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Murcko scaffold

1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-phenyl- scaffold

109 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
109
With full pages
23
Scaffold SMILES

O=C1C2CC=CCC2C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-phenyl- page
Murcko scaffold O=C1C2CC=CCC2C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 109 chemicals

1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-((2-oxopropoxy)phenyl)- chemical structure, C17H17NO4, CAS 54393-00-9
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-((2-oxopropoxy)phenyl)-
CAS 54393-00-9C17H17NO4
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-(4-(2-propynyloxy)phenyl)- chemical structure, C17H15NO3, CAS 55680-89-2
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-(4-(2-propynyloxy)phenyl)-
CAS 55680-89-2C17H15NO3
2-(4-Chlorophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C14H12ClNO2, CAS 43069-64-3
2-(4-Chlorophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 43069-64-3C14H12ClNO2
2-(3-Chlorophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C14H12ClNO2, CAS 19849-16-2
2-(3-Chlorophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 19849-16-2C14H12ClNO2
RefChem:313935 chemical structure, C14H13NO2, CAS 20141-47-3
RefChem:313935
CAS 20141-47-3C14H13NO2
(3aR,7aR)-2-Phenyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione chemical structure, C14H13NO2, CAS 63975-86-0
(3aR,7aR)-2-Phenyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione
CAS 63975-86-0C14H13NO2
RefChem:345372 chemical structure, C18H19NO4, CAS 5628-31-9
RefChem:345372
CAS 5628-31-9C18H19NO4
RefChem:382075 chemical structure, C15H15NO2, CAS 96599-47-2
RefChem:382075
CAS 96599-47-2C15H15NO2
4-(4-Methyl-1,3-dioxo-3a,4,7,7a-tetrahydro-1H-isoindol-2(3H)-yl)benzoic acid chemical structure, C16H15NO4, CAS 324001-29-8
4-(4-Methyl-1,3-dioxo-3a,4,7,7a-tetrahydro-1H-isoindol-2(3H)-yl)benzoic acid
CAS 324001-29-8C16H15NO4
2-(4-Iodophenyl)-5,6-dimethyl-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C16H16INO2, CAS 295361-51-2
2-(4-Iodophenyl)-5,6-dimethyl-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 295361-51-2C16H16INO2
5,6-Dimethyl-2-phenyl-3a,4,7,7a-tetrahydro-isoindole-1,3-dione chemical structure, C16H17NO2, CAS 96599-48-3
5,6-Dimethyl-2-phenyl-3a,4,7,7a-tetrahydro-isoindole-1,3-dione
CAS 96599-48-3C16H17NO2
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-phenyl- chemical structure, C14H13NO2, CAS 2015-58-9
1H-Isoindole-1,3(2H)-dione, 3a,4,7,7a-tetrahydro-2-phenyl-
CAS 2015-58-9C14H13NO2
5,6-Dimethyl-2-(2-propoxyphenyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione chemical structure, C19H23NO3, CAS 300818-83-1
5,6-Dimethyl-2-(2-propoxyphenyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione
CAS 300818-83-1C19H23NO3
2-(4-Nitrophenyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione chemical structure, C14H12N2O4, CAS 43069-65-4
2-(4-Nitrophenyl)-3a,4,7,7a-tetrahydroisoindole-1,3-dione
CAS 43069-65-4C14H12N2O4
2-(4-Methoxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C15H15NO3, CAS 43069-60-9
2-(4-Methoxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 43069-60-9C15H15NO3
4,6-Dimethyl-2-phenyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione chemical structure, C16H17NO2, CAS 467447-10-5
4,6-Dimethyl-2-phenyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione
CAS 467447-10-5C16H17NO2
2-(3-Hydroxyphenyl)-5-methyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione chemical structure, C15H15NO3, CAS 201989-55-1
2-(3-Hydroxyphenyl)-5-methyl-3a,4,7,7a-tetrahydroisoindole-1,3-dione
CAS 201989-55-1C15H15NO3
2-(4-Ethoxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C16H17NO3, CAS 55680-87-0
2-(4-Ethoxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 55680-87-0C16H17NO3
5-Methyl-2-(3-nitrophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C15H14N2O4, CAS 418804-45-2
5-Methyl-2-(3-nitrophenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 418804-45-2C15H14N2O4
4-(4,6-Dimethyl-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)benzoic acid chemical structure, C17H17NO4, CAS 380443-04-9
4-(4,6-Dimethyl-1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)benzoic acid
CAS 380443-04-9C17H17NO4
Ethyl 4-(1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)benzoate chemical structure, C17H17NO4, CAS 352644-28-1
Ethyl 4-(1,3-dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)benzoate
CAS 352644-28-1C17H17NO4
2-(5-Chloro-2-hydroxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C14H12ClNO3, CAS 312920-63-1
2-(5-Chloro-2-hydroxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 312920-63-1C14H12ClNO3
3-(1,3-Dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)benzoic acid chemical structure, C15H13NO4, CAS 89446-98-0
3-(1,3-Dioxo-1,3,3a,4,7,7a-hexahydro-2H-isoindol-2-yl)benzoic acid
CAS 89446-98-0C15H13NO4
2-(3-Hydroxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione chemical structure, C14H13NO3, CAS 54398-99-1
2-(3-Hydroxyphenyl)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione
CAS 54398-99-1C14H13NO3