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Murcko scaffold

Ring system with 2 rings and 17 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
17
Chemicals
11
With full pages
10
Scaffold SMILES

O=C(Cc1ccccc1)NN=Cc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)NN=Cc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2-(4-Nitrophenyl)-N-(1-thiophen-2-ylethylideneamino)acetamide chemical structure, C14H13N3O3S, CAS 6399-26-4
2-(4-Nitrophenyl)-N-(1-thiophen-2-ylethylideneamino)acetamide
CAS 6399-26-4C14H13N3O3S
2-(4-Chlorophenyl)-N-[(E)-thiophen-2-ylmethylideneamino]acetamide chemical structure, C13H11ClN2OS, CAS 328902-12-1
2-(4-Chlorophenyl)-N-[(E)-thiophen-2-ylmethylideneamino]acetamide
CAS 328902-12-1C13H11ClN2OS
2-(4-Chlorophenyl)-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]acetamide chemical structure, C14H13ClN2OS, CAS 1351580-78-3
2-(4-Chlorophenyl)-N-[(E)-(3-methylthiophen-2-yl)methylideneamino]acetamide
CAS 1351580-78-3C14H13ClN2OS
2-Hydroxy-2-phenyl-N-[(E)-thiophen-2-ylmethylideneamino]acetamide chemical structure, C13H12N2O2S, CAS 351997-77-8
2-Hydroxy-2-phenyl-N-[(E)-thiophen-2-ylmethylideneamino]acetamide
CAS 351997-77-8C13H12N2O2S
2-Phenyl-N-[(E)-1-thiophen-2-ylethylideneamino]acetamide chemical structure, C14H14N2OS, CAS 113874-48-9
2-Phenyl-N-[(E)-1-thiophen-2-ylethylideneamino]acetamide
CAS 113874-48-9C14H14N2OS
(E)-2-(4-Nitrophenyl)-N'-(thiophen-2-ylmethylene)acetohydrazide chemical structure, C13H11N3O3S, CAS 405152-85-4
(E)-2-(4-Nitrophenyl)-N'-(thiophen-2-ylmethylene)acetohydrazide
CAS 405152-85-4C13H11N3O3S
2-Phenyl-N'-(2-thienylmethylene)acetohydrazide chemical structure, C13H12N2OS, CAS 113875-04-0
2-Phenyl-N'-(2-thienylmethylene)acetohydrazide
CAS 113875-04-0C13H12N2OS
N'-[(E)-(5-Chlorothiophen-2-yl)methylidene]-2-hydroxy-2-phenylacetohydrazide chemical structure, C13H11ClN2O2S, CAS 419553-36-9
N'-[(E)-(5-Chlorothiophen-2-yl)methylidene]-2-hydroxy-2-phenylacetohydrazide
CAS 419553-36-9C13H11ClN2O2S
N'-[(E)-(4-Bromothiophen-2-yl)methylidene]-2-hydroxy-2-phenylacetohydrazide chemical structure, C13H11BrN2O2S, CAS 496797-52-5
N'-[(E)-(4-Bromothiophen-2-yl)methylidene]-2-hydroxy-2-phenylacetohydrazide
CAS 496797-52-5C13H11BrN2O2S
2-Hydroxy-N'-[(E)-(3-methylthiophen-2-yl)methylidene]-2-phenylacetohydrazide chemical structure, C14H14N2O2S, CAS 328910-25-4
2-Hydroxy-N'-[(E)-(3-methylthiophen-2-yl)methylidene]-2-phenylacetohydrazide
CAS 328910-25-4C14H14N2O2S
N'-[(1E)-1-(5-Bromothiophen-2-yl)ethylidene]-2-hydroxy-2-phenylacetohydrazide chemical structure, C14H13BrN2O2S, CAS 352663-65-1
N'-[(1E)-1-(5-Bromothiophen-2-yl)ethylidene]-2-hydroxy-2-phenylacetohydrazide
CAS 352663-65-1C14H13BrN2O2S