Murcko scaffold
Methylenecyclobutane scaffold
331 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 5
- Chemicals
- 331
- With full pages
- 46
Scaffold SMILES
C=C1CCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 331 chemicals
Methylenecyclobutane
CAS 1120-56-5C5H8
3-Methylenecyclobutanecarbonitrile
CAS 15760-35-7C6H7N
3-Methylenecyclobutanecarboxylic acid
CAS 15760-36-8C6H8O2
Cyclobutanecarbonitrile, 2,2-dimethyl-3-methylene-
CAS 30758-34-0C8H11N
1-Amino-3-(phosphonomethylene)cyclobutane-1-carboxylic acid
CAS 140480-88-2C6H10NO5P
Ethylidenecyclobutane
CAS 1528-21-8C6H10
3-Methylenecyclobutylacetate
CAS 18218-27-4C7H10O2
(3-Methylidenecyclobutyl)methanol
CAS 10555-45-0C6H10O
Cyclobutane, (1-methylethylidene)-
CAS 1528-22-9C7H12
1-Ethyl-3-methylidenecyclobutane
CAS 56335-70-7C7H12
1,1-Dimethyl-3-methylenecyclobutane
CAS 19037-73-1C7H12
Cyclobutylidenemalononitrile
CAS 4415-81-0C7H6N2
Methanone, cyclobutylidene-
CAS 59078-45-4C5H6O
Cyclobutanecarboxylicacid, 1-amino-2-methylene-
CAS 259097-28-4C6H9NO2
Ethyl 1-((tert-butoxycarbonyl)amino)-3-methylenecyclobutane-1-carboxylate
CAS 281207-62-3C13H21NO4
Cyclobutane, 1-propenylidene-
CAS 61422-84-2C7H10
Methyl 3-methylenecyclobutanecarboxylate
CAS 15963-40-3C7H10O2
Cyclobutane, hexafluoro[2,2,2-trifluoro-1-(trifluoromethyl)ethylidene]-
CAS 74693-96-2C7F12
3-Methylenecyclobutanamine
CAS 100114-49-6C5H9N
(R)-(-)-2,2-Dimethyl-3-(1-methylethylidene)cyclobutanecarboxylic acid
CAS 827610-65-1C10H16O2
((1R)-2,2-Dimethyl-3-(propan-2-ylidene)cyclobutyl)methanol
CAS 754227-26-4C10H18O
1-Cyclobutylidenepropan-2-one
CAS 67223-98-7C7H10O
Methyl 2-methylidenecyclobutane-1-carboxylate
CAS 71092-56-3C7H10O2
(1E)-1-(2-Fluorocyclobutylidene)propan-2-one
C7H9FO
- (Bromomethylidene)cyclobutane1905-06-2C5H7Br
- (Dibromomethylidene)cyclobutane82833-95-2C5H6Br2
- 2-(Dimethylamino)-3-methylidenecyclobutane-1-carbonitrile344353-68-0C8H12N2
- Methyl cyanocyclobutylideneacetate98714-66-0C8H9NO2
- 1 suppliers2-Cyclobutylideneacetonitrile27784-69-6C6H7N
- 2-Cyclobutylideneacetaldehyde97592-29-5C6H8O
- 1,1-Difluoro-3-methylene-cyclobutane110654-33-6C5H6F2
- 3-Methylenecyclobutanecarbonyl chloride98198-78-8C6H7ClO
- 1-(Bromomethyl)-3-methylenecyclobutane10555-46-1C6H9Br
- 1-Methyl-3-methylidenecyclobutane15189-18-1C6H10
- 2-Cyano-2-cyclobutylideneacetamide113555-36-5C7H8N2O
- 1-Chloro-3-methylidenecyclobutane-1-carbonitrile71802-58-9C6H6ClN
- 1-(tert-Butylsulfanyl)-3-(cyanomethylidene)cyclobutane-1-carbonitrile110812-12-9C11H14N2S
- Ethyl 2-cyclobutylidene-2-fluoroacetate119059-92-6C8H11FO2
- 2-Cyclobutylidene-2-fluoroethan-1-ol119059-93-7C6H9FO
- tert-Butyl 3-methylidenecyclobutane-1-carboxylate122699-51-8C10H16O2
- 3-Methylenecyclobutanol68423-20-1C5H8O
- 3-(Methoxymethylidene)-1-methylcyclobutane-1-carbaldehyde132803-27-1C8H12O2
- Methyl (1S,2R,3Z)-3-ethylidene-2-methylcyclobutane-1-carboxylate134111-63-0C9H14O2
- Cyclobutanecarboxylic acid, 3-ethylidene-2-methyl-, methyl ester, [1R-134175-97-6C9H14O2
- 1,1-Dimethylethyl 2-cyclobutylideneacetate27784-70-9C10H16O2
- 3-Cyclobutylidene-1,1,1-trifluoropropan-2-one146801-52-7C7H7F3O
- 3-Propylidenecyclobutan-1-ol159419-77-9C7H12O
- 2-Cyclobutylideneethan-1-ol4415-76-3C6H10O