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Murcko scaffold

3-Benzylpyrimidin-4-one scaffold

65 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
65
With full pages
4
Scaffold SMILES

O=c1ccncn1Cc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Benzylpyrimidin-4-one page
Murcko scaffold O=c1ccncn1Cc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

3-Benzylpyrimidin-4-one chemical structure, C11H10N2O, CAS 6146-23-2
3-Benzylpyrimidin-4-one
CAS 6146-23-2C11H10N2O
2-Amino-6-methyl-3-(4-nitrobenzyl)-4(3H)-pyrimidinone chemical structure, C12H12N4O3, CAS 339279-33-3
2-Amino-6-methyl-3-(4-nitrobenzyl)-4(3H)-pyrimidinone
CAS 339279-33-3C12H12N4O3
N,N-Dimethyl-N'-[4-methyl-1-(4-nitrobenzyl)-6-oxo-1,6-dihydro-2-pyrimidinyl]iminoformamide chemical structure, C15H17N5O3, CAS 339279-28-6
N,N-Dimethyl-N'-[4-methyl-1-(4-nitrobenzyl)-6-oxo-1,6-dihydro-2-pyrimidinyl]iminoformamide
CAS 339279-28-6C15H17N5O3
N'-[1-[(4-Fluorophenyl)methyl]-4-methyl-6-oxopyrimidin-2-yl]-N,N-dimethylmethanimidamide chemical structure, C15H17FN4O, CAS 338400-05-8
N'-[1-[(4-Fluorophenyl)methyl]-4-methyl-6-oxopyrimidin-2-yl]-N,N-dimethylmethanimidamide
CAS 338400-05-8C15H17FN4O
2-[(5-Bromo-2-chloro-4-methyl-6-oxo-1(6H)-pyrimidinyl)methyl]benzonitrile chemical structure, C13H9BrClN3O, CAS 844843-46-5
2-[(5-Bromo-2-chloro-4-methyl-6-oxo-1(6H)-pyrimidinyl)methyl]benzonitrile
CAS 844843-46-5C13H9BrClN3O
2-[(2-Chloro-5-ethyl-6-oxopyrimidin-1-yl)methyl]benzonitrile chemical structure, C14H12ClN3O, CAS 844843-53-4
2-[(2-Chloro-5-ethyl-6-oxopyrimidin-1-yl)methyl]benzonitrile
CAS 844843-53-4C14H12ClN3O
2-(2,5-Dichloro-6-oxo-6H-pyrimidin-1-ylmethyl)-benzonitrile chemical structure, C12H7Cl2N3O, CAS 844843-56-7
2-(2,5-Dichloro-6-oxo-6H-pyrimidin-1-ylmethyl)-benzonitrile
CAS 844843-56-7C12H7Cl2N3O
2-[(5-Bromo-2-chloro-6-oxo-1(6H)-pyrimidinyl)methyl]benzonitrile chemical structure, C12H7BrClN3O, CAS 844843-42-1
2-[(5-Bromo-2-chloro-6-oxo-1(6H)-pyrimidinyl)methyl]benzonitrile
CAS 844843-42-1C12H7BrClN3O
2-[(2-Chloro-4,5-dimethyl-6-oxopyrimidin-1-yl)methyl]benzonitrile chemical structure, C14H12ClN3O, CAS 844843-50-1
2-[(2-Chloro-4,5-dimethyl-6-oxopyrimidin-1-yl)methyl]benzonitrile
CAS 844843-50-1C14H12ClN3O
3-Benzyl-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C12H12N2OS, CAS 81560-08-9
3-Benzyl-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 81560-08-9C12H12N2OS
6-Amino-3-benzyl-2-(methylsulfanyl)pyrimidin-4(3H)-one chemical structure, C12H13N3OS, CAS 140396-41-4
6-Amino-3-benzyl-2-(methylsulfanyl)pyrimidin-4(3H)-one
