CompoundList
Sign in
Murcko scaffold

3-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione scaffold

75 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
75
With full pages
3
Scaffold SMILES

O=C1CCC(n2c(=O)[nH]c3ccccc32)C(=O)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione page
Murcko scaffold O=C1CCC(n2c(=O)[nH]c3ccccc32)C(=O)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 75 chemicals

E3 ligase Ligand 29 chemical structure, C13H13N3O3, CAS 2154341-52-1
E3 ligase Ligand 29
CAS 2154341-52-1C13H13N3O3
3-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione chemical structure, C12H11N3O3, CAS 2412439-24-6
3-(2-Oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione
CAS 2412439-24-6C12H11N3O3
3-(5-Bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione chemical structure, C13H12BrN3O3, CAS 2300099-98-1
3-(5-Bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione
CAS 2300099-98-1C13H12BrN3O3
3-(2,3-Dihydro-3-methyl-4-nitro-2-oxo-1H-benzimidazol-1-yl)-2,6-piperidinedione chemical structure, C13H12N4O5, CAS 2304754-08-1
3-(2,3-Dihydro-3-methyl-4-nitro-2-oxo-1H-benzimidazol-1-yl)-2,6-piperidinedione
CAS 2304754-08-1C13H12N4O5
3-(5-Amino-3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidine-2,6-dione chemical structure, C13H14N4O3, CAS 2304753-45-3
3-(5-Amino-3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidine-2,6-dione
CAS 2304753-45-3C13H14N4O3
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile chemical structure, C14H12N4O3, CAS 2304754-42-3
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile
CAS 2304754-42-3C14H12N4O3
3-(5-Ethynyl-3-methyl-2-oxo-benzimidazol-1-yl)piperidine-2,6-dione chemical structure, C15H13N3O3, CAS 2304754-82-1
3-(5-Ethynyl-3-methyl-2-oxo-benzimidazol-1-yl)piperidine-2,6-dione
CAS 2304754-82-1C15H13N3O3
3-(5-Amino-3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidine-2,6-dione hydrochloride chemical structure, C13H15ClN4O3, CAS 2304753-79-3
3-(5-Amino-3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)piperidine-2,6-dione hydrochloride
CAS 2304753-79-3C13H15ClN4O3
3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione chemical structure, C13H12BrN3O3, CAS 2304754-51-4
3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione
CAS 2304754-51-4C13H12BrN3O3
3-(5-(Aminomethyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-1-yl)piperidine-2,6-dione chemical structure, C14H16N4O3, CAS 2304753-87-3
3-(5-(Aminomethyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[D]imidazol-1-yl)piperidine-2,6-dione
CAS 2304753-87-3C14H16N4O3
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carbonitrile chemical structure, C14H12N4O3, CAS 2304754-14-9
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carbonitrile
CAS 2304754-14-9C14H12N4O3
3-(4-Amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione chemical structure, C13H14N4O3, CAS 2304753-42-0
3-(4-Amino-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione
CAS 2304753-42-0C13H14N4O3
3-(4-Hydroxy-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione chemical structure, C13H13N3O4, CAS 2304753-47-5
3-(4-Hydroxy-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione
CAS 2304753-47-5C13H13N3O4
3-[4-(Aminomethyl)-3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]piperidine-2,6-dione chemical structure, C14H16N4O3, CAS 2360521-20-4
3-[4-(Aminomethyl)-3-methyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]piperidine-2,6-dione
CAS 2360521-20-4C14H16N4O3
3-[1-(2,6-Dioxo-3-piperidyl)-3-methyl-2-oxo-benzimidazol-4-yl]propanal chemical structure, C16H17N3O4, CAS 2357114-08-8
3-[1-(2,6-Dioxo-3-piperidyl)-3-methyl-2-oxo-benzimidazol-4-yl]propanal
CAS 2357114-08-8C16H17N3O4
E3 ligase Ligand 31 chemical structure, C16H17N3O4, CAS 2357114-13-5
E3 ligase Ligand 31
CAS 2357114-13-5C16H17N3O4
3-[4-(4-Hydroxybut-1-ynyl)-3-methyl-2-oxobenzo[D]imidazol-1-yl]hexahydropyridine-2,6-dione chemical structure, C17H17N3O4, CAS 2360518-94-9
3-[4-(4-Hydroxybut-1-ynyl)-3-methyl-2-oxobenzo[D]imidazol-1-yl]hexahydropyridine-2,6-dione
CAS 2360518-94-9C17H17N3O4
3-[4-(3-Hydroxypropyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl]piperidine-2,6-dione chemical structure, C16H19N3O4, CAS 2357114-07-7
3-[4-(3-Hydroxypropyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl]piperidine-2,6-dione
CAS 2357114-07-7C16H19N3O4
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbaldehyde chemical structure, C14H13N3O4, CAS 2357116-00-6
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbaldehyde
CAS 2357116-00-6C14H13N3O4
3-(5-(3-(2-(2-Hydroxyethoxy)ethoxy)prop-1-yn-1-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione chemical structure, C20H23N3O6, CAS 2357117-17-8
3-(5-(3-(2-(2-Hydroxyethoxy)ethoxy)prop-1-yn-1-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-2,6-dione
CAS 2357117-17-8C20H23N3O6
3-[5-(3-Hydroxypropyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl]piperidine-2,6-dione chemical structure, C16H19N3O4, CAS 2357114-12-4
3-[5-(3-Hydroxypropyl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl]piperidine-2,6-dione
CAS 2357114-12-4C16H19N3O4
3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-1-methylpiperidine-2,6-dione chemical structure, C14H14BrN3O3, CAS 2357116-36-8
3-(4-Bromo-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-1-methylpiperidine-2,6-dione
CAS 2357116-36-8C14H14BrN3O3
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carbaldehyde chemical structure, C14H13N3O4, CAS 2360518-87-0
1-(2,6-Dioxopiperidin-3-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-4-carbaldehyde
CAS 2360518-87-0C14H13N3O4
3-[4-(3-Hydroxyprop-1-yn-1-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl]piperidine-2,6-dione chemical structure, C16H15N3O4, CAS 2412058-85-4
3-[4-(3-Hydroxyprop-1-yn-1-yl)-3-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl]piperidine-2,6-dione
CAS 2412058-85-4C16H15N3O4