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Murcko scaffold

Ring system with 3 rings and 22 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
12
With full pages
4
Scaffold SMILES

c1ccc(OCCNc2cccc(N3CCNCC3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCCNc2cccc(N3CCNCC3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

N-[2-(4-Chlorophenoxy)ethyl]-5-(3,5-dimethylpiperazin-1-yl)-2-nitroaniline chemical structure, C20H25ClN4O3, CAS 296770-18-8
N-[2-(4-Chlorophenoxy)ethyl]-5-(3,5-dimethylpiperazin-1-yl)-2-nitroaniline
CAS 296770-18-8C20H25ClN4O3
N-[2-(3-Methoxyphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C20H26N4O4, CAS 327050-40-8
N-[2-(3-Methoxyphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 327050-40-8C20H26N4O4
2-[4-[3-[2-(4-Ethylphenoxy)ethylamino]-4-nitrophenyl]piperazin-1-yl]ethanol chemical structure, C22H30N4O4, CAS 296771-64-7
2-[4-[3-[2-(4-Ethylphenoxy)ethylamino]-4-nitrophenyl]piperazin-1-yl]ethanol
CAS 296771-64-7C22H30N4O4
N-[2-(4-Methoxyphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C20H26N4O4, CAS 327050-47-5
N-[2-(4-Methoxyphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 327050-47-5C20H26N4O4
N-[2-(3-Methylphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C20H26N4O3, CAS 327050-49-7
N-[2-(3-Methylphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 327050-49-7C20H26N4O3
N-[2-(4-Chlorophenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C19H23ClN4O3, CAS 327050-51-1
N-[2-(4-Chlorophenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 327050-51-1C19H23ClN4O3
N-[2-(4-Chlorophenoxy)ethyl]-2-nitro-5-piperazin-1-ylaniline chemical structure, C18H21ClN4O3, CAS 330829-97-5
N-[2-(4-Chlorophenoxy)ethyl]-2-nitro-5-piperazin-1-ylaniline
CAS 330829-97-5C18H21ClN4O3
N-[2-(4-Chlorophenoxy)ethyl]-5-(4-methylsulfonylpiperazin-1-yl)-2-nitroaniline chemical structure, C19H23ClN4O5S, CAS 347356-08-5
N-[2-(4-Chlorophenoxy)ethyl]-5-(4-methylsulfonylpiperazin-1-yl)-2-nitroaniline
CAS 347356-08-5C19H23ClN4O5S
5-(4-Methylpiperazin-1-yl)-2-nitro-N-(2-phenoxyethyl)aniline chemical structure, C19H24N4O3, CAS 354988-74-2
5-(4-Methylpiperazin-1-yl)-2-nitro-N-(2-phenoxyethyl)aniline
CAS 354988-74-2C19H24N4O3
N-[2-(2-Methylphenoxy)ethyl]-2-nitro-5-piperazin-1-ylaniline chemical structure, C19H24N4O3, CAS 347355-55-9
N-[2-(2-Methylphenoxy)ethyl]-2-nitro-5-piperazin-1-ylaniline
CAS 347355-55-9C19H24N4O3
N-[2-(3,4-Dimethylphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline chemical structure, C21H28N4O3, CAS 327050-45-3
N-[2-(3,4-Dimethylphenoxy)ethyl]-5-(4-methylpiperazin-1-yl)-2-nitroaniline
CAS 327050-45-3C21H28N4O3
4-(4-Methyl-1-piperazinyl)-2-[(2-phenoxyethyl)amino]benzonitrile chemical structure, C20H24N4O, CAS 897027-32-6
4-(4-Methyl-1-piperazinyl)-2-[(2-phenoxyethyl)amino]benzonitrile
CAS 897027-32-6C20H24N4O