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Murcko scaffold

Ring system with 2 rings and 12 atoms

59 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
59
With full pages
6
Scaffold SMILES

c1ccc(Sc2ncn[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2ncn[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 59 chemicals

1H-1,2,4-Triazole, 3-((2,4-dinitrophenyl)thio)- chemical structure, C8H5N5O4S, CAS 73768-82-8
1H-1,2,4-Triazole, 3-((2,4-dinitrophenyl)thio)-
CAS 73768-82-8C8H5N5O4S
3-(5-Chloro-2-nitrophenyl)sulfanyl-4-methyl-1,2,4-triazole chemical structure, C9H7ClN4O2S, CAS 327050-69-1
3-(5-Chloro-2-nitrophenyl)sulfanyl-4-methyl-1,2,4-triazole
CAS 327050-69-1C9H7ClN4O2S
5-(4-Chlorophenyl)sulfanyl-1-methyl-3-nitro-1,2,4-triazole chemical structure, C9H7ClN4O2S, CAS 667901-20-4
5-(4-Chlorophenyl)sulfanyl-1-methyl-3-nitro-1,2,4-triazole
CAS 667901-20-4C9H7ClN4O2S
1-Methyl-5-(4-methylphenyl)sulfanyl-3-nitro-1,2,4-triazole chemical structure, C10H10N4O2S, CAS 692275-86-8
1-Methyl-5-(4-methylphenyl)sulfanyl-3-nitro-1,2,4-triazole
CAS 692275-86-8C10H10N4O2S
1-[5-(4-Methylphenyl)sulfanyl-3-nitro-1,2,4-triazol-1-yl]propan-2-one chemical structure, C12H12N4O3S, CAS 692281-07-5
1-[5-(4-Methylphenyl)sulfanyl-3-nitro-1,2,4-triazol-1-yl]propan-2-one
CAS 692281-07-5C12H12N4O3S
1-{5-[(4-Chlorophenyl)sulfanyl]-3-nitro-1H-1,2,4-triazol-1-yl}acetone chemical structure, C11H9ClN4O3S, CAS 727386-85-8
1-{5-[(4-Chlorophenyl)sulfanyl]-3-nitro-1H-1,2,4-triazol-1-yl}acetone
CAS 727386-85-8C11H9ClN4O3S
4-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-3-nitrobenzoic acid chemical structure, C10H8N4O4S, CAS 380431-58-3
4-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-3-nitrobenzoic acid
CAS 380431-58-3C10H8N4O4S
5-Nitro-2-(1H-1,2,4-triazol-5-ylsulfanyl)benzoic acid chemical structure, C9H6N4O4S, CAS 554405-04-8
5-Nitro-2-(1H-1,2,4-triazol-5-ylsulfanyl)benzoic acid
CAS 554405-04-8C9H6N4O4S
4-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-3-nitrobenzaldehyde chemical structure, C10H8N4O3S, CAS 721417-20-5
4-[(4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl]-3-nitrobenzaldehyde
CAS 721417-20-5C10H8N4O3S
5-Chloro-2-((4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl)aniline chemical structure, C9H9ClN4S, CAS 733030-65-4
5-Chloro-2-((4-methyl-4H-1,2,4-triazol-3-yl)sulfanyl)aniline
CAS 733030-65-4C9H9ClN4S
3-Methyl-5-{[2-nitro-4-(trifluoromethyl)phenyl]sulphanyl}-4H-1,2,4-triazol-4-amine chemical structure, C10H8F3N5O2S, CAS 300664-71-5
3-Methyl-5-{[2-nitro-4-(trifluoromethyl)phenyl]sulphanyl}-4H-1,2,4-triazol-4-amine
CAS 300664-71-5C10H8F3N5O2S
