pyrrolo[2,3-D]pyrimidine
CAS 1380310-97-3C13H9ClFN3
7-(4-Fluorobenzyl)-4-chloro-7H-pyrrolo[2,3-D]pyrimidine chemical structure, C13H9ClFN3, CAS 1380310-99-5
7-(4-Fluorobenzyl)-4-chloro-7H-pyrrolo[2,3-D]pyrimidine
CAS 1380310-99-5C13H9ClFN3
7-Benzyl-4-chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C13H9ClFN3, CAS 1380310-83-7
7-Benzyl-4-chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine
CAS 1380310-83-7C13H9ClFN3
4-Chloro-7-(4-methoxybenzyl)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C15H14ClN3O, CAS 35808-74-3
4-Chloro-7-(4-methoxybenzyl)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
CAS 35808-74-3C15H14ClN3O
4-Chloro-7-(4-chlorobenzyl)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C14H11Cl2N3, CAS 35808-72-1
4-Chloro-7-(4-chlorobenzyl)-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
CAS 35808-72-1C14H11Cl2N3
7-Benzyl-4-chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C14H9ClF3N3, CAS 1365627-43-5
7-Benzyl-4-chloro-2-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS 1365627-43-5C14H9ClF3N3
2,4-Dichloro-7-(2-fluorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C13H8Cl2FN3, CAS 1075205-27-4
2,4-Dichloro-7-(2-fluorobenzyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS 1075205-27-4C13H8Cl2FN3
4-Chloro-7-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine chemical structure, C14H12ClN3, CAS 201003-65-8
4-Chloro-7-(1-phenylethyl)-7H-pyrrolo[2,3-d]pyrimidine
CAS 201003-65-8C14H12ClN3
Methyl 2-amino-4-chloro-7-(4-methoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate chemical structure, C16H15ClN4O3, CAS 1251760-86-7
Methyl 2-amino-4-chloro-7-(4-methoxybenzyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate
CAS 1251760-86-7C16H15ClN4O3