CAS 140396-41-4C12H13N3OS
2-[(2-Chloro-5-methoxy-6-oxopyrimidin-1-yl)methyl]benzonitrile chemical structure, C13H10ClN3O2, CAS 844843-64-7
2-[(2-Chloro-5-methoxy-6-oxopyrimidin-1-yl)methyl]benzonitrile
CAS 844843-64-7C13H10ClN3O2
2-[(5-Bromo-4-tert-butyl-2-chloro-6-oxopyrimidin-1-yl)methyl]benzonitrile chemical structure, C16H15BrClN3O, CAS 1262205-85-5
2-[(5-Bromo-4-tert-butyl-2-chloro-6-oxopyrimidin-1-yl)methyl]benzonitrile
CAS 1262205-85-5C16H15BrClN3O
2-[(2-Chloro-5-iodo-6-oxopyrimidin-1-yl)methyl]benzonitrile chemical structure, C12H7ClIN3O, CAS 1262205-86-6
2-[(2-Chloro-5-iodo-6-oxopyrimidin-1-yl)methyl]benzonitrile
CAS 1262205-86-6C12H7ClIN3O
5-Bromo-3-(4-methoxybenzyl)pyrimidin-4(3H)-one chemical structure, C12H11BrN2O2, CAS 936635-88-0
5-Bromo-3-(4-methoxybenzyl)pyrimidin-4(3H)-one
CAS 936635-88-0C12H11BrN2O2
1-(3,4-Difluorobenzyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid chemical structure, C12H8F2N2O3, CAS 1204400-23-6
1-(3,4-Difluorobenzyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid
CAS 1204400-23-6C12H8F2N2O3
Methyl 1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylate chemical structure, C13H10F2N2O3, CAS 1204400-22-5
Methyl 1-(3,4-difluorobenzyl)-6-oxo-1,6-dihydropyrimidine-5-carboxylate
CAS 1204400-22-5C13H10F2N2O3
3-Benzyl-6-chloro-5-iodo-2-methylpyrimidin-4(3H)-one chemical structure, C12H10ClIN2O, CAS 917896-29-8
3-Benzyl-6-chloro-5-iodo-2-methylpyrimidin-4(3H)-one
CAS 917896-29-8C12H10ClIN2O
3-Benzyl-6-(methylamino)pyrimidin-4(3H)-one chemical structure, C12H13N3O, CAS 1035556-22-9
3-Benzyl-6-(methylamino)pyrimidin-4(3H)-one
CAS 1035556-22-9C12H13N3O
4-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-1-yl)methyl]benzonitrile chemical structure, C13H11N3O, CAS 1305014-00-9
4-[(4-Methyl-6-oxo-1,6-dihydropyrimidin-1-yl)methyl]benzonitrile
CAS 1305014-00-9C13H11N3O
3-[(4-Bromophenyl)methyl]-6-methyl-3,4-dihydropyrimidin-4-one chemical structure, C12H11BrN2O, CAS 1248095-13-7
3-[(4-Bromophenyl)methyl]-6-methyl-3,4-dihydropyrimidin-4-one
CAS 1248095-13-7C12H11BrN2O
4-((6-Oxopyrimidin-1-yl)methyl)benzoic acid chemical structure, C12H10N2O3, CAS 1479365-41-7
4-((6-Oxopyrimidin-1-yl)methyl)benzoic acid
CAS 1479365-41-7C12H10N2O3
5-Bromo-3-[(4-tert-butylphenyl)methyl]pyrimidin-4-one chemical structure, C15H17BrN2O, CAS 960298-82-2
5-Bromo-3-[(4-tert-butylphenyl)methyl]pyrimidin-4-one
CAS 960298-82-2C15H17BrN2O
5-Bromo-3-[(2-chlorophenyl)methyl]pyrimidin-4-one chemical structure, C11H8BrClN2O, CAS 960298-05-9
5-Bromo-3-[(2-chlorophenyl)methyl]pyrimidin-4-one
CAS 960298-05-9C11H8BrClN2O