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Murcko scaffold

2,3-Dihydrospiro(indene-1,3'-pyrrolidine) scaffold

20 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
20
With full pages
2
Scaffold SMILES

c1ccc2c(c1)CCC21CCNC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3-Dihydrospiro(indene-1,3'-pyrrolidine) page
Murcko scaffold c1ccc2c(c1)CCC21CCNC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

2,3-Dihydrospiro(indene-1,3'-pyrrolidine) chemical structure, C12H15N, CAS 16976-98-0
2,3-Dihydrospiro(indene-1,3'-pyrrolidine)
CAS 16976-98-0C12H15N
2,3-Dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride chemical structure, C12H16ClN, CAS 81962-05-2
2,3-Dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride
CAS 81962-05-2C12H16ClN
Spiro[indan-1,3'-pyrrolidin]-3-ol chemical structure, C12H15NO, CAS 40877-22-3
Spiro[indan-1,3'-pyrrolidin]-3-ol
CAS 40877-22-3C12H15NO
2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-5,6-diol chemical structure, C12H15NO2, CAS 100038-04-8
2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-5,6-diol
CAS 100038-04-8C12H15NO2
2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-4,5-diol chemical structure, C12H15NO2, CAS 100038-00-4
2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-4,5-diol
CAS 100038-00-4C12H15NO2
7-Bromospiro[1,2-dihydroindene-3,3'-pyrrolidine] chemical structure, C12H14BrN, CAS 956142-11-3
7-Bromospiro[1,2-dihydroindene-3,3'-pyrrolidine]
CAS 956142-11-3C12H14BrN
6-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine] chemical structure, C12H14BrN, CAS 956142-10-2
6-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]
CAS 956142-10-2C12H14BrN
5-Fluoro-2,3-dihydrospiro[indene-1,3'-pyrrolidine] chemical structure, C12H14FN, CAS 956142-27-1
5-Fluoro-2,3-dihydrospiro[indene-1,3'-pyrrolidine]
CAS 956142-27-1C12H14FN
5-Chloro-2,3-dihydrospiro[indene-1,3'-pyrrolidine] chemical structure, C12H14ClN, CAS 956141-91-6
5-Chloro-2,3-dihydrospiro[indene-1,3'-pyrrolidine]
CAS 956141-91-6C12H14ClN
5-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine] chemical structure, C12H14BrN, CAS 956141-86-9
5-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]
CAS 956141-86-9C12H14BrN
5-Chloro-2,3-dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride chemical structure, C12H15Cl2N, CAS 956141-93-8
5-Chloro-2,3-dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride
CAS 956141-93-8C12H15Cl2N
1'-Methyl-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-4,5-diol chemical structure, C13H17NO2, CAS 100038-02-6
1'-Methyl-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-4,5-diol
CAS 100038-02-6C13H17NO2
1'-Methyl-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-5,6-diol chemical structure, C13H17NO2, CAS 100038-06-0
1'-Methyl-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-5,6-diol
CAS 100038-06-0C13H17NO2
Ethyl 2,3-dihydrospiro[indene-1,3'-pyrrolidine]-4'-carboxylate chemical structure, C15H19NO2, CAS 1772254-14-4
Ethyl 2,3-dihydrospiro[indene-1,3'-pyrrolidine]-4'-carboxylate
CAS 1772254-14-4C15H19NO2
Spiro[1H-indene-1,3'-pyrrolidine]-1'-carboxylic acid, 4-bromo-2,3-dihydro-, 1,1-dimethylethyl ester chemical structure, C17H22BrNO2, CAS 2243420-80-4
Spiro[1H-indene-1,3'-pyrrolidine]-1'-carboxylic acid, 4-bromo-2,3-dihydro-, 1,1-dimethylethyl ester
CAS 2243420-80-4C17H22BrNO2
2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-1'-carboxamide chemical structure, C13H16N2O, CAS 2408958-09-6
2,3-Dihydrospiro[indene-1,3'-pyrrolidine]-1'-carboxamide
CAS 2408958-09-6C13H16N2O
6-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride chemical structure, C12H15BrClN, CAS 2490420-70-5
6-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride
CAS 2490420-70-5C12H15BrClN
5-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride chemical structure, C12H15BrClN, CAS 2551116-78-8
5-Bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine] hydrochloride
CAS 2551116-78-8C12H15BrClN
tert-Butyl 6-bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-1'-carboxylate chemical structure, C17H22BrNO2, CAS 2680694-87-3
tert-Butyl 6-bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-1'-carboxylate
CAS 2680694-87-3C17H22BrNO2
tert-Butyl 5-bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-1'-carboxylate chemical structure, C17H22BrNO2, CAS 2680882-43-1
tert-Butyl 5-bromo-2,3-dihydrospiro[indene-1,3'-pyrrolidine]-1'-carboxylate
CAS 2680882-43-1C17H22BrNO2