Murcko scaffold
Azetidin-3-one scaffold
72 chemicals on CompoundList share this ring system.
- Rings
- 1
- Scaffold atoms
- 5
- Chemicals
- 72
- With full pages
- 19
Scaffold SMILES
O=C1CNC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 72 chemicals
Azetidin-3-one
CAS 54044-11-0C3H5NO
3-Oxo-azetidine-1-carboxylic acid tert-butyl ester
CAS 398489-26-4C8H13NO3
Ethyl 3-oxoazetidine-1-carboxylate
CAS 105258-88-6C6H9NO3
Azetidin-3-one Hydrochloride
CAS 17557-84-5C3H6ClNO
1-Acetylazetidin-3-one
CAS 179894-05-4C5H7NO2
Methyl 3-oxoazetidine-1-carboxylate
CAS 118972-98-8C5H7NO3
tert-Butyl (2S)-2-methyl-3-oxoazetidine-1-carboxylate
CAS 171919-76-9C9H15NO3
1-Isobutylazetidin-3-one
CAS 341978-87-8C7H13NO
1-(Methylsulfonyl)azetidin-3-one
CAS 1144032-02-9C4H7NO3S
Methyl 3-oxoazetidine-2-carboxylate
CAS 1822544-78-4C5H7NO3
1-Methylazetidin-3-one
CAS 1144032-03-0C4H7NO
1-Isopropyl-2-methylazetidin-3-one
CAS 547753-49-1C7H13NO
3-Azetidinone, 2-methyl-1-(2-methylpropyl)-
CAS 547753-62-8C8H15NO
2-Ethyl-2-methyl-1-propan-2-ylazetidin-3-one
CAS 547753-54-8C9H17NO
2-Methyl-1-propan-2-yl-2-prop-2-enylazetidin-3-one
CAS 547753-73-1C10H17NO
1-Isopropyl-2-methyl-2-propylazetidin-3-one
CAS 547753-71-9C10H19NO
1-tert-Butylazetidin-3-one
CAS 1159170-38-3C7H13NO
Allyl 3-oxoazetidine-1-carboxylate
CAS 1198283-54-3C7H9NO3
1-Azetidinecarboxylic acid, 2-methyl-3-oxo-, 1,1-dimethylethyl ester
CAS 1408076-36-7C9H15NO3
1-Propionylazetidin-3-one
CAS 1401222-95-4C6H9NO2
1-(Trifluoroacetyl)azetidin-3-one
CAS 1803610-57-2C5H4F3NO2
1-Azetidinecarboxylic acid, 2-methyl-3-oxo-, 1,1-dimethylethyl ester, (2R)-
CAS 1638744-93-0C9H15NO3
1-Azetidinecarboxylic acid, 2-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]-3-oxo-, 1,1-dimethylethyl ester, (2S)-
CAS 1390637-89-4C17H30N2O5
tert-Butyl 2,2-dimethyl-3-oxoazetidine-1-carboxylate
CAS 1628748-83-3C10H17NO3
- 1-(Ethanesulfonyl)azetidin-3-one1401222-91-0C5H9NO3S
- 1-(Isopropylsulfonyl)azetidin-3-one1401222-93-2C6H11NO3S
- N-Ethyl-3-oxoazetidine-1-carboxamide1401222-87-4C6H10N2O2
- tert-Butyl 2-(2-methoxyethyl)-3-oxoazetidine-1-carboxylate1909312-42-0C11H19NO4
- tert-Butyl 2-(methoxymethyl)-3-oxoazetidine-1-carboxylate1909314-38-0C10H17NO4
- 1-Methylazetidin-3-one hydrochloride1818847-43-6C4H8ClNO
- 2,2-Dimethylazetidin-3-one2387001-44-5C5H9NO
- 2-(Hydroxymethyl)azetidin-3-one1824219-28-4C4H7NO2
- 1-Acryloylazetidin-3-one1445851-47-7C6H7NO2
- N-tert-Butyl-3-oxoazetidine-1-carboxamide1401222-86-3C8H14N2O2
- Propan-2-yl 3-oxoazetidine-1-carboxylate1401222-88-5C7H11NO3
- 3-Oxo-N-(propan-2-yl)azetidine-1-carboxamide1401222-85-2C7H12N2O2
- 2-(2-Methoxyethyl)azetidin-3-one1934983-21-7C6H11NO2
- 2-(Methoxymethyl)azetidin-3-one1934547-44-0C5H9NO2
- 2-(Trifluoromethyl)azetidin-3-one1935906-08-3C4H4F3NO
- 2-Methoxyethyl 3-oxoazetidine-1-carboxylate1401222-90-9C7H11NO4
- tert-Butyl (2S)-2-allyl-3-oxo-azetidine-1-carboxylate1983184-73-1C11H17NO3
- tert-Butyl (2R)-2-allyl-3-oxo-aZetidine-1-carboxylate1983184-76-4C11H17NO3
- tert-Butyl (2S)-3-oxo-2-(propan-2-yl)azetidine-1-carboxylate1983184-80-0C11H19NO3
- tert-Butyl 2,4-dimethyl-3-oxoazetidine-1-carboxylate1975120-98-9C10H17NO3
- tert-Butyl cis-2,4-dimethyl-3-oxoazetidine-1-carboxylate2165562-21-8C10H17NO3
- tert-Butyl trans-2,4-dimethyl-3-oxoazetidine-1-carboxylate2165821-25-8C10H17NO3
- 2,2,2-Trifluoroethyl 3-oxoazetidine-1-carboxylate2287287-77-6C6H6F3NO3
- 1-tert-Butyl 2-ethyl 3-oxoazetidine-1,2-dicarboxylate2168125-49-1C11H17NO5