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Murcko scaffold

3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-phenylpyrrolidine-2,5-dione scaffold

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
12
With full pages
8
Scaffold SMILES

O=C1CC(NNc2nc3ccccc3s2)C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-phenylpyrrolidine-2,5-dione page
Murcko scaffold O=C1CC(NNc2nc3ccccc3s2)C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-phenylpyrrolidine-2,5-dione chemical structure, C17H14N4O2S, CAS 956790-36-6
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-phenylpyrrolidine-2,5-dione
CAS 956790-36-6C17H14N4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione chemical structure, C18H13F3N4O2S, CAS 956763-47-6
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-[3-(trifluoromethyl)phenyl]pyrrolidine-2,5-dione
CAS 956763-47-6C18H13F3N4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-ethylphenyl)pyrrolidine-2,5-dione chemical structure, C19H18N4O2S, CAS 956356-67-5
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-ethylphenyl)pyrrolidine-2,5-dione
CAS 956356-67-5C19H18N4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazino]-1-(4-methoxyphenyl)-2,5-pyrrolidinedione chemical structure, C18H16N4O3S, CAS 956262-70-7
3-[2-(1,3-Benzothiazol-2-yl)hydrazino]-1-(4-methoxyphenyl)-2,5-pyrrolidinedione
CAS 956262-70-7C18H16N4O3S
Ethyl 4-{3-[2-(1,3-benzothiazol-2-yl)hydrazinyl]-2,5-dioxopyrrolidin-1-yl}benzoate chemical structure, C20H18N4O4S, CAS 956263-20-0
Ethyl 4-{3-[2-(1,3-benzothiazol-2-yl)hydrazinyl]-2,5-dioxopyrrolidin-1-yl}benzoate
CAS 956263-20-0C20H18N4O4S
3-[2-(1,3-Benzothiazol-2-yl)hydrazino]-1-(2,4-dichlorophenyl)-2,5-pyrrolidinedione chemical structure, C17H12Cl2N4O2S, CAS 956183-38-3
3-[2-(1,3-Benzothiazol-2-yl)hydrazino]-1-(2,4-dichlorophenyl)-2,5-pyrrolidinedione
CAS 956183-38-3C17H12Cl2N4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(3-methoxyphenyl)pyrrolidine-2,5-dione chemical structure, C18H16N4O3S, CAS 956370-64-2
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(3-methoxyphenyl)pyrrolidine-2,5-dione
CAS 956370-64-2C18H16N4O3S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione chemical structure, C17H13FN4O2S, CAS 956795-84-9
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-fluorophenyl)pyrrolidine-2,5-dione
CAS 956795-84-9C17H13FN4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione chemical structure, C19H18N4O3S, CAS 956373-20-9
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-ethoxyphenyl)pyrrolidine-2,5-dione
CAS 956373-20-9C19H18N4O3S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-methylphenyl)pyrrolidine-2,5-dione chemical structure, C18H16N4O2S, CAS 956781-61-6
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-methylphenyl)pyrrolidine-2,5-dione
CAS 956781-61-6C18H16N4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(3,4-dimethylphenyl)pyrrolidine-2,5-dione chemical structure, C19H18N4O2S, CAS 956183-64-5
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(3,4-dimethylphenyl)pyrrolidine-2,5-dione
CAS 956183-64-5C19H18N4O2S
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-chloro-2-methylphenyl)pyrrolidine-2,5-dione chemical structure, C18H15ClN4O2S, CAS 957490-82-3
3-[2-(1,3-Benzothiazol-2-yl)hydrazinyl]-1-(4-chloro-2-methylphenyl)pyrrolidine-2,5-dione
CAS 957490-82-3C18H15ClN4O2S