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Murcko scaffold

5,6-Dihydro-2H-pyran-2-one scaffold

204 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
204
With full pages
34
Scaffold SMILES

O=C1C=CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 5,6-Dihydro-2H-pyran-2-one page
Murcko scaffold O=C1C=CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 204 chemicals

6-Methyl-5,6-dihydro-2H-pyran-2-one chemical structure, C6H8O2, CAS 108-54-3
6-Methyl-5,6-dihydro-2H-pyran-2-one
CAS 108-54-3C6H8O2
6-Hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid chemical structure, C32H46O6
6-Hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid
C32H46O6
5-HYDROXY-2-DODECENOIC ACID delta-LACTONE chemical structure, C12H20O2, CAS 16400-72-9
5-HYDROXY-2-DODECENOIC ACID delta-LACTONE
CAS 16400-72-9C12H20O2
17-Ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-19-(3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid chemical structure, C33H48O7
17-Ethyl-6-hydroxy-9-(hydroxymethyl)-3,5,7,11,15-pentamethyl-19-(3-methyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid
C33H48O7
2H-Pyran-2-one, 6-butyl-5,6-dihydro- chemical structure, C9H14O2, CAS 16400-70-7
2H-Pyran-2-one, 6-butyl-5,6-dihydro-
CAS 16400-70-7C9H14O2
6-Allyl-5,6-dihydro-5-hydroxypyran-2-one chemical structure, C8H10O3, CAS 28921-94-0
6-Allyl-5,6-dihydro-5-hydroxypyran-2-one
CAS 28921-94-0C8H10O3
2H-Pyran-2-one, 5,6-dihydro-6,6-dimethyl-3-(1-methylethyl)- chemical structure, C10H16O2, CAS 97411-31-9
2H-Pyran-2-one, 5,6-dihydro-6,6-dimethyl-3-(1-methylethyl)-
CAS 97411-31-9C10H16O2
Gamahonolide A chemical structure, C12H20O3, CAS 125564-58-1
Gamahonolide A
CAS 125564-58-1C12H20O3
(2S)-2-((1S)-1-Hydroxypentyl)-4-methoxy-2,3-dihydropyran-6-one chemical structure, C11H18O4, CAS 34565-32-7
(2S)-2-((1S)-1-Hydroxypentyl)-4-methoxy-2,3-dihydropyran-6-one
CAS 34565-32-7C11H18O4
5,6-Dihydro-4-methoxy-6-methyl-2H-pyran-2-one chemical structure, C7H10O3, CAS 3791-79-5
5,6-Dihydro-4-methoxy-6-methyl-2H-pyran-2-one
CAS 3791-79-5C7H10O3
4,6,6-Trimethyl-5,6-dihydro-2H-pyran-2-one chemical structure, C8H12O2, CAS 6970-56-5
4,6,6-Trimethyl-5,6-dihydro-2H-pyran-2-one
CAS 6970-56-5C8H12O2
Diethyl 5-ethyl-6-oxo-2H-pyran-3,3(6H)-dicarboxylate chemical structure, C13H18O6, CAS 34993-71-0
Diethyl 5-ethyl-6-oxo-2H-pyran-3,3(6H)-dicarboxylate
CAS 34993-71-0C13H18O6
4-(Bromomethyl)-5,5-dimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile chemical structure, C9H10BrNO2, CAS 80946-00-5
4-(Bromomethyl)-5,5-dimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile
CAS 80946-00-5C9H10BrNO2
(S)-(+)-Massoialactone chemical structure, C10H16O2, CAS 61248-45-1
(S)-(+)-Massoialactone
CAS 61248-45-1C10H16O2
5,6-Dihydro-5,5-dimethyl-2-oxo-2H-pyran-3,4-dicarboxylic acid chemical structure, C9H10O6, CAS 60299-47-0
5,6-Dihydro-5,5-dimethyl-2-oxo-2H-pyran-3,4-dicarboxylic acid
CAS 60299-47-0C9H10O6
Pilosin A chemical structure, C26H48O6, CAS 69616-80-4
Pilosin A
CAS 69616-80-4C26H48O6
Parasorbic acid chemical structure, C6H8O2, CAS 10048-32-5
Parasorbic acid
CAS 10048-32-5C6H8O2
5,6-Dihydro-2H-pyran-2-one chemical structure, C5H6O2, CAS 3393-45-1
5,6-Dihydro-2H-pyran-2-one
CAS 3393-45-1C5H6O2
2,3-Anhydromevalonic acid chemical structure, C6H8O2, CAS 2381-87-5
2,3-Anhydromevalonic acid
CAS 2381-87-5C6H8O2
4,6,6-Trimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile chemical structure, C9H11NO2, CAS 69245-73-4
4,6,6-Trimethyl-2-oxo-5,6-dihydro-2H-pyran-3-carbonitrile
CAS 69245-73-4C9H11NO2
2H-Pyran-2-one, 4-(dimethylamino)-5,6-dihydro-5-methyl-6-pentyl- chemical structure, C13H23NO2, CAS 55045-06-2
2H-Pyran-2-one, 4-(dimethylamino)-5,6-dihydro-5-methyl-6-pentyl-
CAS 55045-06-2C13H23NO2
(R)-6-Ethyl-5,6-dihydro-2H-pyran-2-one chemical structure, C7H10O2, CAS 404958-09-4
(R)-6-Ethyl-5,6-dihydro-2H-pyran-2-one
CAS 404958-09-4C7H10O2
Massoia lactone chemical structure, C10H16O2, CAS 51154-96-2
Massoia lactone
CAS 51154-96-2C10H16O2
LL P880 beta chemical structure, C11H18O5, CAS 41164-59-4
LL P880 beta
CAS 41164-59-4C11H18O5