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Murcko scaffold

2-Phenylisoindoline scaffold

54 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
54
With full pages
18
Scaffold SMILES

c1ccc(N2Cc3ccccc3C2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenylisoindoline page
Murcko scaffold c1ccc(N2Cc3ccccc3C2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 54 chemicals

2-Methyl-2-phenylisoindolinium iodide chemical structure, C15H16IN, CAS 16840-49-6
2-Methyl-2-phenylisoindolinium iodide
CAS 16840-49-6C15H16IN
2-Phenylisoindoline chemical structure, C14H13N, CAS 19375-67-8
2-Phenylisoindoline
CAS 19375-67-8C14H13N
2-(3,5-Dimethylphenyl)isoindoline chemical structure, C16H17N, CAS 113439-98-8
2-(3,5-Dimethylphenyl)isoindoline
CAS 113439-98-8C16H17N
2-(3-Chlorophenyl)isoindoline chemical structure, C14H12ClN, CAS 109949-63-5
2-(3-Chlorophenyl)isoindoline
CAS 109949-63-5C14H12ClN
4-(1,3-Dihydro-2H-isoindol-2-yl)benzoic acid chemical structure, C15H13NO2, CAS 329715-35-7
4-(1,3-Dihydro-2H-isoindol-2-yl)benzoic acid
CAS 329715-35-7C15H13NO2
2-(3-Nitrophenyl)isoindoline chemical structure, C14H12N2O2, CAS 359811-06-6
2-(3-Nitrophenyl)isoindoline
CAS 359811-06-6C14H12N2O2
Ethyl 4-(1,3-dihydro-2H-isoindol-2-yl)benzoate chemical structure, C17H17NO2, CAS 654635-00-4
Ethyl 4-(1,3-dihydro-2H-isoindol-2-yl)benzoate
CAS 654635-00-4C17H17NO2
1-[3-(1,3-Dihydro-2H-isoindol-2-yl)phenyl]-1-ethanone chemical structure, C16H15NO, CAS 357302-54-6
1-[3-(1,3-Dihydro-2H-isoindol-2-yl)phenyl]-1-ethanone
CAS 357302-54-6C16H15NO
2-(3-Bromophenyl)-2,3-dihydro-1H-isoindole chemical structure, C14H12BrN, CAS 273217-84-8
2-(3-Bromophenyl)-2,3-dihydro-1H-isoindole
CAS 273217-84-8C14H12BrN
4-(1,3-Dihydro-2H-isoindol-2-yl)phenol chemical structure, C14H13NO, CAS 41790-54-9
4-(1,3-Dihydro-2H-isoindol-2-yl)phenol
CAS 41790-54-9C14H13NO
4-(1,3-Dihydro-isoindol-2-yl)-2-hydroxy-benzoic acid chemical structure, C15H13NO3, CAS 296770-21-3
4-(1,3-Dihydro-isoindol-2-yl)-2-hydroxy-benzoic acid
CAS 296770-21-3C15H13NO3
4-(1,3-Dihydro-isoindol-2-yl)-phenylamine chemical structure, C14H14N2, CAS 359897-36-2
4-(1,3-Dihydro-isoindol-2-yl)-phenylamine
CAS 359897-36-2C14H14N2
4-(Isoindolin-2-yl)-2-methoxybenzaldehyde chemical structure, C16H15NO2, CAS 347325-46-6
4-(Isoindolin-2-yl)-2-methoxybenzaldehyde
CAS 347325-46-6C16H15NO2
4-(1,3-Dihydro-2H-isoindol-2-yl)-2-methylbenzaldehyde chemical structure, C16H15NO, CAS 347325-40-0
4-(1,3-Dihydro-2H-isoindol-2-yl)-2-methylbenzaldehyde
CAS 347325-40-0C16H15NO
1-(4-(Isoindolin-2-yl)phenyl)ethanone chemical structure, C16H15NO, CAS 77820-60-1
1-(4-(Isoindolin-2-yl)phenyl)ethanone
CAS 77820-60-1C16H15NO
1H-Isoindole, 2,3-dihydro-2-(4-methoxyphenyl)- chemical structure, C15H15NO, CAS 73357-44-5
1H-Isoindole, 2,3-dihydro-2-(4-methoxyphenyl)-
CAS 73357-44-5C15H15NO
2-(3-Chloro-4-methoxyphenyl)-5,6-dimethyl-1,3-dihydroisoindole chemical structure, C17H18ClNO, CAS 693805-57-1
2-(3-Chloro-4-methoxyphenyl)-5,6-dimethyl-1,3-dihydroisoindole
CAS 693805-57-1C17H18ClNO
2-(3-Chloro-4-methoxyphenyl)-1,3-dihydroisoindole chemical structure, C15H14ClNO, CAS 693819-94-2
2-(3-Chloro-4-methoxyphenyl)-1,3-dihydroisoindole
CAS 693819-94-2C15H14ClNO
2-(2,5-Dimethoxyphenyl)-5,6-dimethylisoindoline chemical structure, C18H21NO2, CAS 693822-65-0
2-(2,5-Dimethoxyphenyl)-5,6-dimethylisoindoline
CAS 693822-65-0C18H21NO2
3-(1,3-Dihydro-isoindol-2-yl)-benzoic acid chemical structure, C15H13NO2, CAS 5604-83-1
3-(1,3-Dihydro-isoindol-2-yl)-benzoic acid
CAS 5604-83-1C15H13NO2
1H-Isoindole, 2,3-dihydro-2-(2-methoxyphenyl)- chemical structure, C15H15NO, CAS 109514-64-9
1H-Isoindole, 2,3-dihydro-2-(2-methoxyphenyl)-
CAS 109514-64-9C15H15NO
1H-Isoindole, 2,3-dihydro-2-(3-methoxyphenyl)- chemical structure, C15H15NO, CAS 73357-40-1
1H-Isoindole, 2,3-dihydro-2-(3-methoxyphenyl)-
CAS 73357-40-1C15H15NO
1H-Isoindole, 2-(2-chlorophenyl)-2,3-dihydro- chemical structure, C14H12ClN, CAS 73357-41-2
1H-Isoindole, 2-(2-chlorophenyl)-2,3-dihydro-
CAS 73357-41-2C14H12ClN
3-(5,6-Dimethyl-1,3-dihydro-2H-isoindol-2-yl)benzoic acid chemical structure, C17H17NO2, CAS 884497-56-7
3-(5,6-Dimethyl-1,3-dihydro-2H-isoindol-2-yl)benzoic acid
CAS 884497-56-7C17H17NO2