CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 14 atoms

39 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
39
With full pages
4
Scaffold SMILES

O=C1Nc2ccccc2C12NN=CS2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1Nc2ccccc2C12NN=CS2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 39 of 39 chemicals

N-(4-Acetyl-5'-bromo-1'-ethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C15H15BrN4O3S, CAS 696603-08-4
N-(4-Acetyl-5'-bromo-1'-ethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 696603-08-4C15H15BrN4O3S
N-(1',4-Diacetyl-5'-chloro-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C15H13ClN4O4S, CAS 727999-48-6
N-(1',4-Diacetyl-5'-chloro-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 727999-48-6C15H13ClN4O4S
N-(4-Acetyl-5'-methoxy-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C17H20N4O4S, CAS 824980-28-1
N-(4-Acetyl-5'-methoxy-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 824980-28-1C17H20N4O4S
N-{3'-Acetyl-1-[2-(diethylamino)ethyl]-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-5'-yl}acetamide chemical structure, C19H25N5O3S, CAS 727999-45-3
N-{3'-Acetyl-1-[2-(diethylamino)ethyl]-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-5'-yl}acetamide
CAS 727999-45-3C19H25N5O3S
N-(4-Acetyl-5'-bromo-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C16H17BrN4O3S, CAS 825655-89-8
N-(4-Acetyl-5'-bromo-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 825655-89-8C16H17BrN4O3S
N-(4-Acetyl-4'-chloro-1',7'-dimethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C15H15ClN4O3S, CAS 838881-57-5
N-(4-Acetyl-4'-chloro-1',7'-dimethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 838881-57-5C15H15ClN4O3S
N-(4-Acetyl-5'-methyl-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C17H20N4O3S, CAS 585550-60-3
N-(4-Acetyl-5'-methyl-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 585550-60-3C17H20N4O3S
N-(4-Acetyl-5'-methyl-2'-oxo-1'-propan-2-ylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C17H20N4O3S, CAS 578760-10-8
N-(4-Acetyl-5'-methyl-2'-oxo-1'-propan-2-ylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 578760-10-8C17H20N4O3S
N-(1',4-Diacetyl-5'-ethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C17H18N4O4S, CAS 799263-54-0
N-(1',4-Diacetyl-5'-ethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 799263-54-0C17H18N4O4S
N-(4-Acetyl-5'-ethyl-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C18H22N4O3S, CAS 843619-83-0
N-(4-Acetyl-5'-ethyl-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 843619-83-0C18H22N4O3S
N-(4-Acetyl-5'-ethyl-2'-oxo-1'-propan-2-ylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C18H22N4O3S, CAS 585560-52-7
N-(4-Acetyl-5'-ethyl-2'-oxo-1'-propan-2-ylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 585560-52-7C18H22N4O3S
N-(4-Acetyl-1',5',7'-trimethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C16H18N4O3S, CAS 799263-57-3
N-(4-Acetyl-1',5',7'-trimethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 799263-57-3C16H18N4O3S
N-(4-Acetyl-1'-ethyl-5',7'-dimethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C17H20N4O3S, CAS 579443-08-6
N-(4-Acetyl-1'-ethyl-5',7'-dimethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 579443-08-6C17H20N4O3S
N-(4-Acetyl-1'-ethyl-5'-methoxy-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C16H18N4O4S, CAS 577998-82-4
N-(4-Acetyl-1'-ethyl-5'-methoxy-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 577998-82-4C16H18N4O4S
N-(4-Acetyl-5'-ethoxy-1'-ethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C17H20N4O4S, CAS 578750-39-7
N-(4-Acetyl-5'-ethoxy-1'-ethyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 578750-39-7C17H20N4O4S
N-[4-Acetyl-1'-[2-(diethylamino)ethyl]-5'-methyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl]acetamide chemical structure, C20H27N5O3S, CAS 727999-46-4
N-[4-Acetyl-1'-[2-(diethylamino)ethyl]-5'-methyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl]acetamide
CAS 727999-46-4C20H27N5O3S
N-[3-Acetyl-6-(2-methylpropyl)-7-oxospiro[1,3,4-thiadiazoline-2,3'-indoline]-5-yl]acetamide chemical structure, C17H20N4O3S, CAS 843632-78-0
N-[3-Acetyl-6-(2-methylpropyl)-7-oxospiro[1,3,4-thiadiazoline-2,3'-indoline]-5-yl]acetamide
CAS 843632-78-0C17H20N4O3S
N-(3'-Acetyl-1-butyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-5'-yl)acetamide chemical structure, C17H20N4O3S, CAS 578743-39-2
N-(3'-Acetyl-1-butyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-5'-yl)acetamide
CAS 578743-39-2C17H20N4O3S
N-(4-Acetyl-5'-fluoro-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C16H17FN4O3S, CAS 840486-23-9
N-(4-Acetyl-5'-fluoro-2'-oxo-1'-propylspiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 840486-23-9C16H17FN4O3S
N-(4-Acetyl-1'-butyl-5'-methyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide chemical structure, C18H22N4O3S, CAS 842970-59-6
N-(4-Acetyl-1'-butyl-5'-methyl-2'-oxospiro[1,3,4-thiadiazole-5,3'-indole]-2-yl)acetamide
CAS 842970-59-6C18H22N4O3S
N-(3-Acetyl-7-oxo-6-prop-2-enylspiro[1,3,4-thiadiazoline-2,3'-indoline]-5-yl)a cetamide chemical structure, C16H16N4O3S, CAS 902255-00-9
N-(3-Acetyl-7-oxo-6-prop-2-enylspiro[1,3,4-thiadiazoline-2,3'-indoline]-5-yl)a cetamide
CAS 902255-00-9C16H16N4O3S
N-(3'-Acetyl-1-ethyl-7-methyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-5'-yl)acetamide chemical structure, C16H18N4O3S, CAS 902248-24-2
N-(3'-Acetyl-1-ethyl-7-methyl-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazol]-5'-yl)acetamide
CAS 902248-24-2C16H18N4O3S
N-(3'-Acetyl-1-allyl-5-bromo-2-oxo-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-5'-yl)acetamide chemical structure, C16H15BrN4O3S, CAS 902248-51-5
N-(3'-Acetyl-1-allyl-5-bromo-2-oxo-3'H-spiro[indoline-3,2'-[1,3,4]thiadiazol]-5'-yl)acetamide
CAS 902248-51-5C16H15BrN4O3S
N-[3'-Acetyl-5-bromo-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazole]-5'-yl]acetamide chemical structure, C17H19BrN4O3S, CAS 902248-53-7
N-[3'-Acetyl-5-bromo-1-(2-methylpropyl)-2-oxo-1,2-dihydro-3'H-spiro[indole-3,2'-[1,3,4]thiadiazole]-5'-yl]acetamide
CAS 902248-53-7C17H19BrN4O3S