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Murcko scaffold

Ring system with 3 rings and 23 atoms

53 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
53
With full pages
6
Scaffold SMILES

O=C(COc1ccccc1)Nc1ccccc1N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(COc1ccccc1)Nc1ccccc1N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

2-(3,5-Dimethylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C20H24N2O3, CAS 528863-29-8
2-(3,5-Dimethylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 528863-29-8C20H24N2O3
2-(2-Methylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C19H22N2O3, CAS 526205-28-7
2-(2-Methylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 526205-28-7C19H22N2O3
2-(4-Methylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C19H22N2O3, CAS 528841-52-3
2-(4-Methylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 528841-52-3C19H22N2O3
N-[3-Chloro-2-(morpholin-4-yl)phenyl]-2-phenoxyacetamide chemical structure, C18H19ClN2O3, CAS 1000940-31-7
N-[3-Chloro-2-(morpholin-4-yl)phenyl]-2-phenoxyacetamide
CAS 1000940-31-7C18H19ClN2O3
2-(4-Chloro-2-methylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C19H21ClN2O3, CAS 529501-79-9
2-(4-Chloro-2-methylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 529501-79-9C19H21ClN2O3
2-(2,4-Dichlorophenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C18H18Cl2N2O3, CAS 528875-34-5
2-(2,4-Dichlorophenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 528875-34-5C18H18Cl2N2O3
2-(3,4-Dimethylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C20H24N2O3, CAS 529491-02-9
2-(3,4-Dimethylphenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 529491-02-9C20H24N2O3
2-(4-Chlorophenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C18H19ClN2O3, CAS 528844-58-8
2-(4-Chlorophenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 528844-58-8C18H19ClN2O3
N-(2-Morpholin-4-yl-phenyl)-2-m-tolyloxy-acetamide chemical structure, C19H22N2O3, CAS 529498-96-2
N-(2-Morpholin-4-yl-phenyl)-2-m-tolyloxy-acetamide
CAS 529498-96-2C19H22N2O3
2-(2-Chlorophenoxy)-N-(2-morpholin-4-ylphenyl)acetamide chemical structure, C18H19ClN2O3, CAS 528576-08-1
2-(2-Chlorophenoxy)-N-(2-morpholin-4-ylphenyl)acetamide
CAS 528576-08-1C18H19ClN2O3
N-(5-Chloro-2-morpholin-4-ylphenyl)-2-(4-methoxyphenoxy)acetamide chemical structure, C19H21ClN2O4, CAS 714206-93-6
N-(5-Chloro-2-morpholin-4-ylphenyl)-2-(4-methoxyphenoxy)acetamide
CAS 714206-93-6C19H21ClN2O4
2-(4-Chlorophenoxy)-2-methyl-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]propanamide chemical structure, C21H22ClF3N2O3, CAS 380331-18-0
2-(4-Chlorophenoxy)-2-methyl-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]propanamide
CAS 380331-18-0C21H22ClF3N2O3
N-(3-Chloro-2-morpholin-4-ylphenyl)-2-(2-nitrophenoxy)acetamide chemical structure, C18H18ClN3O5, CAS 712290-70-5
N-(3-Chloro-2-morpholin-4-ylphenyl)-2-(2-nitrophenoxy)acetamide
CAS 712290-70-5C18H18ClN3O5
N-(5-Chloro-2-morpholin-4-ylphenyl)-2-(2,4-dimethylphenoxy)acetamide chemical structure, C20H23ClN2O3, CAS 712291-44-6
N-(5-Chloro-2-morpholin-4-ylphenyl)-2-(2,4-dimethylphenoxy)acetamide
CAS 712291-44-6C20H23ClN2O3
2-[5-Methyl-2-(propan-2-yl)phenoxy]-N-[2-(morpholin-4-yl)phenyl]acetamide chemical structure, C22H28N2O3, CAS 527716-57-0
2-[5-Methyl-2-(propan-2-yl)phenoxy]-N-[2-(morpholin-4-yl)phenyl]acetamide
CAS 527716-57-0C22H28N2O3
2-(4-Chlorophenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide chemical structure, C19H18ClF3N2O3, CAS 638158-65-3
2-(4-Chlorophenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide
CAS 638158-65-3C19H18ClF3N2O3
2-(4-Bromophenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide chemical structure, C19H18BrF3N2O3, CAS 638158-69-7
2-(4-Bromophenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide
CAS 638158-69-7C19H18BrF3N2O3
2-(5-Methyl-2-propan-2-ylphenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide chemical structure, C23H27F3N2O3, CAS 640252-06-8
2-(5-Methyl-2-propan-2-ylphenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide
CAS 640252-06-8C23H27F3N2O3
2-(2,4-Dichlorophenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide chemical structure, C19H17Cl2F3N2O3, CAS 327976-45-4
2-(2,4-Dichlorophenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide
CAS 327976-45-4C19H17Cl2F3N2O3
2-(3-Methylphenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide chemical structure, C20H21F3N2O3, CAS 638158-73-3
2-(3-Methylphenoxy)-N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide
CAS 638158-73-3C20H21F3N2O3
2-(4-Chlorophenoxy)-2-methyl-N-(2-morpholin-4-ylphenyl)propanamide chemical structure, C20H23ClN2O3, CAS 847785-70-0
2-(4-Chlorophenoxy)-2-methyl-N-(2-morpholin-4-ylphenyl)propanamide
CAS 847785-70-0C20H23ClN2O3
N-[2-Morpholin-4-yl-5-(trifluoromethyl)phenyl]-2-(4-propan-2-ylphenoxy)acetamide chemical structure, C22H25F3N2O3, CAS 640252-02-4
N-[2-Morpholin-4-yl-5-(trifluoromethyl)phenyl]-2-(4-propan-2-ylphenoxy)acetamide
CAS 640252-02-4C22H25F3N2O3
2-(2,4-Dichlorophenoxy)-N-(2-morpholin-4-ylphenyl)propanamide chemical structure, C19H20Cl2N2O3, CAS 701257-38-7
2-(2,4-Dichlorophenoxy)-N-(2-morpholin-4-ylphenyl)propanamide
CAS 701257-38-7C19H20Cl2N2O3
N-(4-Chloro-2-morpholin-4-ylphenyl)-2-(4-chlorophenoxy)acetamide chemical structure, C18H18Cl2N2O3, CAS 881593-10-8
N-(4-Chloro-2-morpholin-4-ylphenyl)-2-(4-chlorophenoxy)acetamide
CAS 881593-10-8C18H18Cl2N2O3