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Murcko scaffold

3-(Pyrrolidin-2-ylmethyl)-1H-indole scaffold

29 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
29
With full pages
3
Scaffold SMILES

c1ccc2c(CC3CCCN3)c[nH]c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(Pyrrolidin-2-ylmethyl)-1H-indole page
Murcko scaffold c1ccc2c(CC3CCCN3)c[nH]c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

N-Methyl-3-(((2R)-1-methyl-2-pyrrolidinyl)methyl)-1H-indole-5-methanesulfonamide chemical structure, C16H23N3O2S, CAS 143321-74-8
N-Methyl-3-(((2R)-1-methyl-2-pyrrolidinyl)methyl)-1H-indole-5-methanesulfonamide
CAS 143321-74-8C16H23N3O2S
CP 122638 chemical structure, C15H21N3O2S, CAS 143321-78-2
CP 122638
CAS 143321-78-2C15H21N3O2S
5-MeO-MPMI chemical structure, C15H20N2O, CAS 143321-57-7
5-MeO-MPMI
CAS 143321-57-7C15H20N2O
5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole chemical structure, C16H22N2, CAS 209682-64-4
5-Ethyl-3-[[(2R)-1-methyl-2-pyrrolidinyl]methyl]-1H-indole
CAS 209682-64-4C16H22N2
(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole chemical structure, C16H20N2, CAS 209682-80-4
(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-5-vinyl-1H-indole
CAS 209682-80-4C16H20N2
Lucigenol chemical structure, C14H18N2O, CAS 250672-65-2
Lucigenol
CAS 250672-65-2C14H18N2O
(R)-5-Bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole chemical structure, C14H17BrN2, CAS 143322-57-0
(R)-5-Bromo-3-(1-methyl-2-pyrrolidinyl methyl)-1H-indole
CAS 143322-57-0C14H17BrN2
Pyrrolidine, 2-[(1-acetyl-1H-indol-3-yl)methyl]-1-(L-alanyl-L-valyl)-, (2S)- chemical structure, C23H32N4O3, CAS 874774-46-6
Pyrrolidine, 2-[(1-acetyl-1H-indol-3-yl)methyl]-1-(L-alanyl-L-valyl)-, (2S)-
CAS 874774-46-6C23H32N4O3
(R)-1-(5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indol-1-yl)ethanone chemical structure, C16H19BrN2O, CAS 205369-12-6
(R)-1-(5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indol-1-yl)ethanone
CAS 205369-12-6C16H19BrN2O
5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole chemical structure, C14H17BrN2, CAS 312949-16-9
5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
CAS 312949-16-9C14H17BrN2
3-(Pyrrolidin-2-ylmethyl)-1H-indole chemical structure, C13H16N2, CAS 143321-77-1
3-(Pyrrolidin-2-ylmethyl)-1H-indole
CAS 143321-77-1C13H16N2
5-Bromo-1-(t-butyloxycarbonyl)-3-(1-methylpyrrolidin-2(R)-ylmethyl)-indole chemical structure, C19H25BrN2O2, CAS 153435-65-5
5-Bromo-1-(t-butyloxycarbonyl)-3-(1-methylpyrrolidin-2(R)-ylmethyl)-indole
CAS 153435-65-5C19H25BrN2O2
1H-Indole, 5-bromo-3-(2-pyrrolidinylmethyl)-, (R)- chemical structure, C13H15BrN2, CAS 153435-71-3
1H-Indole, 5-bromo-3-(2-pyrrolidinylmethyl)-, (R)-
CAS 153435-71-3C13H15BrN2
(S)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole chemical structure, C14H17BrN2, CAS 208464-41-9
(S)-5-Bromo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indole
CAS 208464-41-9C14H17BrN2
(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-1H-indole chemical structure, C14H18N2, CAS 143322-55-8
(R)-3-((1-Methylpyrrolidin-2-yl)methyl)-1H-indole
CAS 143322-55-8C14H18N2
1H-Indole-5-carbonitrile, 3-(2-pyrrolidinylmethyl)-, (R)- chemical structure, C14H15N3, CAS 143322-67-2
1H-Indole-5-carbonitrile, 3-(2-pyrrolidinylmethyl)-, (R)-
CAS 143322-67-2C14H15N3
(R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl-d5)-1H-indole chemical structure, C14H17BrN2, CAS 1126745-77-4
(R)-5-Bromo-3-(N-methylpyrrolidin-2-ylmethyl-d5)-1H-indole
CAS 1126745-77-4C14H17BrN2
6-Chloro-3-[(pyrrolidin-2-yl)methyl]-1H-indole chemical structure, C13H15ClN2, CAS 1500905-30-5
6-Chloro-3-[(pyrrolidin-2-yl)methyl]-1H-indole
CAS 1500905-30-5C13H15ClN2
(S)-tert-Butyl 2-((6-fluoro-1H-indol-3-yl)methyl)pyrrolidine-1-carboxylate chemical structure, C18H23FN2O2, CAS 874774-56-8
(S)-tert-Butyl 2-((6-fluoro-1H-indol-3-yl)methyl)pyrrolidine-1-carboxylate
CAS 874774-56-8C18H23FN2O2
3-Pyrrolidin-2-ylmethyl-indole-1-carboxylic acid tert-butyl ester chemical structure, C18H24N2O2, CAS 886370-63-4
3-Pyrrolidin-2-ylmethyl-indole-1-carboxylic acid tert-butyl ester
CAS 886370-63-4C18H24N2O2
5-Methoxy-2-methyl-3-(pyrrolidin-2-ylmethyl)-1H-indole chemical structure, C15H20N2O, CAS 1706432-08-7
5-Methoxy-2-methyl-3-(pyrrolidin-2-ylmethyl)-1H-indole
CAS 1706432-08-7C15H20N2O
(R)-1-(5-BroMo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indol-1-yl)ethanone (Hydrochloride) chemical structure, C16H20BrClN2O, CAS 1415566-35-6
(R)-1-(5-BroMo-3-((1-methylpyrrolidin-2-yl)methyl)-1H-indol-1-yl)ethanone (Hydrochloride)
CAS 1415566-35-6C16H20BrClN2O
1-Methyl-3-[(pyrrolidin-2-yl)methyl]-1H-indole chemical structure, C14H18N2, CAS 1369068-60-9
1-Methyl-3-[(pyrrolidin-2-yl)methyl]-1H-indole
CAS 1369068-60-9C14H18N2
1,2-Dimethyl-3-[(pyrrolidin-2-yl)methyl]-1H-indole chemical structure, C15H20N2, CAS 1368920-35-7
1,2-Dimethyl-3-[(pyrrolidin-2-yl)methyl]-1H-indole
CAS 1368920-35-7C15H20N2