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Murcko scaffold

Ring system with 3 rings and 20 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
14
With full pages
4
Scaffold SMILES

O=C(CCc1ccccc1)Nc1cc2c(s1)CCCC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCc1ccccc1)Nc1cc2c(s1)CCCC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

2-(3-Phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C18H20N2O2S, CAS 307545-52-4
2-(3-Phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 307545-52-4C18H20N2O2S
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-phenylpropanamide chemical structure, C18H18N2OS, CAS 321945-24-8
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-phenylpropanamide
CAS 321945-24-8C18H18N2OS
Ethyl 2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate chemical structure, C20H23NO3S, CAS 329226-56-4
Ethyl 2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS 329226-56-4C20H23NO3S
Methyl 2-(3-phenylpropanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate chemical structure, C19H21NO3S, CAS 329221-93-4
Methyl 2-(3-phenylpropanoylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
CAS 329221-93-4C19H21NO3S
6-Methyl-2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C19H22N2O2S, CAS 329221-97-8
6-Methyl-2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 329221-97-8C19H22N2O2S
2-{[3-(4-Methoxyphenyl)propanoyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C20H24N2O3S, CAS 352676-87-0
2-{[3-(4-Methoxyphenyl)propanoyl]amino}-6-methyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 352676-87-0C20H24N2O3S
6-Ethyl-2-[(3-phenylpropanoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide chemical structure, C20H24N2O2S, CAS 352705-08-9
6-Ethyl-2-[(3-phenylpropanoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS 352705-08-9C20H24N2O2S
2-[(3-Phenylpropanoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid chemical structure, C18H19NO3S, CAS 342595-08-8
2-[(3-Phenylpropanoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid
CAS 342595-08-8C18H19NO3S
2-(3-(4-Methoxyphenyl)propanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C19H22N2O3S, CAS 545364-07-6
2-(3-(4-Methoxyphenyl)propanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 545364-07-6C19H22N2O3S
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(4-methoxyphenyl)propanamide chemical structure, C19H20N2O2S, CAS 438473-43-9
N-(3-Cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-3-(4-methoxyphenyl)propanamide
CAS 438473-43-9C19H20N2O2S
N-Methyl-2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C19H22N2O2S, CAS 892982-35-3
N-Methyl-2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 892982-35-3C19H22N2O2S
N-(3-Cyano(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl))-3-(4-methylphenyl)propana mide chemical structure, C19H20N2OS, CAS 905767-42-2
N-(3-Cyano(4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl))-3-(4-methylphenyl)propana mide
CAS 905767-42-2C19H20N2OS
Methyl 2-[[3-(2-chlorophenyl)-1-oxopropyl]amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate chemical structure, C19H20ClNO3S, CAS 925180-11-6
Methyl 2-[[3-(2-chlorophenyl)-1-oxopropyl]amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS 925180-11-6C19H20ClNO3S
N,6-dimethyl-2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide chemical structure, C20H24N2O2S, CAS 892981-89-4
N,6-dimethyl-2-(3-phenylpropanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide
CAS 892981-89-4C20H24N2O2S