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Murcko scaffold

Ring system with 3 rings and 14 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
11
With full pages
1
Scaffold SMILES

O=c1cccc2n1CCC21OCCO1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cccc2n1CCC21OCCO1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate chemical structure, C17H20N2O5, CAS 58610-66-5
Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate
CAS 58610-66-5C17H20N2O5
Ethyl 6'-cyano-2',3'-dihydro-5'-oxospiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetate chemical structure, C15H16N2O5, CAS 58610-65-4
Ethyl 6'-cyano-2',3'-dihydro-5'-oxospiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetate
CAS 58610-65-4C15H16N2O5
Agn-PC-0K1Y3B chemical structure, C12H12N2O3, CAS 58610-64-3
Agn-PC-0K1Y3B
CAS 58610-64-3C12H12N2O3
Ethyl 2-(6-(acetoxymethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate chemical structure, C19H25NO7, CAS 73427-97-1
Ethyl 2-(6-(acetoxymethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate
CAS 73427-97-1C19H25NO7
Ethyl bromo(6'-cyano-5'-oxo-2',3'-dihydro-5'H-spiro[[1,3]dioxolane-2,1'-indolizin]-7'-yl)acetate chemical structure, C15H15BrN2O5, CAS 110714-43-7
Ethyl bromo(6'-cyano-5'-oxo-2',3'-dihydro-5'H-spiro[[1,3]dioxolane-2,1'-indolizin]-7'-yl)acetate
CAS 110714-43-7C15H15BrN2O5
Ethyl 2-(6-(acetamidomethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate chemical structure, C19H26N2O6, CAS 127452-30-6
Ethyl 2-(6-(acetamidomethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate
CAS 127452-30-6C19H26N2O6
Ethyl 2-(6-formyl-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate chemical structure, C17H21NO6, CAS 1010803-94-7
Ethyl 2-(6-formyl-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)butanoate
CAS 1010803-94-7C17H21NO6
Ethyl 6a(2)-[(acetylnitrosoamino)methyl]-I+/--ethyl-2a(2),3a(2)-dihydro-5a(2)-oxospiro[1,3-dioxolane-2,1a(2)(5a(2)H)-indolizine]-7a(2)-acetate chemical structure, C19H25N3O7, CAS 73427-98-2
Ethyl 6a(2)-[(acetylnitrosoamino)methyl]-I+/--ethyl-2a(2),3a(2)-dihydro-5a(2)-oxospiro[1,3-dioxolane-2,1a(2)(5a(2)H)-indolizine]-7a(2)-acetate
CAS 73427-98-2C19H25N3O7
Ethyl 2-(6-(acetamidomethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)propanoate chemical structure, C18H24N2O6, CAS 1586782-22-0
Ethyl 2-(6-(acetamidomethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)propanoate
CAS 1586782-22-0C18H24N2O6
Ethyl 2-(6-(acetoxymethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)propanoate chemical structure, C18H23NO7, CAS 1586782-25-3
Ethyl 2-(6-(acetoxymethyl)-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)propanoate
CAS 1586782-25-3C18H23NO7
Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)propanoate chemical structure, C16H18N2O5, CAS 1586782-19-5
Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)propanoate
CAS 1586782-19-5C16H18N2O5