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Murcko scaffold

5,6-Dihydro-2H-pyran-2-one scaffold

204 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
204
With full pages
34
Scaffold SMILES

O=C1C=CCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 5,6-Dihydro-2H-pyran-2-one page
Murcko scaffold O=C1C=CCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 49 to 96 of 204 chemicals

Boronolide chemical structure, C18H26O8, CAS 33903-83-2
Boronolide
CAS 33903-83-2C18H26O8
(R)-5,6-Dihydro-4-methoxy-6-methyl-2H-pyran-2-one chemical structure, C7H10O3, CAS 221356-83-8
(R)-5,6-Dihydro-4-methoxy-6-methyl-2H-pyran-2-one
CAS 221356-83-8C7H10O3
4-Iodo-5,6-dihydro-2H-pyran-2-one chemical structure, C5H5IO2, CAS 214914-71-3
4-Iodo-5,6-dihydro-2H-pyran-2-one
CAS 214914-71-3C5H5IO2
3-Bromo-5,6-dihydro-2H-pyran-2-one chemical structure, C5H5BrO2, CAS 104184-64-7
3-Bromo-5,6-dihydro-2H-pyran-2-one
CAS 104184-64-7C5H5BrO2
(5S,6S)-5,6-Dihydro-5-(methoxymethoxy)-6-methyl-2H-pyran-2-one chemical structure, C8H12O4, CAS 205129-03-9
(5S,6S)-5,6-Dihydro-5-(methoxymethoxy)-6-methyl-2H-pyran-2-one
CAS 205129-03-9C8H12O4
3,5-Dibromo-5,6-dihydropyran-2-one chemical structure, C5H4Br2O2, CAS 137776-72-8
3,5-Dibromo-5,6-dihydropyran-2-one
CAS 137776-72-8C5H4Br2O2
[(2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]tetradeca-8,10,12-trien-5-yl] dihydrogen phosphate chemical structure, C21H33O7P, CAS 682329-63-1
[(2S,5S,6S,7S,8Z,10Z,12E)-7-Hydroxy-6-methyl-2-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]tetradeca-8,10,12-trien-5-yl] dihydrogen phosphate
CAS 682329-63-1C21H33O7P
5-Methyl-4-propan-2-yl-2,3-dihydropyran-6-one chemical structure, C9H14O2, CAS 162292-93-5
5-Methyl-4-propan-2-yl-2,3-dihydropyran-6-one
CAS 162292-93-5C9H14O2
Glkjzhblohozcb-gxsjlcmtsa- chemical structure, C12H14O8, CAS 22860-23-7
Glkjzhblohozcb-gxsjlcmtsa-
CAS 22860-23-7C12H14O8
2H-Pyran-2-one, 5-(acetyloxy)-5,6-dihydro-6-methyl-, (5R,6S)- chemical structure, C8H10O4, CAS 54621-88-4
2H-Pyran-2-one, 5-(acetyloxy)-5,6-dihydro-6-methyl-, (5R,6S)-
CAS 54621-88-4C8H10O4
2H-Pyran-2-one, 3-ethyl-5,6-dihydro- chemical structure, C7H10O2, CAS 85287-76-9
2H-Pyran-2-one, 3-ethyl-5,6-dihydro-
CAS 85287-76-9C7H10O2
Trichurusin J chemical structure, C27H40O7, CAS 867183-15-1
Trichurusin J
CAS 867183-15-1C27H40O7
Trichurusin G chemical structure, C25H36O7, CAS 867183-09-3
Trichurusin G
CAS 867183-09-3C25H36O7
(2S)-2-(Hydroxymethyl)-2,3-dihydropyran-6-one chemical structure, C6H8O3, CAS 89408-85-5
(2S)-2-(Hydroxymethyl)-2,3-dihydropyran-6-one
CAS 89408-85-5C6H8O3
Rasfonin chemical structure, C25H38O6, CAS 303156-68-5
Rasfonin
CAS 303156-68-5C25H38O6
Kazusamycin A chemical structure, C33H48O7, CAS 92090-94-3
Kazusamycin A
CAS 92090-94-3C33H48O7
Trichurusin F chemical structure, C25H36O7, CAS 867183-08-2
Trichurusin F
CAS 867183-08-2C25H36O7
Trichurusin K chemical structure, C27H40O7, CAS 867183-16-2
Trichurusin K
CAS 867183-16-2C27H40O7
(S)-6-Chloromethyl-5,6-dihydro-pyran-2-one chemical structure, C6H7ClO2, CAS 135999-61-0
(S)-6-Chloromethyl-5,6-dihydro-pyran-2-one
CAS 135999-61-0C6H7ClO2
Methyl (2s)-4-ethoxy-2-methyl-6-oxo-3,6-dihydro-2H-pyran-2-carboxylate chemical structure, C10H14O5, CAS 320603-99-4
Methyl (2s)-4-ethoxy-2-methyl-6-oxo-3,6-dihydro-2H-pyran-2-carboxylate
CAS 320603-99-4C10H14O5
2-Pentadecyl-2,3-dihydropyran-6-one chemical structure, C20H36O2, CAS 115124-57-7
2-Pentadecyl-2,3-dihydropyran-6-one
CAS 115124-57-7C20H36O2
Latrunculeic acid chemical structure, C17H24O4, CAS 721429-67-0
Latrunculeic acid
CAS 721429-67-0C17H24O4
(2R,3S)-2-Ethenyl-3-prop-2-enoxy-2,3-dihydropyran-6-one chemical structure, C10H12O3, CAS 634196-52-4
(2R,3S)-2-Ethenyl-3-prop-2-enoxy-2,3-dihydropyran-6-one
CAS 634196-52-4C10H12O3
2H-Pyran-2-one, 5-ethyl-5,6-dihydro- chemical structure, C7H10O2, CAS 88981-50-4
2H-Pyran-2-one, 5-ethyl-5,6-dihydro-
CAS 88981-50-4C7H10O2