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Murcko scaffold

Ring system with 3 rings and 24 atoms

33 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
24
Chemicals
33
With full pages
10
Scaffold SMILES

O=C(NC(=S)Nc1ccccc1N1CCOCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC(=S)Nc1ccccc1N1CCOCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 33 of 33 chemicals

4-tert-Butyl-N-{[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}benzamide chemical structure, C23H26F3N3O2S, CAS 640252-98-8
4-tert-Butyl-N-{[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}benzamide
CAS 640252-98-8C23H26F3N3O2S
3-Ethoxy-N-{[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}benzamide chemical structure, C21H22F3N3O3S, CAS 640253-06-1
3-Ethoxy-N-{[2-(morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}benzamide
CAS 640253-06-1C21H22F3N3O3S
N-{[2-(Morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}-3-(propan-2-yloxy)benzamide chemical structure, C22H24F3N3O3S, CAS 640253-14-1
N-{[2-(Morpholin-4-yl)-5-(trifluoromethyl)phenyl]carbamothioyl}-3-(propan-2-yloxy)benzamide
CAS 640253-14-1C22H24F3N3O3S
3,4-Dimethyl-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C20H23N3O2S, CAS 528534-11-4
3,4-Dimethyl-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 528534-11-4C20H23N3O2S
5-Chloro-2-methoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C19H20ClN3O3S, CAS 527737-67-3
5-Chloro-2-methoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 527737-67-3C19H20ClN3O3S
4-Iodo-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C18H18IN3O2S, CAS 530109-07-0
4-Iodo-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 530109-07-0C18H18IN3O2S
2,3-Dichloro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C18H17Cl2N3O2S, CAS 530107-39-2
2,3-Dichloro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 530107-39-2C18H17Cl2N3O2S
N-[(5-Chloro-2-morpholin-4-ylphenyl)carbamothioyl]-3,4-dimethoxybenzamide chemical structure, C20H22ClN3O4S, CAS 823824-11-9
N-[(5-Chloro-2-morpholin-4-ylphenyl)carbamothioyl]-3,4-dimethoxybenzamide
CAS 823824-11-9C20H22ClN3O4S
N-[(5-Chloro-2-morpholin-4-ylphenyl)carbamothioyl]-2-methoxy-3-methylbenzamide chemical structure, C20H22ClN3O3S, CAS 835896-42-9
N-[(5-Chloro-2-morpholin-4-ylphenyl)carbamothioyl]-2-methoxy-3-methylbenzamide
CAS 835896-42-9C20H22ClN3O3S
3,4-Dichloro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C18H17Cl2N3O2S, CAS 530122-38-4
3,4-Dichloro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 530122-38-4C18H17Cl2N3O2S
N-[(2-Morpholin-4-ylphenyl)carbamothioyl]-4-propan-2-yloxybenzamide chemical structure, C21H25N3O3S, CAS 529492-22-6
N-[(2-Morpholin-4-ylphenyl)carbamothioyl]-4-propan-2-yloxybenzamide
CAS 529492-22-6C21H25N3O3S
3-Ethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C20H23N3O3S, CAS 527756-23-6
3-Ethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 527756-23-6C20H23N3O3S
N-[(2-Morpholin-4-ylphenyl)carbamothioyl]-3-nitrobenzamide chemical structure, C18H18N4O4S, CAS 527711-65-5
N-[(2-Morpholin-4-ylphenyl)carbamothioyl]-3-nitrobenzamide
CAS 527711-65-5C18H18N4O4S
3-Chloro-4-ethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C20H22ClN3O3S, CAS 530097-45-1
3-Chloro-4-ethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 530097-45-1C20H22ClN3O3S
4-Bromo-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C18H18BrN3O2S, CAS 528833-05-8
4-Bromo-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 528833-05-8C18H18BrN3O2S
4-Methoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]-3-nitrobenzamide chemical structure, C19H20N4O5S, CAS 530094-11-2
4-Methoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]-3-nitrobenzamide
CAS 530094-11-2C19H20N4O5S
4-tert-Butyl-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C22H27N3O2S, CAS 528582-72-1
4-tert-Butyl-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 528582-72-1C22H27N3O2S
2-Chloro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]-4-nitrobenzamide chemical structure, C18H17ClN4O4S, CAS 527711-62-2
2-Chloro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]-4-nitrobenzamide
CAS 527711-62-2C18H17ClN4O4S
3-Bromo-4-ethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C20H22BrN3O3S, CAS 528874-03-5
3-Bromo-4-ethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 528874-03-5C20H22BrN3O3S
N-[[2-(4-Morpholinyl)anilino]-sulfanylidenemethyl]-4-nitrobenzamide chemical structure, C18H18N4O4S, CAS 528889-11-4
N-[[2-(4-Morpholinyl)anilino]-sulfanylidenemethyl]-4-nitrobenzamide
CAS 528889-11-4C18H18N4O4S
3-Methoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C19H21N3O3S, CAS 528862-16-0
3-Methoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 528862-16-0C19H21N3O3S
2,6-Dimethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C20H23N3O4S, CAS 689759-58-8
2,6-Dimethoxy-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 689759-58-8C20H23N3O4S
2-Chloro-4-fluoro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide chemical structure, C18H17ClFN3O2S, CAS 640757-77-3
2-Chloro-4-fluoro-N-[(2-morpholin-4-ylphenyl)carbamothioyl]benzamide
CAS 640757-77-3C18H17ClFN3O2S
4-Bromo-N-[[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]carbamothioyl]benzamide chemical structure, C19H17BrF3N3O2S, CAS 638150-65-9
4-Bromo-N-[[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]carbamothioyl]benzamide
CAS 638150-65-9C19H17BrF3N3O2S