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Murcko scaffold

Ring system with 3 rings and 18 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
15
With full pages
5
Scaffold SMILES

c1cc(N2CCCCC2)cc(N2CCNCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cc(N2CCCCC2)cc(N2CCNCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

1-Methylsulfonyl-4-(4-nitro-3-piperidin-1-ylphenyl)piperazine chemical structure, C16H24N4O4S, CAS 346704-11-8
1-Methylsulfonyl-4-(4-nitro-3-piperidin-1-ylphenyl)piperazine
CAS 346704-11-8C16H24N4O4S
1-(4-Nitro-3-piperidin-1-ylphenyl)piperazine chemical structure, C15H22N4O2, CAS 346704-04-9
1-(4-Nitro-3-piperidin-1-ylphenyl)piperazine
CAS 346704-04-9C15H22N4O2
3-Methyl-1-(4-nitro-3-piperidin-1-ylphenyl)piperazine chemical structure, C16H24N4O2, CAS 330634-17-8
3-Methyl-1-(4-nitro-3-piperidin-1-ylphenyl)piperazine
CAS 330634-17-8C16H24N4O2
1-Methyl-4-(4-nitro-3-(piperidin-1-yl)phenyl)piperazine chemical structure, C16H24N4O2, CAS 353501-02-7
1-Methyl-4-(4-nitro-3-(piperidin-1-yl)phenyl)piperazine
CAS 353501-02-7C16H24N4O2
1-[4-(4-Nitro-3-piperidin-1-ylphenyl)piperazin-1-yl]ethanone chemical structure, C17H24N4O3, CAS 347356-38-1
1-[4-(4-Nitro-3-piperidin-1-ylphenyl)piperazin-1-yl]ethanone
CAS 347356-38-1C17H24N4O3
1-Ethylsulfonyl-4-(4-nitro-3-piperidin-1-ylphenyl)piperazine chemical structure, C17H26N4O4S, CAS 593238-13-2
1-Ethylsulfonyl-4-(4-nitro-3-piperidin-1-ylphenyl)piperazine
CAS 593238-13-2C17H26N4O4S
2,2-Dimethyl-1-[4-(4-nitro-3-piperidin-1-ylphenyl)piperazin-1-yl]propan-1-one chemical structure, C20H30N4O3, CAS 662164-19-4
2,2-Dimethyl-1-[4-(4-nitro-3-piperidin-1-ylphenyl)piperazin-1-yl]propan-1-one
CAS 662164-19-4C20H30N4O3
1-(4-[4-Fluoro-5-(4-methylpiperidin-1-yl)-2-nitrophenyl]piperazin-1-yl)ethan-1-one chemical structure, C18H25FN4O3, CAS 403735-81-9
1-(4-[4-Fluoro-5-(4-methylpiperidin-1-yl)-2-nitrophenyl]piperazin-1-yl)ethan-1-one
CAS 403735-81-9C18H25FN4O3
4-(4-Methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)aniline chemical structure, C17H28N4, CAS 1160474-88-3
4-(4-Methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)aniline
CAS 1160474-88-3C17H28N4
4-(4-Methylpiperazin-1-yl)-2-(piperidin-1-yl)aniline chemical structure, C16H26N4, CAS 885704-69-8
4-(4-Methylpiperazin-1-yl)-2-(piperidin-1-yl)aniline
CAS 885704-69-8C16H26N4
(1-(2-Amino-5-(4-methylpiperazin-1-yl)phenyl)piperidin-4-yl)methanol chemical structure, C17H28N4O, CAS 2247849-75-6
(1-(2-Amino-5-(4-methylpiperazin-1-yl)phenyl)piperidin-4-yl)methanol
CAS 2247849-75-6C17H28N4O
tert-Butyl 4-[4-nitro-3-(piperidin-1-yl)phenyl]piperazine-1-carboxylate chemical structure, C20H30N4O4, CAS 2354364-35-3
tert-Butyl 4-[4-nitro-3-(piperidin-1-yl)phenyl]piperazine-1-carboxylate
CAS 2354364-35-3C20H30N4O4
tert-Butyl 4-(4-amino-3-(piperidin-1-yl)phenyl)piperazine-1-carboxylate chemical structure, C20H32N4O2, CAS 2326571-32-6
tert-Butyl 4-(4-amino-3-(piperidin-1-yl)phenyl)piperazine-1-carboxylate
CAS 2326571-32-6C20H32N4O2
2-(4-Methylpiperazin-1-yl)-4-(piperidin-1-yl)aniline chemical structure, C16H26N4, CAS 2411636-31-0
2-(4-Methylpiperazin-1-yl)-4-(piperidin-1-yl)aniline
CAS 2411636-31-0C16H26N4
1-(4-Amino-3-(4-methylpiperazin-1-yl)phenyl)piperidin-4-ol chemical structure, C16H26N4O, CAS 2411635-20-4
1-(4-Amino-3-(4-methylpiperazin-1-yl)phenyl)piperidin-4-ol
CAS 2411635-20-4C16H26N4O