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Murcko scaffold

1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-phenyl- scaffold

71 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
71
With full pages
6
Scaffold SMILES

O=C1C2=C(CCCC2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-phenyl- page
Murcko scaffold O=C1C2=C(CCCC2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 71 chemicals

Benzoic acid, 4-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)- chemical structure, C15H13NO4, CAS 39985-88-1
Benzoic acid, 4-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-
CAS 39985-88-1C15H13NO4
Benzamide, N,N-diethyl-4-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)- chemical structure, C19H22N2O3, CAS 61356-10-3
Benzamide, N,N-diethyl-4-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-
CAS 61356-10-3C19H22N2O3
2-(Diethylamino)ethyl 4-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)benzoate--hydrogen chloride (1/1) chemical structure, C21H27ClN2O4, CAS 61356-11-4
2-(Diethylamino)ethyl 4-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)benzoate--hydrogen chloride (1/1)
CAS 61356-11-4C21H27ClN2O4
Benzoic acid, 3-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-, 2-(diethylamino)ethyl ester, monohydrochloride chemical structure, C21H27ClN2O4, CAS 61356-12-5
Benzoic acid, 3-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-, 2-(diethylamino)ethyl ester, monohydrochloride
CAS 61356-12-5C21H27ClN2O4
Flumiclorac chemical structure, C16H13ClFNO5, CAS 87547-04-4
Flumiclorac
CAS 87547-04-4C16H13ClFNO5
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-(2-propynyloxy)phenyl)-4,5,6,7-tetrahydro- chemical structure, C17H13ClFNO3, CAS 84478-42-2
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-(2-propynyloxy)phenyl)-4,5,6,7-tetrahydro-
CAS 84478-42-2C17H13ClFNO3
Chlorphthalim chemical structure, C14H12ClNO2, CAS 39985-63-2
Chlorphthalim
CAS 39985-63-2C14H12ClNO2
Propan-2-yl 2-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-4-fluorobenzoate chemical structure, C18H17ClFNO4, CAS 81663-36-7
Propan-2-yl 2-chloro-5-(1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl)-4-fluorobenzoate
CAS 81663-36-7C18H17ClFNO4
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-3-(2-propynyloxy)phenyl)-4,5,6,7-tetrahydro- chemical structure, C17H14ClNO3, CAS 76464-03-4
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-3-(2-propynyloxy)phenyl)-4,5,6,7-tetrahydro-
CAS 76464-03-4C17H14ClNO3
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(3-methoxyphenyl)- chemical structure, C15H15NO3, CAS 76995-54-5
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(3-methoxyphenyl)-
CAS 76995-54-5C15H15NO3
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(4-(trifluoromethyl)phenyl)- chemical structure, C15H12F3NO2, CAS 76995-55-6
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(4-(trifluoromethyl)phenyl)-
CAS 76995-55-6C15H12F3NO2
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(4-methoxy-3-methylphenyl)- chemical structure, C16H17NO3, CAS 76995-58-9
1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrahydro-2-(4-methoxy-3-methylphenyl)-
CAS 76995-58-9C16H17NO3
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-3-nitrophenyl)-4,5,6,7-tetrahydro- chemical structure, C14H11ClN2O4, CAS 76995-59-0
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-3-nitrophenyl)-4,5,6,7-tetrahydro-
CAS 76995-59-0C14H11ClN2O4
Flumipropyn chemical structure, C18H15ClFNO3, CAS 84478-52-4
Flumipropyn
CAS 84478-52-4C18H15ClFNO3
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-(1-methylethoxy)phenyl)-4,5,6,7-tetrahydro- chemical structure, C17H17ClFNO3, CAS 84478-39-7
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-(1-methylethoxy)phenyl)-4,5,6,7-tetrahydro-
CAS 84478-39-7C17H17ClFNO3
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-hydroxyphenyl)-4,5,6,7-tetrahydro- chemical structure, C14H11ClFNO3, CAS 84478-41-1
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-hydroxyphenyl)-4,5,6,7-tetrahydro-
CAS 84478-41-1C14H11ClFNO3
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro- chemical structure, C15H13ClFNO3, CAS 84478-44-4
1H-Isoindole-1,3(2H)-dione, 2-(4-chloro-2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro-
CAS 84478-44-4C15H13ClFNO3
1H-Isoindole-1,3(2H)-dione, 2-(4-bromo-2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro- chemical structure, C15H13BrFNO3, CAS 84478-57-9
1H-Isoindole-1,3(2H)-dione, 2-(4-bromo-2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro-
CAS 84478-57-9C15H13BrFNO3
1H-Isoindole-1,3(2H)-dione, 2-(2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro- chemical structure, C15H14FNO3, CAS 134882-48-7
1H-Isoindole-1,3(2H)-dione, 2-(2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro-
CAS 134882-48-7C15H14FNO3
1H-Isoindole-1,3(2H)-dione, 2-(2-fluoro-5-methoxy-4-(methylthio)phenyl)-4,5,6,7-tetrahydro- chemical structure, C16H16FNO3S, CAS 134882-49-8
1H-Isoindole-1,3(2H)-dione, 2-(2-fluoro-5-methoxy-4-(methylthio)phenyl)-4,5,6,7-tetrahydro-
CAS 134882-49-8C16H16FNO3S
1H-Isoindole-1,3(2H)-dione, 2-(2-fluoro-5-methoxy-4-nitrophenyl)-4,5,6,7-tetrahydro- chemical structure, C15H13FN2O5, CAS 134882-50-1
1H-Isoindole-1,3(2H)-dione, 2-(2-fluoro-5-methoxy-4-nitrophenyl)-4,5,6,7-tetrahydro-
CAS 134882-50-1C15H13FN2O5
1H-Isoindole-1,3(2H)-dione, 2-(4-amino-2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro- chemical structure, C15H15FN2O3, CAS 134882-51-2
1H-Isoindole-1,3(2H)-dione, 2-(4-amino-2-fluoro-5-methoxyphenyl)-4,5,6,7-tetrahydro-
CAS 134882-51-2C15H15FN2O3
Acetamide, N-(5-fluoro-4-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxyphenyl)- chemical structure, C17H17FN2O4, CAS 134882-52-3
Acetamide, N-(5-fluoro-4-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxyphenyl)-
CAS 134882-52-3C17H17FN2O4
Methanesulfonamide, N-(5-fluoro-4-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxyphenyl)- chemical structure, C16H17FN2O5S, CAS 134882-53-4
Methanesulfonamide, N-(5-fluoro-4-(1,3,4,5,6,7-hexahydro-1,3-dioxo-2H-isoindol-2-yl)-2-methoxyphenyl)-
CAS 134882-53-4C16H17FN2O5S