CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 20 atoms

114 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
20
Chemicals
114
With full pages
19
Scaffold SMILES

O=C(CCS(=O)(=O)c1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCS(=O)(=O)c1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 114 chemicals

Bicalutamide chemical structure, C18H14F4N2O4S, CAS 90357-06-5
Bicalutamide
CAS 90357-06-5C18H14F4N2O4S
(R)-Bicalutamide chemical structure, C18H14F4N2O4S, CAS 113299-40-4
(R)-Bicalutamide
CAS 113299-40-4C18H14F4N2O4S
(S)-Bicalutamide chemical structure, C18H14F4N2O4S, CAS 113299-38-0
(S)-Bicalutamide
CAS 113299-38-0C18H14F4N2O4S
N-(3-Chlorophenyl)-3-(4-methylphenyl)sulfonylpropanamide chemical structure, C16H16ClNO3S, CAS 428851-18-7
N-(3-Chlorophenyl)-3-(4-methylphenyl)sulfonylpropanamide
CAS 428851-18-7C16H16ClNO3S
N-(2-Methoxyphenyl)-3-(phenylsulfonyl)propanamide chemical structure, C16H17NO4S, CAS 452062-13-4
N-(2-Methoxyphenyl)-3-(phenylsulfonyl)propanamide
CAS 452062-13-4C16H17NO4S
N-(2,4-Difluorophenyl)-3-(4-methylbenzenesulfonyl)propanamide chemical structure, C16H15F2NO3S, CAS 697257-27-5
N-(2,4-Difluorophenyl)-3-(4-methylbenzenesulfonyl)propanamide
CAS 697257-27-5C16H15F2NO3S
N-(4-Chlorophenyl)-3-[(4-methylphenyl)sulfonyl]propanamide chemical structure, C16H16ClNO3S, CAS 442530-82-7
N-(4-Chlorophenyl)-3-[(4-methylphenyl)sulfonyl]propanamide
CAS 442530-82-7C16H16ClNO3S
N-(4-Fluorophenyl)-3-[(4-methylphenyl)sulfonyl]propanamide chemical structure, C16H16FNO3S, CAS 694515-09-8
N-(4-Fluorophenyl)-3-[(4-methylphenyl)sulfonyl]propanamide
CAS 694515-09-8C16H16FNO3S
N-(4-Bromophenyl)-3-[(4-methylphenyl)sulfonyl]propanamide chemical structure, C16H16BrNO3S, CAS 694485-75-1
N-(4-Bromophenyl)-3-[(4-methylphenyl)sulfonyl]propanamide
CAS 694485-75-1C16H16BrNO3S
3-(4-Chlorophenyl)sulfonyl-N-(4-methoxyphenyl)propanamide chemical structure, C16H16ClNO4S, CAS 683807-47-8
3-(4-Chlorophenyl)sulfonyl-N-(4-methoxyphenyl)propanamide
CAS 683807-47-8C16H16ClNO4S
N-(4-Chlorophenyl)-3-[(4-chlorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide chemical structure, C16H15Cl2NO4S, CAS 339275-83-1
N-(4-Chlorophenyl)-3-[(4-chlorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
CAS 339275-83-1C16H15Cl2NO4S
3-[(4-Chlorophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide chemical structure, C17H15ClF3NO4S, CAS 338424-60-5
3-[(4-Chlorophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS 338424-60-5C17H15ClF3NO4S
3-[(4-Chlorophenyl)sulfonyl]-N-(2,4-dichlorophenyl)-2-hydroxy-2-methylpropanamide chemical structure, C16H14Cl3NO4S, CAS 339275-80-8
3-[(4-Chlorophenyl)sulfonyl]-N-(2,4-dichlorophenyl)-2-hydroxy-2-methylpropanamide
CAS 339275-80-8C16H14Cl3NO4S
2-Hydroxy-3-[(4-methoxyphenyl)sulfonyl]-2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide chemical structure, C18H18F3NO5S, CAS 338956-20-0
2-Hydroxy-3-[(4-methoxyphenyl)sulfonyl]-2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide
CAS 338956-20-0C18H18F3NO5S
3-(4-Chlorophenyl)sulfonyl-N-(3-nitrophenyl)propanamide chemical structure, C15H13ClN2O5S, CAS 895464-51-4
3-(4-Chlorophenyl)sulfonyl-N-(3-nitrophenyl)propanamide
CAS 895464-51-4C15H13ClN2O5S
3-(4-Methylbenzenesulfonyl)-N-(3-nitrophenyl)propanamide chemical structure, C16H16N2O5S, CAS 697772-73-9
3-(4-Methylbenzenesulfonyl)-N-(3-nitrophenyl)propanamide
CAS 697772-73-9C16H16N2O5S
N-(2-Methylphenyl)-3-(4-methylphenyl)sulfonylpropanamide chemical structure, C17H19NO3S, CAS 697772-75-1
N-(2-Methylphenyl)-3-(4-methylphenyl)sulfonylpropanamide
CAS 697772-75-1C17H19NO3S
N-(4-Chlorophenyl)-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide chemical structure, C16H15ClFNO4S, CAS 338423-95-3
N-(4-Chlorophenyl)-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
CAS 338423-95-3C16H15ClFNO4S
3-[(4-Bromophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide chemical structure, C17H15BrF3NO4S, CAS 338424-45-6
3-[(4-Bromophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS 338424-45-6C17H15BrF3NO4S
3-[(3,4-Dichlorophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide chemical structure, C17H14Cl2F3NO4S, CAS 338424-41-2
3-[(3,4-Dichlorophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS 338424-41-2C17H14Cl2F3NO4S
2-Hydroxy-2-methyl-3-[(4-methylphenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]propanamide chemical structure, C18H18F3NO4S, CAS 338424-47-8
2-Hydroxy-2-methyl-3-[(4-methylphenyl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]propanamide
CAS 338424-47-8C18H18F3NO4S
2-Hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]-3-{[3-(trifluoromethyl)phenyl]sulfonyl}propanamide chemical structure, C18H15F6NO4S, CAS 339275-77-3
2-Hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]-3-{[3-(trifluoromethyl)phenyl]sulfonyl}propanamide
CAS 339275-77-3C18H15F6NO4S
2-Hydroxy-3-[(4-methoxyphenyl)sulfonyl]-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide chemical structure, C18H18F3NO5S, CAS 338424-48-9
2-Hydroxy-3-[(4-methoxyphenyl)sulfonyl]-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide
CAS 338424-48-9C18H18F3NO5S
3-[(4-Chlorophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide chemical structure, C17H15ClF3NO4S, CAS 338956-18-6
3-[(4-Chlorophenyl)sulfonyl]-2-hydroxy-2-methyl-N-[4-(trifluoromethyl)phenyl]propanamide
CAS 338956-18-6C17H15ClF3NO4S