5-{[2-Nitro-4-(trifluoromethyl)phenyl]sulfanyl}-1H-1,2,4-triazol-3-amine chemical structure, C9H6F3N5O2S, CAS 261929-10-6
5-{[2-Nitro-4-(trifluoromethyl)phenyl]sulfanyl}-1H-1,2,4-triazol-3-amine
CAS 261929-10-6C9H6F3N5O2S
N1-(5-{[2-nitro-4-(trifluoromethyl)phenyl]thio}-1H-1,2,4-triazol-3-yl)-2,3,3-trichloroacrylamide chemical structure, C12H5Cl3F3N5O3S, CAS 4728-29-4
N1-(5-{[2-nitro-4-(trifluoromethyl)phenyl]thio}-1H-1,2,4-triazol-3-yl)-2,3,3-trichloroacrylamide
CAS 4728-29-4C12H5Cl3F3N5O3S
{5-Chloro-2-[(4,5-dimethyl-4H-1,2,4-triazol-3-yl)thio]phenyl}amine chemical structure, C10H11ClN4S, CAS 893778-98-8
{5-Chloro-2-[(4,5-dimethyl-4H-1,2,4-triazol-3-yl)thio]phenyl}amine
CAS 893778-98-8C10H11ClN4S
3-(2,4,6-Trimethylphenyl)thio-1H-1,2,4-triazole chemical structure, C11H13N3S, CAS 158091-64-6
3-(2,4,6-Trimethylphenyl)thio-1H-1,2,4-triazole
CAS 158091-64-6C11H13N3S
1-{5-[(2-Aminophenyl)sulfanyl]-3-chloro-1H-1,2,4-triazol-1-yl}acetone chemical structure, C11H11ClN4OS, CAS 914357-51-0
1-{5-[(2-Aminophenyl)sulfanyl]-3-chloro-1H-1,2,4-triazol-1-yl}acetone
CAS 914357-51-0C11H11ClN4OS
1-Ethyl-5-(phenylthio)-1H-1,2,4-triazole chemical structure, C10H11N3S, CAS 535961-28-5
1-Ethyl-5-(phenylthio)-1H-1,2,4-triazole
CAS 535961-28-5C10H11N3S
1-{5-[(2-Aminophenyl)sulfanyl]-3-bromo-1H-1,2,4-triazol-1-yl}acetone chemical structure, C11H11BrN4OS, CAS 914357-54-3
1-{5-[(2-Aminophenyl)sulfanyl]-3-bromo-1H-1,2,4-triazol-1-yl}acetone
CAS 914357-54-3C11H11BrN4OS
4-((4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl)aniline chemical structure, C9H10N4S, CAS 497851-88-4
4-((4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl)aniline
CAS 497851-88-4C9H10N4S
2-((4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl)aniline chemical structure, C9H10N4S, CAS 923230-55-1
2-((4-Methyl-4H-1,2,4-triazol-3-yl)sulfanyl)aniline
CAS 923230-55-1C9H10N4S
2-[(1-Methyl-3-nitro-1H-1,2,4-triazol-5-yl)sulfanyl]aniline chemical structure, C9H9N5O2S, CAS 919970-51-7
2-[(1-Methyl-3-nitro-1H-1,2,4-triazol-5-yl)sulfanyl]aniline
CAS 919970-51-7C9H9N5O2S
2-[(3-Bromo-1-methyl-1H-1,2,4-triazol-5-yl)sulfanyl]aniline chemical structure, C9H9BrN4S, CAS 919970-80-2
2-[(3-Bromo-1-methyl-1H-1,2,4-triazol-5-yl)sulfanyl]aniline
CAS 919970-80-2C9H9BrN4S
2-Nitro-5-[(1H-1,2,4-triazol-5-yl)sulfanyl]aniline chemical structure, C8H7N5O2S, CAS 55564-45-9
2-Nitro-5-[(1H-1,2,4-triazol-5-yl)sulfanyl]aniline
CAS 55564-45-9C8H7N5O2S
4-[(1H-1,2,4-Triazol-5-yl)sulfanyl]benzene-1,2-diamine chemical structure, C8H9N5S, CAS 55564-46-0
4-[(1H-1,2,4-Triazol-5-yl)sulfanyl]benzene-1,2-diamine
CAS 55564-46-0C8H9N5S