CompoundList
Sign in
Murcko scaffold

Pyrido(4,3-d)pyrimidin-4(3H)-one scaffold

49 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
49
With full pages
5
Scaffold SMILES

O=c1[nH]cnc2ccncc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyrido(4,3-d)pyrimidin-4(3H)-one page
Murcko scaffold O=c1[nH]cnc2ccncc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

5,7-Dichloro-3-methylpyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H5Cl2N3O, CAS 1263077-21-9
5,7-Dichloro-3-methylpyrido[4,3-d]pyrimidin-4(3H)-one
CAS 1263077-21-9C8H5Cl2N3O
2-(Chloromethyl)-3-methylpyrido[4,3-d]pyrimidin-4-one chemical structure, C9H8ClN3O, CAS 1263413-72-4
2-(Chloromethyl)-3-methylpyrido[4,3-d]pyrimidin-4-one
CAS 1263413-72-4C9H8ClN3O
7-Fluoropyrido[4,3-d]pyrimidin-4(1H)-one chemical structure, C7H4FN3O, CAS 171178-37-3
7-Fluoropyrido[4,3-d]pyrimidin-4(1H)-one
CAS 171178-37-3C7H4FN3O
Pyrido(4,3-d)pyrimidin-4(3H)-one chemical structure, C7H5N3O, CAS 16952-64-0
Pyrido(4,3-d)pyrimidin-4(3H)-one
CAS 16952-64-0C7H5N3O
7-Aminopyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C7H6N4O, CAS 171178-36-2
7-Aminopyrido[4,3-d]pyrimidin-4(3H)-one
CAS 171178-36-2C7H6N4O
7-Amino-5-bromo-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H7BrN4O, CAS 915190-04-4
7-Amino-5-bromo-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one
CAS 915190-04-4C8H7BrN4O
7-Amino-5-bromopyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C7H5BrN4O, CAS 915190-03-3
7-Amino-5-bromopyrido[4,3-d]pyrimidin-4(3H)-one
CAS 915190-03-3C7H5BrN4O
2-tert-Butyl-pyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C11H13N3O, CAS 705291-54-9
2-tert-Butyl-pyrido[4,3-d]pyrimidin-4(3H)-one
CAS 705291-54-9C11H13N3O
5,7-Dichloropyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C7H3Cl2N3O, CAS 918898-11-0
5,7-Dichloropyrido[4,3-d]pyrimidin-4(3H)-one
CAS 918898-11-0C7H3Cl2N3O
2-Methylpyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H7N3O, CAS 16952-45-7
2-Methylpyrido[4,3-d]pyrimidin-4(3H)-one
CAS 16952-45-7C8H7N3O
2-(tert-Butyl)-8-iodopyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C11H12IN3O, CAS 705292-04-2
2-(tert-Butyl)-8-iodopyrido[4,3-d]pyrimidin-4(3H)-one
CAS 705292-04-2C11H12IN3O
8-Bromopyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C7H4BrN3O, CAS 1256353-15-7
8-Bromopyrido[4,3-d]pyrimidin-4(3H)-one
CAS 1256353-15-7C7H4BrN3O
8-Bromo-2-(methylsulfanyl)-3H,4H-pyrido(4,3-d)pyrimidin-4-one chemical structure, C8H6BrN3OS, CAS 1709905-39-4
8-Bromo-2-(methylsulfanyl)-3H,4H-pyrido(4,3-d)pyrimidin-4-one
CAS 1709905-39-4C8H6BrN3OS
5-Methyl-7-(methylthio)-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidine-8-carbonitrile chemical structure, C10H8N4OS, CAS 1604041-58-8
5-Methyl-7-(methylthio)-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidine-8-carbonitrile
CAS 1604041-58-8C10H8N4OS
5-Methyl-7-(methylsulfonyl)-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidine-8-carbonitrile chemical structure, C10H8N4O3S, CAS 1604041-59-9
5-Methyl-7-(methylsulfonyl)-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidine-8-carbonitrile
CAS 1604041-59-9C10H8N4O3S
5-Chloropyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C7H4ClN3O, CAS 711027-55-3
5-Chloropyrido[4,3-d]pyrimidin-4(3H)-one
CAS 711027-55-3C7H4ClN3O
7-Chloro-3H,4H-pyrido(4,3-d)pyrimidin-4-one chemical structure, C7H4ClN3O, CAS 1650574-62-1
7-Chloro-3H,4H-pyrido(4,3-d)pyrimidin-4-one
CAS 1650574-62-1C7H4ClN3O
5-Methylpyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H7N3O, CAS 1266149-53-4
5-Methylpyrido[4,3-d]pyrimidin-4(3H)-one
CAS 1266149-53-4C8H7N3O
2-(Chloromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H6ClN3O, CAS 1379226-36-4
2-(Chloromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one
CAS 1379226-36-4C8H6ClN3O
7-Chloro-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H6ClN3O, CAS 2383628-69-9
7-Chloro-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one
CAS 2383628-69-9C8H6ClN3O
7-Chloro-2-(dimethylamino)pyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C9H9ClN4O, CAS 1800540-20-8
7-Chloro-2-(dimethylamino)pyrido[4,3-d]pyrimidin-4(3H)-one
CAS 1800540-20-8C9H9ClN4O
7-Chloro-8-fluoropyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C7H3ClFN3O, CAS 2454396-93-9
7-Chloro-8-fluoropyrido[4,3-d]pyrimidin-4(3H)-one
CAS 2454396-93-9C7H3ClFN3O
7-Chloro-8-fluoro-2-(methylthio)pyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H5ClFN3OS, CAS 2454491-18-8
7-Chloro-8-fluoro-2-(methylthio)pyrido[4,3-d]pyrimidin-4(3H)-one
CAS 2454491-18-8C8H5ClFN3OS
7-Chloro-8-fluoro-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one chemical structure, C8H5ClFN3O, CAS 2454491-20-2
7-Chloro-8-fluoro-2-methylpyrido[4,3-d]pyrimidin-4(3H)-one
CAS 2454491-20-2C8H5ClFN3O