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Murcko scaffold

Ring system with 3 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
16
With full pages
1
Scaffold SMILES

O=c1c(-c2ccccc2)c[nH]cc1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c(-c2ccccc2)c[nH]cc1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

Fluridone chemical structure, C19H14F3NO, CAS 59756-60-4
Fluridone
CAS 59756-60-4C19H14F3NO
4(1H)-Pyridinone, 3-(4-hydroxyphenyl)-1-methyl-5-(3-(trifluoromethyl)phenyl)- chemical structure, C19H14F3NO2, CAS 71792-19-3
4(1H)-Pyridinone, 3-(4-hydroxyphenyl)-1-methyl-5-(3-(trifluoromethyl)phenyl)-
CAS 71792-19-3C19H14F3NO2
4(1H)-Pyridinone, 3-(4-fluorophenyl)-1-methyl-5-(3-trifluoromethyl)phenyl)- chemical structure, C19H13F4NO, CAS 59756-73-9
4(1H)-Pyridinone, 3-(4-fluorophenyl)-1-methyl-5-(3-trifluoromethyl)phenyl)-
CAS 59756-73-9C19H13F4NO
Pyridin-4-one, 3-(3-chlorophenyl)-1-methyl-5-phenyl- chemical structure, C18H14ClNO, CAS 59757-01-6
Pyridin-4-one, 3-(3-chlorophenyl)-1-methyl-5-phenyl-
CAS 59757-01-6C18H14ClNO
4(1H)-Pyridinone, 3-(3-methoxyphenyl)-1-methyl-5-phenyl- chemical structure, C19H17NO2, CAS 59757-08-3
4(1H)-Pyridinone, 3-(3-methoxyphenyl)-1-methyl-5-phenyl-
CAS 59757-08-3C19H17NO2
4(1H)-Pyridinone, 1-methyl-3-phenyl-5-(3-propoxyphenyl)- chemical structure, C21H21NO2, CAS 59757-83-4
4(1H)-Pyridinone, 1-methyl-3-phenyl-5-(3-propoxyphenyl)-
CAS 59757-83-4C21H21NO2
1,2,6-Trimethyl-3,5-diphenylpyridin-4-one chemical structure, C20H19NO, CAS 42215-29-2
1,2,6-Trimethyl-3,5-diphenylpyridin-4-one
CAS 42215-29-2C20H19NO
1-Methyl-3,5-bis(3-trifluoromethylphenyl)-4(1H)-pyridone chemical structure, C20H13F6NO, CAS 59756-61-5
1-Methyl-3,5-bis(3-trifluoromethylphenyl)-4(1H)-pyridone
CAS 59756-61-5C20H13F6NO
3-(3-Chlorophenyl)-5-(4-chlorophenyl)-1-methylpyridin-4(1H)-one chemical structure, C18H13Cl2NO, CAS 59756-64-8
3-(3-Chlorophenyl)-5-(4-chlorophenyl)-1-methylpyridin-4(1H)-one
CAS 59756-64-8C18H13Cl2NO
3-Phenyl-1-(prop-2-en-1-yl)-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one chemical structure, C21H16F3NO, CAS 59756-69-3
3-Phenyl-1-(prop-2-en-1-yl)-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one
CAS 59756-69-3C21H16F3NO
3,5-Bis(3-chlorophenyl)-1-methylpyridin-4(1H)-one chemical structure, C18H13Cl2NO, CAS 59757-03-8
3,5-Bis(3-chlorophenyl)-1-methylpyridin-4(1H)-one
CAS 59757-03-8C18H13Cl2NO
1-Methyl-3-(3-methylphenyl)-5-phenylpyridin-4(1H)-one chemical structure, C19H17NO, CAS 59757-04-9
1-Methyl-3-(3-methylphenyl)-5-phenylpyridin-4(1H)-one
CAS 59757-04-9C19H17NO
3-(3-Bromophenyl)-1-methyl-5-phenylpyridin-4(1H)-one chemical structure, C18H14BrNO, CAS 59757-16-3
3-(3-Bromophenyl)-1-methyl-5-phenylpyridin-4(1H)-one
CAS 59757-16-3C18H14BrNO
1-Methyl-3,5-diphenylpyridin-4(1H)-one chemical structure, C18H15NO, CAS 43121-60-4
1-Methyl-3,5-diphenylpyridin-4(1H)-one
CAS 43121-60-4C18H15NO
1-Ethyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one chemical structure, C20H16F3NO, CAS 59757-22-1
1-Ethyl-3-phenyl-5-[3-(trifluoromethyl)phenyl]pyridin-4(1H)-one
CAS 59757-22-1C20H16F3NO
2-Bromo-1-methyl-3,5-diphenylpyridin-4(1H)-one chemical structure, C18H14BrNO, CAS 87443-31-0
2-Bromo-1-methyl-3,5-diphenylpyridin-4(1H)-one
CAS 87443-31-0C18H14BrNO